A5056628600- Microtubule and mitosis dynamics
- Protist diversity and phylogeny
- Case Reports on Hematomas
- Infectious Diseases and Tuberculosis
- Genetic and Kidney Cyst Diseases
- Spinal Hematomas and Complications
- Orthopedic Infections and Treatments
- Micro and Nano Robotics
- Hippo pathway signaling and YAP/TAZ
- Cerebrospinal fluid and hydrocephalus
- Mitochondrial Function and Pathology
- DNA Repair Mechanisms
- Spinal Cord Injury Research
- Abdominal Surgery and Complications
- Spine and Intervertebral Disc Pathology
- Cervical and Thoracic Myelopathy
- Microbial Community Ecology and Physiology
- Pneumothorax, Barotrauma, Emphysema
- Tuberculosis Research and Epidemiology
- Spinal Dysraphism and Malformations
- Genetic Neurodegenerative Diseases
- Spinal Fractures and Fixation Techniques
- Trauma Management and Diagnosis
Indian Spinal Injuries Centre
2024
Yashoda Hospital
2024
Vardhman Mahavir Medical College & Safdarjung Hospital
2024
Spinal Injuries Center
2023
Max Super Speciality Hospital
2023
Safdarjang Hospital
2021
University of Georgia
2016-2019
Cilia, essential motile and sensory organelles, have several compartments: the basal body, transition zone, middle distal axoneme segments. The segment accommodates key functions, including cilium assembly activities. While contains doublet microtubules (incomplete B-tubules fused to complete A-tubules), only A-tubule extensions, its existence requires coordination of microtubule length at nanometer scale. We show that three conserved proteins, two which are mutated in ciliopathy Joubert...
Motile cilia generate directed hydrodynamic flow that is important for the motility of cells and extracellular fluids. To optimize flow, motile are organized oriented into a polarized array. Basal bodies (BBs) nucleate position at cell cortex. Cytoplasmic BB-associated microtubules conserved structures extend from BBs. By using ciliate, Tetrahymena thermophila, combined with EM-tomography light microscopy, we show BB-appendage assemble coincidently new BB assembly they attached to These...
Abstract Ciliates divide by tandem duplication, a developmental process that remodels the parental cell into two daughters aligned head-to-tail. Here, Jiang et al. investigate elo1-1 mutation in Tetrahymena causes division plan to form too close.... In single cell, ciliates maintain complex pattern of cortical organelles are arranged along anteroposterior and circumferential axes. The underlying molecular mechanisms intracellular formation largely unknown. mutant thermophila, segmentation...
Ciliates such as Tetrahymena thermophila have two distinct nuclei within one cell: the micronucleus that undergoes mitosis and meiosis macronucleus amitosis, a type of nuclear division does not involve bipolar spindle, but still relies on intranuclear microtubules. provide an opportunity for discovery factors specifically contribute to chromosome segregation based by identification affect micronuclear macronuclear division. Kinesin-14 is conserved minus-end directed microtubule motor...
ABSTRACT Motile cilia generate directed hydrodynamic flow that is important for the motility of cells and extracellular fluids. To optimize flow, motile are organized oriented into a polarized array. Basal bodies (BB) nucleate position at cell cortex. Cytoplasmic BB-associated microtubules conserved structures extend from BBs. Using ciliate, Tetrahymena thermophila , combined with EM-tomography light microscopy, we show BB-appendage assemble coincident new BB assembly attached to These...
Spinal adhesive arachnoiditis is a rare occurrence with diverse etiology. The clinical picture not universal, and varying degrees of neurodeficit have been mentioned. Spontaneous spinal cord herniation or idiopathic occurs due to displacement the through dural arachnoid defect. We report case 29-year-old male paraplegic patient nontraumatic injury (SCI) following surgery for an intradural extramedullary lesion at T10-T11 level who developed loss truncal balance after two years index surgery....
Introduction: Spinal tuberculosis (TB) is the most common form of skeletal tuberculosis. Paradiscal continuous vertebral involvement at a single level prevalent pattern among all forms spinal TB. There wide range reported incidences multiple-level non-contiguous TB in literature. We would like to discuss on utility whole spine screening T2-weighted (T2W) mid-sagittal magnetic resonance imaging (MRI) film diagnosing and therapeutic benefits it can provide. Methods: have done retrospective...
Occurrence of hemorrhagic cyst inside ligamentum flavum is a very rare phenomenon and presents with back pain, radiculopathy, or neurogenic claudication. Various causes reported in the literature are trauma, anticoagulant therapy, increased micromotion setting unstable degenerated motion segment.
Symptomatic spinal epidural hematoma (SEH) is a rare but well-documented complication in spine surgery, often associated with risk factors such as abnormal coagulation parameters, low platelets, excessive bleeding, and inadequate hemostasis. While bilateral SEH frequently described the literature, unilateral following surgery seldom reported. We present unique case of neurological deficit resulting from an midline-sparing due to drain placement 80-year-old male patient without comorbidities...