- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Breast Implant and Reconstruction
- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Advanced Radiotherapy Techniques
- Cancer Treatment and Pharmacology
- Radiation Dose and Imaging
- Cancer Diagnosis and Treatment
- Genetic Neurodegenerative Diseases
- Brain Metastases and Treatment
- Cancer Risks and Factors
- Vascular Tumors and Angiosarcomas
- Cancer survivorship and care
- Health Systems, Economic Evaluations, Quality of Life
- Medical Imaging Techniques and Applications
- Cancer-related cognitive impairment studies
- Cancer Genomics and Diagnostics
- Economic and Financial Impacts of Cancer
- Advanced MRI Techniques and Applications
- Global Cancer Incidence and Screening
- Cardiac tumors and thrombi
- Sarcoma Diagnosis and Treatment
University of Washington
2013-2025
Fred Hutch Cancer Center
2023-2024
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa
2023
University of Washington Medical Center
2007-2023
Seattle University
2021
Seattle Cancer Care Alliance
2007-2019
Importance Postmastectomy radiation therapy (PMRT) improves local-regional disease control and patient survival. Hypofractionation (HF) regimens have comparable efficacy complication rates with improved quality of life compared conventional fractionation (CF) schedules. However, the use HF after mastectomy in patients undergoing breast reconstruction has not been prospectively examined. Objective To compare CF PMRT outcomes implant-based reconstruction. Design, Setting, Participants This...
ASCO Guidelines provide recommendations with comprehensive review and analyses of the relevant literature for each recommendation, following guideline development process as outlined in Methodology Manual . follow Conflict Interest Policy Clinical Practice other guidance (“Guidance”) provided by is not a or definitive guide to treatment options. It intended voluntary use clinicians should be used conjunction independent professional judgment. Guidance may applicable all patients,...
While breast radiotherapy typically includes regional nodal basins, the treatment of internal mammary nodes (IMN) has been controversial due to concern for long-term cardiac toxicity. For high risk patients where IMN is warranted, there limited data with regards degree heart sparing conferred by modern techniques. In this study, we sought analyze specific metrics deep inspiration breath hold (DIBH) in setting irradiation.From 2012 2015, 168 consecutive were treated adjuvant left-sided using...
Abstract Purpose To determine if dynamic contrast‐enhanced (DCE) magnetic resonance imaging (MRI) peak enhancement (PE) of primary breast cancer can predict the presence lymph node extracapsular extension (LNECE) in patients with axillary metastatic disease. Materials and Methods In all, 167 treated radiotherapy for invasive from January 1, 2006 to November 2007 were retrospectively identified. Patients DCE‐MRI surgical staging included this study. PE tumors was compared according nodal...
Objectives: Angiosarcoma is a rare complication of breast-conserving therapy. This study evaluated the change in incidence between 1992 and 2016 secondary breast angiosarcoma (SBA) patients with history cancer impact management strategies for original carcinoma on treatment. Methods: Breast cases were abstracted from Surveillance, Epidemiology, End Result (SEER) database. SBAs defined as angiosarcomas located occurring after prior diagnosis. Primary (PBAs) an diagnosis listed “one primary...
Abstract Breast multidisciplinary tumor boards (MTBs) play an important role in determining treatment. This article serves as a guide for the radiologist participating breast MTB, information presented at MTB can significantly influence treatment plans and dictate future steps further patient work-up. Multidisciplinary board preparation involves careful review of patient’s history while gathering all relevant imaging studies, reinterpreting them when appropriate. Presented images should be...
e12030 Background: The role of post-mastectomy radiation therapy (PMRT) after neo-adjuvant chemotherapy (NCT) in those with T3N0 disease, younger age, and different tumor subtypes is unclear. Methods: We conducted a single institution, retrospective analysis patients treated NCT mastectomy from 1985-2010. primary objectives were to (1) assess the association between PMRT long-term outcomes, (2) describe outcomes practice patterns based on subtype, pathologic response, age at diagnosis....
e12540 Background: Ductal carcinoma in situ (DCIS) is a common preinvasive breast cancer typically identified on screening mammography. Pure DCIS nonlethal, but 20-25% of cases core biopsy upstage to invasive at surgery and about half progress disease if not treated. As result, most patients undergo excision radiation therapy. score multigene assay that can aid treatment decision-making serve as surrogate marker ipsilateral recurrence (IBR) risk. Breast MRI accurately depict span has...
e12578 Background: Ductal carcinoma in situ (DCIS) is a preinvasive breast cancer typically excised and treated with adjuvant therapy. While there consensus that this results overtreatment, little agreement on who may avoid radiation or endocrine Two freely available prediction models, Van Nuys Prognostic Index (VNPI) Memorial Sloan Kettering Nomogram (MSK-N), are commonly used to identify low-risk DCIS based standard clinicopathological features. Oncotype newer commercially tissue-based...