A5080196425- Congenital Heart Disease Studies
- Birth, Development, and Health
- Congenital Diaphragmatic Hernia Studies
- Head and Neck Cancer Studies
- Pregnancy and preeclampsia studies
- Congenital heart defects research
- RNA modifications and cancer
- Tracheal and airway disorders
- Cardiovascular and Diving-Related Complications
- Lung Cancer Treatments and Mutations
- Epigenetics and DNA Methylation
- Pectus Deformity Diagnosis and Treatment
- Cardiac Valve Diseases and Treatments
- Cancer-related gene regulation
- Management of metastatic bone disease
- Vascular anomalies and interventions
- Radiomics and Machine Learning in Medical Imaging
- Phonocardiography and Auscultation Techniques
- Health, Environment, Cognitive Aging
- Air Quality and Health Impacts
- Aortic Disease and Treatment Approaches
- Health disparities and outcomes
- Direction-of-Arrival Estimation Techniques
- Hip disorders and treatments
- Liver Disease and Transplantation
Chongqing Medical University
2024-2025
Children's Hospital of Zhejiang University
2012-2025
Zhejiang University
2002-2025
National Clinical Research
2025
Jiangxi University of Traditional Chinese Medicine
2025
Jiangsu University of Science and Technology
2025
Children's Hospital of Chongqing Medical University
2025
Hangzhou Medical College
2024
Second People's Hospital of NanTong
2024
Nantong University
2024
N 6-methyladenosine (m6A) modification of RNA is deposited by the methyltransferase complex consisting Mettl3 and Mettl14 erased demethylase Fto Alkbh5 involved in diverse biological processes. However, it remains largely unknown specific function mechanism regulating adult neural stem cells (aNSCs). In present study, utilizing a conditional knockout (cKO) mouse model, we show that ablation aNSCs transiently increases proliferation promotes neuronal differentiation both vitro vivo, but long...
Background Developmental dysplasia of the hip (DDH) is a common orthopedic disease in children. In clinical surgery, it essential to quickly and accurately locate exact position lesion, there are still some controversies relating DDH status. We adopt artificial intelligence (AI) solve above problems. Methods this paper, automatic measurements classifications were achieved using three-stage pipeline. first stage, we used Mask-RCNN detect local features image segment bony pelvis, including...
Background: Congenital heart disease (CHD) is a common birth defect in children. Intelligent auscultation algorithms have been proven to reduce the subjectivity of diagnoses and alleviate workload doctors. However, development this algorithm has limited by lack reliable, standardized, publicly available pediatric sound databases. Therefore, objective research develop large-scale, high-standard, high-quality, accurately labeled congenital database, perform classification tasks evaluate its...
To report the treatment outcomes and complication rates of stereotactic radiotherapy in management patients with juxtapapillary choroidal melanoma.A retrospective review 64 consecutive melanoma, located within 2 mm optic disc, treated at Princess Margaret Hospital between October 1998 January 2006.The median age was 63 years. The tumour height 4.2 mm, largest basal diameter 9.8 mm. prescribed radiation dose 70 Gy five fractions over 10 days, follow-up 37 months. Post-treatment, actuarial...
The coronavirus disease 2019 (COVID-19) has caused a global pandemic. All people including children are generally susceptible to COVID-19, but the condition is relatively mild for children. diagnosis of COVID-19 largely based on epidemiological evidence and clinical manifestations, confirmed by positive detection virus nucleic acid in respiratory samples. main symptoms fever cough; total number white blood cell count usually normal or decreased; chest imaging characterized interstitial...
Abstract Zinc-based alloys have attracted increasing interest as absorbable implant metals due to their suitable degradation rate and biocompatibility. However, a high concentration of Zn 2+ the process results in cytotoxicity, low osteogenesis remains problem. In this work, compact coating well integrated into substrate was fabricated on surface zinc via micro-arc oxidation (MAO). The is mainly composed ZnO. addition phosphate reinforced adhesive strength between coating. Electrochemical...
Zinc plays a critical role in cellular functions, but its excess may lead to detrimental effects, including cardiac abnormalities. The impact of zinc overload on cardiomyocytes is investigated this study. For the first time, we report regulatory relationship between and histone acetylation. Excessive downregulates transcription Bmp4 HL-1 cell line primary cardiomyocytes. This downregulation linked reduced acetylation (H3K9ac), mediated by suppression acetyltransferases (HATs), rather than...
This investigation assesses the perinatal risks associated with different clinical subtypes of intrahepatic cholestasis pregnancy (ICP) based on symptomatology, goal informing optimal delivery timing for each specific ICP subtype. The retrospective study encompassed 2,057 singleton pregnancies ICP, categorized into single-symptomatic (ICP-S) and multisymptomatic (ICP-M) groups. ICP-M group was further subdivided symptom combinations: elevated TBA transaminases (ICP-MT), pruritus (ICP-MP),...
Background A good prognosis of congenital heart disease (CHD) depends on early diagnosis and intervention. Under the current screening conditions, a significant proportion still go undetected. Metabolomics, as phenotype‐correlated research methodology, remains underused in study CHD, which could provide possibility to screen neonatal CHD efficiently. Methods Data for analysis are from >22 000 neonates captured Network Platform April 2020 November 2021 11 cities China. After data matching...
Abstract Background Globally, common gynecological disorders such as Polycystic Ovary Syndrome (PCOS), endometriosis, uterine fibroids (non-malignant diseases), well cervical cancer, and ovarian cancer (gynecological cancers), profoundly impact women’s physical mental health. The burden of these diseases exhibits significant geographical disparities across different countries regions, making a comprehensive precise assessment the global particularly crucial. Such an will facilitate...
Mandarin fruit detection provides crucial technical support for yield prediction and the precise identification harvesting of mandarin fruits. However, challenges such as occlusion from leaves or branches, presence small partially visible fruits, limitations in model efficiency pose significant obstacles a complex orchard environment. To tackle these issues, we propose ELD-YOLO, lightweight framework designed to enhance edge detail preservation improve occluded Our method incorporates...