A5043660624- Pregnancy and preeclampsia studies
- Endometrial and Cervical Cancer Treatments
- MRI in cancer diagnosis
- Fetal and Pediatric Neurological Disorders
- Maternal and fetal healthcare
- Uterine Myomas and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Prenatal Screening and Diagnostics
- Endometriosis Research and Treatment
- Ovarian cancer diagnosis and treatment
- COVID-19 Impact on Reproduction
- Ectopic Pregnancy Diagnosis and Management
- Urological Disorders and Treatments
- Abdominal Trauma and Injuries
- Testicular diseases and treatments
- Congenital heart defects research
- Coronary Artery Anomalies
- Atomic and Subatomic Physics Research
- COVID-19 and healthcare impacts
- Urologic and reproductive health conditions
- Cervical Cancer and HPV Research
- Congenital Heart Disease Studies
- Pediatric Urology and Nephrology Studies
- Neonatal and fetal brain pathology
Policlinico Umberto I
2021-2024
Sapienza University of Rome
2021-2024
High- and low-risk endometrial carcinoma (EC) differ in whether or not a lymphadenectomy is performed. We aimed to develop MRI-based radio-genomic models able preoperatively assess lymph-vascular space invasion (LVSI) discriminate between low- high-risk EC according the ESMO-ESGO-ESTRO 2020 guidelines, which include molecular risk classification proposed by “ProMisE”. This retrospective, multicentric study that included 64 women with who underwent 3T-MRI before hysterectomy. Radiomics...
Abstract Purpose Introduce DWI and quantitative ADC evaluation in O-RADS MRI system observe how diagnostic performance changes. Assess its validity reproducibility between readers with different experience female pelvic imaging. Finally, evaluate any correlation value histotype malignant lesions. Materials Methods In total, 173 patients 213 indeterminate adnexal masses (AMs) on ultrasound were subjected to examination, from which 140 172 AMs included the final analysis. Standardised...
To evaluate the potential of Intravoxel Incoherent Motion (IVIM) Imaging in quantification placental micro-perfusion and microstructural features to identify discriminate different forms intrauterine growth restriction (IUGR) normal fetuses pregnancies.Small for gestational age SGA (n = 8), fetal FGR 10), 49) pregnancies were included study. Placental Magnetic Resonance (MRI) was performed at 1.5 T using a diffusion-weighted sequence with 10 b-values. IVIM fractional perfusion (fp),...
Background Perfusion and diffusion coexist in the placenta can be altered by pathologies. The two‐perfusion model, where f 1 and, 2 are perfusion‐fraction of fastest slowest perfusion compartment, respectively, D is coefficient, may help differentiate between normal impaired placentas. Purpose Investigate potential IVIM model differentiating abnormal Study‐Type Retrospective, case–control. Population 43 pregnancy, 9 fetal‐growth‐restriction (FGR), 6 small‐for‐gestational‐age (SGA), 4...
Structured reporting systems for endometriotic disease are gaining a central role in diagnostic imaging: our aim is to evaluate applicability and the feasibility of recent ENZIAN score (2020) assessed by MRI. A total 60 patients with suspected tubo-ovarian/deep endometriosis were retrospectively included study according following criteria: availability MR examination; histopathological results from laparoscopic or surgical treatment; not assuming estro-progestin progestin therapy. Three...
Background: Congenital heart diseases (CHDs) are often associated with significant neurocognitive impairment and neurological delay. This study aims to elucidate the correlation between type of CHD Doppler velocimetry investigate possible presence fetal brain abnormalities identified by magnetic resonance imaging (MRI). Methods: From July 2010 2020, we carried out a cross-sectional 63 singleton pregnancies diagnosis different types complex CHD: LSOL (left-sided obstructive lesions; RSOL...
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been a major global health problem since December 2019. This work aimed to investigate whether pregnant women's mild and moderate SARS-CoV-2 infection was associated with microstructural vascular changes in the placenta observable vivo by Intravoxel Incoherent Motion (IVIM) at different gestational ages (GA). retrospective, nested case-control of women during pandemic (COVID-19 group, n = 14) compared pre-pandemic healthy...
INTRODUCTION: Endometriosis affects 10%-15% of women in reproductive age and may cause no-cyclic chronic pelvic pain, dysmenorrhea, dyspareunia, urinary tract symptoms, it is frequently associated with infertility. The peak incidence between 24 29 years old the clinical diagnosis endometriosis generally delayed by 6-7 years. Laparoscopy surgical biopsies "gold standard" for endometriosis, histological verification endometrial ectopic glands and/or stroma. However, nowadays two different...
The placenta may incur several pathologies during fetal growth due to perfusion impairment such as Fetal-Growth-Restriction (FGR) and the accretism. Two-perfusion IVIM model (with f1, D1*, f2, D*2 D parameters) were used fit data. DWIs corrected for distributed noise χ. Mean-values differences of quantified parameters in diseased healthy placentas analyzed by ANOVA test. slower f2 fraction associated with trophoblastic was significantly lower FGR compared normal placenta, whereas faster...
Motivation: Currently, no study has investigated the role of diffusion-MRI to assess placenta women getting SARS-CoV-2 infection. Goal(s): To placental tissues abnormalities due Approach: Pregnant COVID-19 group (n=14) and pre-pandemic healthy (n=19) were using IVIM protocol at 1.5T. Results: D was significantly higher in compared that age-matched group. No-significant difference between f values found two groups suggesting no-specific microstructural damage with no-perfusion alteration. A...