A5083801746- Synthesis and biological activity
- Phenothiazines and Benzothiazines Synthesis and Activities
- Synthesis and Characterization of Heterocyclic Compounds
- Graphene and Nanomaterials Applications
- Nanoparticles: synthesis and applications
- Radiology practices and education
- Innovations in Medical Education
- Chromatin Remodeling and Cancer
- Cancer-related Molecular Pathways
- Cancer and Skin Lesions
- Thermal Regulation in Medicine
- Neurogenesis and neuroplasticity mechanisms
- 3D Printing in Biomedical Research
- Synthesis and bioactivity of alkaloids
- Breast Lesions and Carcinomas
- Alzheimer's disease research and treatments
- Student Assessment and Feedback
- Erythropoietin and Anemia Treatment
- Endometrial and Cervical Cancer Treatments
- Plant-based Medicinal Research
- Pharmacological Effects of Natural Compounds
- Advanced Nanomaterials in Catalysis
- Clinical Reasoning and Diagnostic Skills
- Iron Metabolism and Disorders
- Atherosclerosis and Cardiovascular Diseases
Taif University
2020-2025
King Salman Center for Disability Research
2025
Islamic University
2023-2024
King Fahd Medical City
2023-2024
Prince Mohammed bin Abdulaziz Hospital
2024
Imam Abdulrahman Bin Faisal University
2022-2024
Era's Lucknow Medical College and Hospital
2024
Kaolin clay-supported Zinc oxide (ZnO/KC) and ZnO NPs nanoparticles (NPs) were prepared by a chemical reduction process used for the photodegradation of methyl red (MR) dye as photocatalyst. Due to interlayered porous structure KC, we achieved an extremely good association between KC. The product confirmation was conducted Scanning electron microscopy (SEM), X-Ray diffraction (XRD), energy dispersive (EDX), Fourier transforms infrared (FTIR). SEM showed irregular morphology NPs, while ZnO/KC...
Pesticides play a crucial role in modern agriculture, aiding the protection of crops from pests and diseases. However, their indiscriminate use has raised concerns about potential adverse effects on human health environment. Pesticide residues food water supplies are serious hazards to general public since long-term exposure can cause cancer, endocrine disruption, neurotoxicity, among other problems. In response these concerns, researchers professionals have been exploring alternative...
Abstract Polymer-based nanocarriers are created from natural or synthetic polymers that modified to form submicroscopic particles. The polymer matrix can be customized provide specific properties, such as surface chemistry and flexibility. This allows the particles designed used in different fields. They promising nanomaterials therapeutic diagnostic agents, they have potential biomedical environmental applications. These engineered with other types of sizes, shapes, compositions. deliver...
Abstract: Adhatoda vasica (L.) (Acanthaceae) has essential therapeutic roles and is widely used in the indigenous medicine system or Ayurvedic of medicine. The important goals present study are to report in-silico anti-corona (COVID-19) activity different phytochemicals A. vasica. This will help find specific bioactive compounds, their use as anti- COVID-19 action for human welfare. chemical phytoconstituents with diverse pharmacological activities. These have been found active against many...
Systemic Lupus Erythematosus (SLE) is an autoimmune inflammatory condition affecting multiple systems. Cardiovascular morbidity a significant concern, with around 25% of SLE patients experiencing cardiac complications.
Objectives The aim of this study was to estimate the prevalence anemia among patients newly diagnosed with solid malignancies at King Faisal Hospital in Taif Province, Kingdom Saudi Arabia. Methods A descriptive, cross-sectional, hospital-based conducted from December 2017 March 2020. total 320 malignancy were examined assess prevalence. Results Of cancers, 245 (76.6%) female and 75 (23.4%) male. median (interquartile range) age 57 (45 ─ 66) years, range between 16 108 years. types cancer...
Abstract: In many significant bioactive heterocyclic compounds, the six-membered ring pyrimidines play a major role as components. There is lot of room for innovation in fields medicinal chemistry and chemical industries because numerous pyrimidine synthesis methods their varied reactions. The pharmacological effects derivatives include anticonvulsant, antibacterial, antifungal, antiviral, antitubercular, anticancer, antimicrobial, antihypertensive, antiulcer, anti-inflammatory,...
Methamphetamine, a highly addictive central nervous system (CNS) stimulant, is used worldwide as an anorexiant and attention enhancer. Methamphetamine use during pregnancy, even at therapeutic doses, may harm fetal development. Here, we examined whether exposure to methamphetamine affects the morphogenesis diversity of ventral midbrain dopaminergic neurons (VMDNs). The effects on morphogenesis, viability, release mediator chemicals (such ATP), expression genes involved in neurogenesis were...
This study aims to develop a nanodrug delivery system containing podophyllotoxin (PTOX), known anticancer drug, loaded on graphene oxide (GO). The system's ability inhibit α-amylase and α-glucosidase enzymes was also investigated. PTOX isolated from Podophyllum hexandrum roots with yield of 2.3%. GO, prepared by Hummer's method, converted into GO-COOH surface-mobilized using polyethylene glycol (PEG) (1:1) in an aqueous medium obtain GO-PEG. GO-PEG facile manner 25% loading ratio. All the...
Background: Due to the biological importance of benzoxazole derivatives, some 1- (benzo[d]oxazol-2-yl)-3,5-diphenyl-formazans 4a-f were synthesized and screened for in-silico studies in-vitro antibacterial activity. Methods: The benzo[d]oxazole-2-thiol (1) was prepared by reacting with 2-aminophenol carbon disulfide in presence alcoholic potassium hydroxide. Then 2-hydrazinylbenzo[d] oxazole (2) from reaction compound 1 hydrazine hydrate alcohol. Compound 2 reacted aromatic aldehydes give...
Abstract: The cinnoline nucleus is a bicyclic ring and an isosteric precursor to quinolone or isoquinoline. Cinnoline analogs are aromatic heterocyclic compounds having diverse therapeutic activities, such as antimicrobial, analgesic, anti-inflammatory, anti-tuberculosis, antimalarial, anticonvulsant, antioxidant, anticancer, antihypertensive, anti-anxiety, other activities. This attracting lot of attention in medicinal chemistry used structural subunit various with attractive chemical...
Background: Medical curriculum reform requires quality assurance in all curricular activities including assessment. Such necessitates a shift of focus from summative assessment (SA) to formative (FA). However, the implementation FA confronts several challenges that hinder its proper application, especially with increased number students and diversity required faculty members. Therefore, this study aims explore perception, implementation, facing members during application undergraduate...
Cervical cancer remains a major public health concern. The ratio of CD4+:CD8+ T-cells is used to evaluate the immune system function. This study aimed explore T-cell in relation glycemic status, inflammatory markers, vitamin D, and B12 patients with early diagnosed cervical cancer.This cross-sectional study. Blood samples were collected for flow cytometry analysis. Information regarding Papanicolaou (Pap) smears colposcopy investigations from 152 women type 2 diabetes admitted East Jeddah...
Nanotechnology holds significant ameliorative potential against neurodegenerative diseases, as it can protect the therapeutic substance and allow for its sustained release. In this study, reducing capping agents of Urtica dioica (UD), Matricaria chamomilla (MC), Murraya koenigii (MK) extracts were used to synthesize bio-mediated zinc oxide nanoparticles (ZnO-NPs) bacteria (Staphylococcus aureus Escherichia coli) rotenone-induced toxicities in D. melanogaster first time. Their optical...
Background Fever is a common presentation in pediatric age groups and the most reason for healthcare visits. Parents' knowledge essential early to facilities prevent possible complications. Studies suggest that febrile convulsions (FCs) often cause stress anxiety parents, who assume it may brain damage, future epilepsy attacks, mental retardation, physical injury, even death. This study aims assess knowledge, attitude, practices of FCs among parents. Methodology cross-sectional was conducted...
This study evaluates the seroprevalence of immunoglobulin M (IgM) and G (IgG) antibodies against SARS-CoV-2 after two doses Pfizer-BioNTech COVID-19 vaccination from women with breast cancer in Jazan city Kingdom Saudi Arabia, antibody detections were performed one month three months administration second dose.Overall, 103 patients included. Individuals who had vaccine, earlier diagnosed infection, not finalized immunization plan, or received dose recently excluded study. The detection test...
Pregabalin is a widely prescribed drug for various neurological disorders, yet its effects on embryonic cortical neuron development when given to pregnant women remain inadequately explored. In this study, we employed advanced three-dimensional (3D) culturing and in-house developed high-throughput robotic 3D bioprinting technologies evaluate their potential in neuropharmacology applications, using pregabalin as model compound. Using bioprinter tetrameric IIZK peptide hydrogel bioink, created...
Parkinson’s disease (PD) is a critical neurological disorder characterized by loss of voluntary motor control and substantial slowing movement. While traditionally attributed to environmental factors, recent studies underscore the significant role genetics in onset progression PD. This study aimed identify differentially expressed genes (DEGs) relevant pathways PD analyzing gene expression data from four datasets (83 53 substantia nigra samples) sourced Gene Expression Omnibus (GEO)...
Invasive breast cancer (BC) is a highly life-threatening disease affecting women world-wide. While its early identification may benefit the provision of more effective therapies, several BC-associated factors influence BC patients' therapeutic outcomes. Therefore, identifying novel prognostic and targets for invasive can help with accurate prognosis therapy-related decisions. The BRI3 binding protein (BRI3BP) gene was found to be principal in cohorts using artificial neural network (ANN)...