A5033198954- Agricultural Science and Fertilization
- Rheumatoid Arthritis Research and Therapies
- Antibiotic Resistance in Bacteria
- Rice Cultivation and Yield Improvement
- Salmonella and Campylobacter epidemiology
- Animal Genetics and Reproduction
- Systemic Lupus Erythematosus Research
- Global Cancer Incidence and Screening
- Plant Disease Resistance and Genetics
- Lymphoma Diagnosis and Treatment
- Water Quality and Pollution Assessment
- Plant Pathogens and Fungal Diseases
- Viral gastroenteritis research and epidemiology
- Weed Control and Herbicide Applications
- Heavy metals in environment
- Genetically Modified Organisms Research
- Streptococcal Infections and Treatments
- Agricultural Economics and Practices
- Antibiotics Pharmacokinetics and Efficacy
- 3D Printing in Biomedical Research
- Potato Plant Research
- Supramolecular Self-Assembly in Materials
- Bacterial Identification and Susceptibility Testing
- Agronomic Practices and Intercropping Systems
- Neuroendocrine Tumor Research Advances
Government Medical College and Hospital
2004-2025
Roswell Park Comprehensive Cancer Center
2025
Chhatrapati Shahu Ji Maharaj University
2015-2024
Government Medical College and Hospital
2004-2024
Agency for Science, Technology and Research
2021-2024
Bioinformatics Institute
2024
Singapore Institute for Clinical Sciences
2021-2024
Comer Children's Hospital
2024
University of Science and Technology, Meghalaya
2024
Indian Institute of Technology Roorkee
2024
The N6-methyladenosine (m6A) RNA modification is an important regulator of gene expression. m6A deposited by a methyltransferase complex that includes methyltransferase-like 3 (METTL3) and 14 (METTL14). High levels METTL3/METTL14 drive the growth many types adult cancer, inhibitors are emerging as new anticancer agents. However, little known about epitranscriptome or role in neuroblastoma, common pediatric cancer. Here, we show METTL3 knockdown pharmacologic inhibition with small molecule...
Abstract Background Chickpea ( Cicer arietinum L.) is an economically important cool season grain legume crop that valued for its nutritive seeds having high protein content. However, several biotic and abiotic stresses the low genetic variability in chickpea genome have continuously hindered molecular breeding programs. STMS (Sequence Tagged Microsatellite Sites) markers which are preferred construction of saturated linkage maps species, also emerged as most efficient reliable source...
A retrospective study of bacterial isolates from cases neonatal septicemia was undertaken over a period 5 years (July 1998 - June 2003) at the Government Medical College Hospital, Chandigarh, India. The carried out to determine profile, antimicrobial susceptibility isolates, and change in trends period. total 3,064 blood samples for culture were obtained, which 588 positive isolates. Most detected by occurred first week life (64.4%). Gram-negative bacilli (58.5%) predominated Gram-positive...
Bloodstream infections are associated with significant patient morbidity and mortality worldwide. In this study, we examined antimicrobial susceptibility patterns by reviewing the data on 5,704 blood samples that were collected from patients fever/sepsis admitted to Government Medical College Hospital, Chandigarh, India, over a period of 1 year August 2003 July 2004. Among 567 qualifying samples, Pseudomonas aeruginosa (19.75%), Escherichia coli (15.17%), Klebsiella pneumoniae (14.99%),...
A biocompatible hydrogel containing a hexapeptide as key unit has been designed and fabricated. Our design construct comprises β-sheet-rich short in the center with hydrophobic long chain hydrophilic triple lysine attached at N- C-terminals, respectively. Thus, it is this amphiphilic nature of molecule that facilitates gelation. It can capture solvent molecules three-dimensional cross-linked fibrillar networks. The character modulated to produce an excellent soft material for inhibition...
Brain injury can lead to the loss of neuronal functions and connections, along with damage extracellular matrix (ECM). Thus, it ultimately results in devastating long-term damage, recovery from this is a challenging task. To address issue, we have designed sulfo-group-functionalized injectable biocompatible peptide hydrogel, which not only mimics ECM supports damaged neurons but also releases neurotrophic factor around injured sites brain presence metalloproteinase 9 (MMP9) enzyme. It has...
This study develops a Bayesian semi-parametric model to examine the longitudinal growth and appetite phenotypes in children from GUSTO cohort, with focus on understanding relationship between eating behaviours outcomes over time. While behaviours, such as picky eating, have been shown influence future weight obesity risk, their developmental patterns associations trajectories remain under-explored. work addresses these gaps by modelling data, including both metrics (e.g., BMI) Child Eating...
Objectives Human immunodeficiency virus (HIV) is one of the most dreadful infections worldwide. Although common mode transmission unprotected sex in India, threat parent-to-child (PTCT) serves as a major roadblock curbing infection. The study was conducted to decipher trends PTCT at tertiary care centers North India. Materials and Methods This prospective over 8 years, wherein all pregnant women (19,996) attending antenatal clinics were included study. Testing done free cost, following...
Background: Breast cancer screening for women less than 40 years old is practically non-existent. Since can detect at an early stage, not having a surveillance guideline breast in younger result detection of the advanced stages. The purpose this study was to investigate incidence and behavior women. Methods: Surveillance, Epidemiology End Results (SEER) registry data from 2004 2014 were accessed study. All diagnosed with complete information included further divided into two groups based on...
A multiarm nanomedicine template has been designed following bottom-up approach, which target neuropilin-1 (Nrp-1) receptor of cancer cells. Through this venture, we discovered that cucurbit [6] uril (CB [6]) binds with tubulin close to binding pocket vinblastine site and perturbs polymerization. To increase the specificity gold nanoparticle (GNP) toward Nrp-1-rich cells, further modified GNP Nrp-1 receptor-specific short peptide (CGNKRTR). Remarkably, found an interesting self-assembly...