A5100363407- Ferroelectric and Piezoelectric Materials
- Dielectric materials and actuators
- Acoustic Wave Resonator Technologies
- Traditional Chinese Medicine Studies
- Fungal and yeast genetics research
- Healthcare and Venom Research
- Diverse Approaches in Healthcare and Education Studies
- Microwave Dielectric Ceramics Synthesis
- Advanced Sensor and Energy Harvesting Materials
- Eosinophilic Disorders and Syndromes
- Pharmacological Effects of Natural Compounds
- Assisted Reproductive Technology and Twin Pregnancy
- Urticaria and Related Conditions
- Multiferroics and related materials
- Phytochemicals and Antioxidant Activities
- Thyroid and Parathyroid Surgery
- Pancreatic and Hepatic Oncology Research
- Plant Pathogens and Fungal Diseases
- Uterine Myomas and Treatments
- Immune Cell Function and Interaction
- Reproductive Health and Technologies
- Mycotoxins in Agriculture and Food
- Antioxidant Activity and Oxidative Stress
- T-cell and B-cell Immunology
- Technology and Data Analysis
Seoul National University Hospital
2024-2025
Seoul National University
2004-2023
Chungnam National University Hospital
2023
University of Central Florida
2022-2023
Florida College
2022-2023
Dong-A University
2022
Gachon University Gil Medical Center
2019
Seoul Social Welfare Graduate University
2017
Gachon University
2016
Chungbuk National University
2014-2015
Fusarium graminearum is an important plant pathogen that causes head blight of major cereal crops. The fungus produces mycotoxins are harmful to animal and human. In this study, a systematic analysis 17 phenotypes the mutants in 657 genes encoding putative transcription factors (TFs) resulted database over 11,000 (phenome). This provides comprehensive insights into how global significance regulates traits for growth, development, stress response, pathogenesis, toxin production...
Gibberella zeae is an ascomyceteous fungus that causes serious diseases in cereal crops. Severe epidemics require strains are virulent and can reproduce sexually. We characterized insertional mutant (designated ZH436) with a pleiotropic defect both traits, identified novel F-box protein gene encoding FBP1 (F-box 1) similar to fungal proteins including Saccharomyces cerevisiae Grr1, well-characterized component of the Skp1-Cullin-F-box (SCF(Grr1)) E3 ligase complex required for degradation....
ABSTRACT The sucrose nonfermenting 1 ( SNF1 ) protein kinase of yeast plays a central role in the transcription glucose-repressible genes response to glucose starvation. In this study, we deleted an ortholog from Gibberella zeae characterize its functions by using gene replacement strategy. mycelial growth deletion mutants (ΔGz was reduced 21 74% on diverse carbon sources. virulence ΔGz barley decreased, and expression encoding cell-wall-degrading enzymes reduced. most distinct phenotypic...
Porous lead zirconate titanate–lead zinc niobate (PZT–PZN) piezoelectric ceramics with a high degree of pore alignment were fabricated using directional freeze casting ceramic/camphene slurry. Well‐aligned pores formed as the replica camphene dendrites that grew in preferential orientation, while porosity 90% was achieved by employing low initial solid loading 5 vol%. As orientation angle to poling direction decreased, hydrostatic properties, such strain coefficient ( d h ), voltage g and...
Although advanced high-strength steel (AHSS) demonstrates excellent uniaxial tensile formability, its application in automotive parts is limited due to inferior flange formability. Despite extensive efforts enhance the formability of AHSS, our understanding it remains limited. In this study, we propose a novel approach hole expansion ratio (HER), which an indicator Firstly, correct existing misconception that HER does not correlate with It was verified through artificial neural network...
This study examines the effects of social pension reform on well-being older adults in Korea. Our provides an estimate impacts industrialized and urbanized context. We use monthly panel data from Household Income Expenditure Survey Korea Statistical Office. identify by utilizing exogenous variation benefit level generated 2014. apply a triple-differences approach to remove potential selection biases related program participation. The higher increases gross income. It does not decrease...
Background/Aims Ampullary tumors come in a wide variety of malignant forms. We evaluated the diagnostic accuracy endoscopy for ampullary tumors, and analyzed causes misdiagnosis. Methods compared endoscopic imaging biopsy results to final diagnoses. Types endoscope, numbers specimens taken, diagnoses were as possible factors influencing accuracy. Results Final 19 adenocarcinomas, 18 normal or papillitis, 11 adenomas, two adenomyomas, one paraganglioma, neuroendocrine tumor. The initial was...
Abstract CD4+CD25+ regulatory T cells are thought to be generated in the periphery as well thymus. We sought determine roles played by and transforming growth factor-β (TGF-β) induction maintenance of tolerance oral antigens BALB/c mice. found that administration a high dose ovalbumin (OVA) suppressed OVA-specific proliferation antibody production mice depleted CD25+ cells. In contrast, unresponsiveness induced lower doses OVA was only partially blocked CD25 depletion prior feeding....
Flextensional actuators composed of a piezoelectric PZN‐PZT layer and conducting PZN‐PZT/Ag were fabricated. Because the newly developed was sinterable at low temperature (<900°C), silver particles could be co‐fired with PZN‐PZT. Therefore, an electrically fabricated by mixing powder. When 30–50 wt% Ag mixed PZN‐PZT, resulting composites showed high‐electrical conductivity low‐densification mismatch respect to layer. The had approximately same resistivity as pure silver, because presence...
There is a growing interest in understanding the association between gut microbiota and inflammatory bowel disease (IBD). Natural compounds, such as Korean Red ginseng (KRG), show promise for IBD treatment because of their ability to influence microbiota. This study explored effects KRG on modulation subsequent intestinal epithelial cell regeneration an experimental colitis model. Using mouse model induced by 2 % dextran sodium sulfate, administered 200 or 400 mg/kg/day evaluate its...
Abstract Aim Patients who have undergone a cesarean section (CS) prior to hysterectomy are at higher perioperative risk of complications. The purpose this study was evaluate the safety total laparoscopic (TLH) in patients with CS. Methods We enrolled 482 treated TLH. Surgical outcomes including major complications were compared between without CS (no group; n = 324) and (prior 158). Major included vaginal cuff dehiscence, bowel, bladder, ureter great vessel injuries. Results complications,...
Emerging natural language processing (NLP) models have become more complex and bigger to provide sophisticated NLP services. Accordingly, there is also a strong demand for scalable flexible computer infrastructure support these large-scale, complex, diverse models. However, existing proposals cannot enough scalability flexibility as they neither identify nor optimize wide spectrum of performance-critical operations appearing in recent only focus on optimizing specific operations. In this...
치마버섯에서 추출한 베타글루칸을 Raw 264.7 세포에 처치한 후 MTT assay로 측정한 결과 베타글루칸 400 ㎍/㎖까지에 의한 세포독성은 없었다. 대식세포의 활성능을 측정하기 위해서 세포에서 NO와 TNF-α의 생성을 측정하였다. 대식세포에 24시간 처리한 대조군과 비교 시 TNF-α가 유의적으로 상승하였다. 이 베타글루칸이 대식세포인 세포를 활성화시키는 것으로 사료된다. 따라서 본 실험에 사용된 베타글루칸은 면역강화용 사료첨가제로서의 의미가 충분하다고 MDA-MB-231 유방암 세포의 성장을 저해하는지 확인하기 위하여 assay를 시행하였다. ㎍/㎖ 48시간 유방암세포의 성장이 억제하였다. 그리고 성장 억제 효과를 알아보기 위해 누드마우스에 접종하였다. 베타글루칸의 용량은 대조군(0 ㎍/mouse), 저용량(200 고용량(400 ㎍/mouse)으로 설정하여 경구투여 하였다. 저용량군(200 ㎍/mouse)이 고용량군 (400 ㎍/mouse)보다 항암효능이 더 많이...
Acute pancreatitis is one of the main causes intra-abdominal hypertension (IAH). IAH contributes to multiple physiologic alterations and leads development abdominal compartment syndrome (ACS) that induces multiorgan failure. We report a case ACS in patient with severe acute pancreatitis. A 44-year-old man who was admitted drunk state found have During management fluid resuscitation an intensive care unit, drowsy mentality, respiratory acidosis, shock requiring inotropes, oliguria developed...