A5061886468- Antibiotic Use and Resistance
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Antibiotics Pharmacokinetics and Efficacy
- HIV/AIDS drug development and treatment
- HIV-related health complications and treatments
- Innovations in Medical Education
- HIV Research and Treatment
- Sepsis Diagnosis and Treatment
- Social Media in Health Education
- Bacterial Identification and Susceptibility Testing
- Hepatitis C virus research
- Antifungal resistance and susceptibility
- Respiratory viral infections research
- Fungal Infections and Studies
- Brucella: diagnosis, epidemiology, treatment
- Appendicitis Diagnosis and Management
- Healthcare cost, quality, practices
- Academic Publishing and Open Access
- Clinical Reasoning and Diagnostic Skills
- Vaccine Coverage and Hesitancy
- Long-Term Effects of COVID-19
- HIV/AIDS Research and Interventions
- COVID-19 epidemiological studies
- Bone and Joint Diseases
The University of Texas Southwestern Medical Center
2015-2025
Southwestern Medical Center
2019-2024
VA North Texas Health Care System
2014-2021
Dallas VA Medical Center
2021
Parkland Health & Hospital System
2021
Office of Infectious Diseases
2017
HomeCirculationVol. 144, No. 6In-Depth Evaluation of a Case Presumed Myocarditis After the Second Dose COVID-19 mRNA Vaccine Free AccessCase ReportPDF/EPUBAboutView PDFView EPUBSections ToolsAdd to favoritesDownload citationsTrack citationsPermissionsDownload Articles + Supplements ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toSupplemental MaterialFree ReportPDF/EPUBIn-Depth Alagarraju Muthukumar, Madhusudhanan Narasimhan, Quan-Zhen Li, Lenin Mahimainathan, Imran Hitto, Franklin...
Background NRTI-sparing regimens may avoid long-term mitochondrial, bone and renal toxicities maintain viral suppression. Methods In the RADAR study, 85 antiretroviral-naïve HIV-infected patients were randomized to receive either raltegravir (RAL) (n = 42) or tenofovir/emtricitabine (TDF/FTC) 43), each with ritonavir-boosted darunavir (DRV/r). Virologic efficacy was assessed at weeks 24 48. Bone mineral density (BMD) by dual energy X-ray absorptiometry (DXA) scan baseline week 48, turnover...
Abstract Background: Patients discharged from emergency departments (ED) with antibiotics for common infections often receive unnecessarily prolonged durations, representing a target transition of care (TOC) antimicrobial stewardship intervention. Methods: This study aimed to evaluate the effectiveness TOC pharmacists’ review on decreasing duration discharge oral in patients ED at an academic medical center. Pharmacist interventions were guided by antibiotic therapy guidance focused...
Both HIV and hepatitis C virus (HCV) infections are associated with higher osteoporotic fracture risk. Increased bone turnover, liver fibrosis, tenofovir (TDF) use or hormonal imbalances possible underlying mechanisms.This prospective, cross-sectional study assessed 298 male volunteers either virologically suppressed untreated HCV mono-infections, HIV/HCV co-infection noninfected controls.Study participants underwent mineral density (BMD) by dual-energy x-ray absorptiometry measurement of...
Journal clubs have been an enduring mainstay of medical education, and hosting these on social media platforms can expand accessibility engagement. We describe the creation impact #IDJClub, infectious diseases (ID) Twitter journal club.We launched #IDJClub in October 2019. Using account @IDJClub, ID physician leads a 1-hour open-access discussion recent publication. All participants use hashtag #IDJClub. Sessions started monthly, but increased due to demand during coronavirus disease 2019...
Brucellosis is recognized as a neglected zoonotic disease and major public health threat. The purpose of this study was to characterize epidemiological risk factors healthcare utilization compare clinical aspects among adult pediatric cases in North Texas.A retrospective chart review electronic medical records completed at 3 large tertiary centers-Parkland Health Hospital System, Clements University Hospital, Children's Medical Center-between January 1, 2007 June 2017. Demographic, clinical,...
Social media platforms have revolutionized how we consume information, along with to effectively present communication, education, and advocacy efforts. There is profound value in leveraging social within these aspects for the field of infectious diseases, divisions individual clinicians. Herein, provide rationale incorporate as a key competency diseases training specific guidance on education strategic development new accounts critical success.
Background Despite compelling evidence for activity against HIV-1 in vitro, a virologic effect of statins has not been shown clinical studies. Given their short plasma half-lives, such an may be transient and only apparent during ongoing exposure. Methods We studied all HIV infected US-Veterans who started HAART 1995–2011, had documented viral load (VL) >1000 copies/mL, reached undetectable VL on HAART, ≥1 follow-up within 13 months. defined failure (VF) as the first >1,000 copies/mL or 2...
Utilization of rapid diagnostic testing alongside intensive antimicrobial stewardship interventions improves patient outcomes. We sought to determine the clinical impact a blood culture identification (BCID) panel in an established Antimicrobial Stewardship Program (ASP) with limited personnel resources.A single center retrospective pre- and post-intervention cohort study was performed following implementation BCID on patients admitted at least 1 positive during period. The primary outcome...
Pharmacists and physicians play key roles in antimicrobial stewardship. This commentary on a case describes these health professionals' need to collaborate optimize therapeutic use of antimicrobials clinical settings. Prescription preauthorization is one stewardship strategy that can meet with some physicians' frustration generate conflict between pharmacists prescribing
Abstract Background In people living with HIV (PLWH), statins may be disproportionately effective but remain underutilized. A large prospective trial in patients low to moderate cardiovascular (ASCVD) risk will reveal whether they should considered all PLWH. But its effect size not apply real-world PLWH higher ASCVD and mortality risk. Also, the clinical role of non-statin lipid-lowering therapy (LLT) LLT adherence this population is unknown. Methods Comparative multi-level marginal...
Abstract Antimicrobial prescribing and the associated discipline of antimicrobial stewardship have inherent ethical moral dimensions. We contend that explicit, formal application principles frameworks can strengthen further justify value programs their work. To illustrate this process, we highlight 3 scenarios regularly encounter at prescriber, institutional, societal levels, analyze these using Beauchamp Childress biomedical ethics framework.
A 61-year-old female with a history of advanced HIV disease and chronic hepatitis B was presented an 8-week painful oral ulcers. She appeared systemically well but examination revealed multiple well-demarcated clean-based ulcers on the tongue hard palate. Biopsy one lesions showed numerous histiocytes containing intracellular yeast forms consistent Histoplasma capsulatum var. . Fungal blood cultures subsequently grew H. , confirming diagnosis disseminated histoplasmosis. treated intravenous...