Lippia gracilis, popularly known in Brazil as 'alecrim-de-tabuleiro', is used for many purposes, especially antimicrobial and antiseptic activities. The leaves of three L. gracilis genotypes, including LGRA-106, LGRA-109 LGRA-110 were collected from the Active Germplasm Bank located "Campus Rural da UFS" research farm at São Cristóvão country, Sergipe State, Brazil. essential oils obtained plants by hydrodistillation. Chemical analysis was performed gas chromatography-mass spectrometry...

Female Wistar rats were exposed to filtered air (F) or concentrated fine particulate matter (P) for 15 days. After mating, the divided into four groups and again F P (FF, FP, PF, PP) beginning on day 6 of pregnancy. At embryonic 19, placenta was collected. The placental structure, protein gene expression TGFβ1, VEGF-A, its receptor Flk-1 RAS evaluated by indirect ELISA quantitative real-time PCR.Exposure decreased mass, size, surface area as well VEGF-A content. In maternal portion placenta,...

To evaluate the effect of hydroethanolic extract yacon on hyperglycemia induced by streptozotocin (STZ) in neonatal rats. Wistar rats aged two days old received an intraperitoneal injection STZ (160 mg/kg); after seven weeks, glycosuria was determined and animals with glucose levels above 250 mg/dL were included study. Groups diabetic non-diabetic treated orally at a dose 400 mg/kg/d for 14 d. Tests made phytochemical characterization, tolerance toxicity. The results showed that treatment...

The present study evaluated the effect of crude extract leaves Nectandra falcifolia (NEES) Castiglioni and its fractions in different experimental models inflammation (paw edema, pleurisy, ear edema). Carrageenan-induced edema paw pleurisy were Wistar rats (180—220 g), which treated with doses total (250, 500 mg·kg−1). Edema ear, induced by croton oil, determination myeloperoxidase activity Swiss mice (25—35 g). In this experiment, (Nf) (1.25, 2.5, 5.0, 7.5 mg) hexane, chloroform,...

This study aimed to evaluate the chemical composition of essential oils from three genotypes Lippia gracilis Schauer (Verbenaceae) and investigate cytotoxic activities these oils.Essential were extracted leaves using a Clevengertype apparatus, analysis was performed gas chromatograph coupled mass spectrometer flame ionization detector.3T3, MRC5, B16, HeLa, MCF-7 cell lines used in vitro cytotoxicity oils, level death determined 3-(4,5-dimethylthiazol-2-yl)-2,5diphenyltetrazolium bromide test...

The antinociceptive activity of the crude extract and fractions Stryphnodendron adstringens (Martius) Coville (barbatimão) was evaluated. Three experimental models pain induction were used: abdominal writhing, formalin, hot plate. results demonstrated an effect barbatimão in writhing induced by acetic acid formalin. However, extracts did not significantly alter latency time on plate mice. These suggest that has a peripheral effect.

Coriandrum sativum L. (Umbelliferae), conhecido popularmente por coentro, é uma planta doméstica cultivada nas diversas partes do mundo, inclusive no Brasil. As folhas e frutos coentro são utilizados como condimento em culinária na medicina popular analgésica, antirreumática, carminativa colagoga. O objetivo deste estudo foi avaliar o efeito tratamento com óleo essencial (OEC) extrato hidroalcóolico (EHC) modelos experimentais de inflamação roedores. A atividade antiinflamatória avaliada...

The aim of this work was to evaluate the antifungal activity essential oils (EOs) Lippia gracilis and sidoides accessions, their major compounds nanoemulsions. Nanoemulsions with 18% EO or compound were produced by spontaneous emulsification method. two L. accessions (LGRA-106 LGRA-109) (LSID-102 LSID-104) extracted hydrodistillation thymol carvacrol purchased commercially. Antifungal tested against Lasiodiplodia theobromae calculating percentage inhibition mycelial growth caused different...

This study aimed to characterize the chemical diversity of essential oils 37 Croton tetradenius plants grown in municipalities state Sergipe, Brazil, as well evaluate their antibacterial activities. Twenty-five compounds were identified C. tetradenius, and low variation was observed among studied. Monoterpenes, such α-pinene, α-terpinene, p-cymene, 1,8-cineole, trans-pinocarveol, camphor, pinocarvone, cis-ascaridole trans-ascaridole detected major compounds. The Cluster Analysis revealed two...

Summary Twenty‐eight Candida albicans strains obtained from women with vaginal candidiasis were tested for phospholipase and proteinase production clustered by multilocus enzyme electrophoresis (MLEE). The proteolytic phospholipidic activity considered moderate (0.56 ± 0.12 mm 0.53 0.09 mm, respectively) all isolates. isoenzymes malate dehydrogenase (MDH) sorbitol (SDH) showed strong intra‐specific discriminatory power. numerical genetic interpretation of the bands produced presented similar...

A phytochemical study of the ethyl acetate fractions from partition seeds and roots methanol extracts Cenchrus echinatus L. led to isolation three resveratrol-derived stilbenoids: pallidol (1), carasiphenol C (2) nepalensinol B (3). The results a topic anti-inflammatory evaluation, DPPH assay antiproliferative activity against adenocarcinoma cells (Caco 2) are described.

This work aimed to evaluate the in vitro antifungal activity of essential oils L. alba belonging carvone chemotype (LA-13 and LA-57) citral (LA-10, LA-29, LA-44); enantiomers (R)-(-)-carvone (S)-(+)-carvone; on phytopathogenic fungi Lasiodiplodia theobromae (LT), Fusarium pallidoroseum (FP) solani (FS).Concentrations 0.01; 0.05; 0.1; 0.2; 0.3; 0.5 1.0 mL/100 mL were tested, percentage mycelial growth inhibition (MGI) was calculated after 96h relation control.Minimal Inhibitory Concentrations...

This study aimed to evaluate the phenotypic and genotypic performance of basil (Ocimum basilicum L.) hybrids cultivars, grown in four crop years, municipality São Cristóvão, state Sergipe.The following variables were evaluated: dry weight aerial part; essential oil content yield; contents linalool, 1,8-cineol, neral, geranial, methyl cinnamate.Five ('Sweet Dani' x 'Maria Bonita', 'Genovese' 'Cinnamon' 'Sweet 'Cinnamon', 'Genovese') parent cultivars ('Maria Dani', 'Genovese', 'Cinnamon')...

The anti-inflammatory effect of an ethanol extract Helicteres gardneriana (Nees) Castiglioni was assayed in experimental models pleurisy and microcirculation situ. Treatment animals with 500 mg/kg body weight reduced the exudate volume (35% reduction) induced by intrapleural injection carrageenan migration polymorphonuclear cells into inflamed pleural cavity rats (40%). Additionally, rolling adhesion leukocytes number that migrated toward perivascular space response to were decreased (500...

Lippia gracilis, popularly known in Brazil as ‘alecrim-de-tabuleiro’, is used for many purposes, especially antimicrobial and antiseptic. The drying process of aromatic medicinal plants aims to minimize the loss active principles slow their deterioration, which may greatly influence yield chemical composition some species. objective this study was evaluate effect times (0, 2, 4, 8 days) on content essential oil L. gracilis accessions LGRA-106, LGRA-109, LGRA-201. leaves were dried at 40 oC,...

Soybeans have been of interest researchers because the presence isoflavones, a subclass flavonoids, which demonstrated anti-inflammatory activity. The aim this study was investigate activity methanol fraction from soybean, contains mainly isoflavone glucosides and malonylglucosides. soybean studied using croton oil–induced mouse ear edema carrageenan-induced pleurisy models. inhibited in dose-dependent manner: 0.625 mg/kg by 44.23% (P<.05), 1.25 60.68% (P<.01), 2.5 65.68% (P<.01)....

The seeds of Bixa orellana are used in popular medicine as a hypolipidemic drug. This study evaluated the antilipidemic activity of ethanolic and hexane extracts from of B. orellana in dyslipidemic rats. Dyslipidemia was induced by an intraperitoneal injection Triton WR1339 male Wistar animals were treated with extracts orellana. Plasma levels triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL-C), low-density (LDL-C), alanine aminotransferase (ALT) aspartate (AST)...