Background Antineoplastic drug exposure is a major problem in regard to caregivers’ health. The aim of the present study was assess perception, knowledge, and handling practices all occupation level categories two oncology day hospitalization units compounding regarding risk antineoplastic drugs. Methods This descriptive study, performed through face-to-face interviews, concurrently assessed drugs five different job four settings. work part larger comprehensive project examining surface...

Introduction: Health care workers handling antineoplastic drugs (ADs) are at risk of carcinogenic, mutagenic and reproductive toxic risks (CMR). The aim this study was to assess the impact lack knowledge (K) on perception (P) protective practices (PP) related home-based chemotherapy (HC) by home nurses. Methods: This conducted in Normandy among A questionnaire developed explore K, P PP ADs nurses working with four different providers from two hospitals. Results: Among 28 included, 25.93% had...

Background Antineoplastic drugs exposure is a major problem for caregivers’ health. The aim of this study to assess blood contamination with irinotecan and its two metabolites in centralized pharmacy unit cytotoxic drug preparations workers before after protective equipment changes. Methods took place university hospital was performed parts, (Round 1: R1) changes 2: R2). Collection staff samples UHPLC-MS/MS. Plasma red cell (SN38; APC) were determined validated analytical method detection...

Caregivers in healthcare settings are exposed to a risk of antineoplastic drug contamination which can lead adverse health effects. Biological monitoring is necessary estimate the actual level exposure these workers. This study was conducted with aim assessing blood levels by irinotecan and its metabolites pharmaceutical staff operating inside outside compounding unit.The took place within unit French comprehensive cancer centre. Blood samples were collected from pharmacy workers unit,...

Two surgical techniques used for peritoneal metastasis involve a risk of exposure to antineoplastic drugs (ADs): hyperthermic intraperitoneal chemotherapy (HIPEC) and pressurized aerosol (PIPAC). The objective this study was assess the differences in perception, training, knowledge risks as well protection practices occupational exposures all worker categories.This descriptive study, led two hospitals from distant French regions, performed through face-to-face interview assessed handling ADs...

Introduction Health care workers handling antineoplastic drugs (ADs) are at risk of mutagenicity and adverse reproductive effects. Despite protective equipment AD guidelines, levels still detected in caregivers oncology units. This study attempted to assess blood contamination by irinotecan its metabolites all health day hospital units according activities specific each employment category. Methods The was performed two different hospitals: a university comprehensive cancer centre....

Healthcare workers are exposed to hazardous drugs such as antineoplastic drugs, which have potential carcinogenic, mutagenic and teratogenic effects. Protective measures must be taken after appropriate staff training handle in a safe way. The objective was assess perception, knowledge, practices regarding the risk of exposure healthcare three French compounding units.This descriptive study based on questionnaire made 33 questions divided into five sections related handling drugs: perception...

<h3>Background</h3> Candidaemia/invasive candidiasis are becoming emerging problems in hospital practice due to an increased prevalence of susceptible hosts, i.e. patients with central venous catheters and/or immunosuppressive therapies added a broad-spectrum antibiotic therapy. It is essential identify risk factors for attributable mortality and set up stewardship programme improve infection management. <h3>Purpose</h3> The objective this study was compare clinical outcomes candidaemia...

Ever since the late 1970s, occupational exposure associated with handling of antineoplastic drugs (ADs) in healthcare environment has been highlighted and demonstrated. Contamination was detected both operating rooms (OR) compounding units (CU), where workers handle are exposed to ADs different ways. In OR, risk is higher staff receives less training than CU. This study aimed assess compare knowledge practices about safe by caregivers working these two locations, namely CU OR.Two...

Abstract The occupational exposure of caregivers to antineoplastic agents has been demonstrated since 1979. Since the early 1990s, numerous studies from several countries have contamination care facilities by drugs. As it is easier sample, most measurements in workers are carried out urine sample. distribution and elimination half‐lives irinotecan suggest that blood can be considered as better than for biomonitoring a potential healthcare workers. We describe here development validation...

<h3>Background</h3> Despite the benefits of antibiotic re-evaluation (decrease in emergence bacterial resistance, adverse effects and costs) physicians do not systematically trace it. In our hospital, after implementation June 2013 a day-2 (AR) module prescription software three awareness periods prescribers, only 53% AR were done for 10 high-risk antibiotics. <h3>Purpose</h3> The aim this work was to study feasibility follow-up by pharmacy re-evaluation. <h3>Material methods</h3> All...

<h3>Background</h3> A first preliminary study conducted in 2017 among the mothers of a postpartum unit showed that 82% medication administrations were not traced electronic medical chart. In this unit, for women postvaginal delivery only, midwives ensure patient management and prescribe basic pain medication, which are self-managed by mother. These results reveal insufficient traceability unit. <h3>Purpose</h3> To evaluate professional practices before after implementation safety procedures...

<h3>Background</h3> According to the ECDC, there are 1 24 000 cases of <i>Clostridium difficile</i> infection (CDI) and 3700 attributable deaths per year in Europe. In our hospital, an antimicrobial stewardship programme (ASP) was implemented 2015 with a multidisciplinary team. This preliminary study showed that only 23% prescriptions were initially agreement international recommendations. A 30% rate CDI relapse observed. <h3>Purpose</h3> The aim this evaluate acculturation prescribers...

<h3>Background</h3> Subcutaneous antipsoriatic biologic therapy (SCABT) facilitates ambulatory care. However, it requires a therapeutic education of patients (TEP) to enable acquire the necessary skills for proper use medications and ensure safe administration. <h3>Purpose</h3> The aim this study was improve patients' care management on SCABT. <h3>Material methods</h3> This work took place in dermatology unit (10 beds) university hospital. A patient nurse survey conducted during TEP sessions...