A5089798931- Emergency and Acute Care Studies
- Trauma and Emergency Care Studies
- Family and Patient Care in Intensive Care Units
- Cardiac Arrest and Resuscitation
- Nursing Roles and Practices
- Patient Safety and Medication Errors
- Simulation-Based Education in Healthcare
- Disaster Response and Management
- Nursing education and management
- Parkinson's Disease Mechanisms and Treatments
- Innovations in Medical Education
- Nursing Diagnosis and Documentation
- Pediatric Pain Management Techniques
- Healthcare professionals’ stress and burnout
- Clinical Reasoning and Diagnostic Skills
- Posttraumatic Stress Disorder Research
- Healthcare Decision-Making and Restraints
- Healthcare Policy and Management
- COVID-19 and Mental Health
- Nerve injury and regeneration
- Hormonal Regulation and Hypertension
- Interprofessional Education and Collaboration
- Infection Control in Healthcare
- Alzheimer's disease research and treatments
- Traumatic Brain Injury and Neurovascular Disturbances
Umeå University
2022-2025
Ambulance Care (Sweden)
2018-2025
Sophiahemmet University College
2021-2025
Karolinska Institutet
2015-2024
Turku University Hospital
2024
University of Turku
2024
Uppsala University
2007-2023
Stockholm South General Hospital
2012-2020
Stockholm Health Care Services
2018-2019
Helsinki University Hospital
2019
Inclusions of intraneuronal alpha-synuclein (α-synuclein) can be detected in brains patients with Parkinson's disease and dementia Lewy bodies. The aggregation α-synuclein is a central feature the pathogenesis. Among different species, large oligomers/protofibrils have particular neurotoxic properties should therefore suitable as both therapeutic diagnostic targets. Two monoclonal antibodies, mAb38F mAb38E2, high affinity strong selectivity for oligomers were generated. These which do not...
Patients undergoing radiotherapy for prostate cancer experience symptoms related to both the itself and its treatment, it is evident that patients with have unmet supportive care needs their disease. Over past decade, there has been an increase in amount of research within field mobile health use apps as tools managing illness. The main challenge develop a technology full potential being interactive real time. app Interaktor, which aims identify manage time includes (1) function patients'...
Objectives Non-conveyed patients represent a significant proportion of all cared for by ambulance services in the western world. However, scientific knowledge on non-conveyance is sparse. Therefore, aim this study was to describe prevalence non-conveyance, investigate associations and compare patients’ characteristics, drug administration, initial problems vital signs between non-conveyed conveyed patients. Design A population-based retrospective cohort study. Setting The setting area,...
Objectives To combat overcrowding in emergency departments, ambulance clinicians (ACs) are being encouraged to make on-site assessments regarding patients’ need for conveyance hospital, and this is creating new challenging demands ACs. This study aimed describe ACs’ experiences of assessing non-conveyed patients. Design A phenomenological interview based on a reflective lifeworld research approach. Setting The target area the was Stockholm, Sweden, which has population approximately 2.3...
Healthcare-associated infection caused by insufficient hygiene is associated with mortality, economic burden, and suffering for the patient. Emergency medical service (EMS) providers encounter many patients in different surroundings are thus at risk of posing a source microbial transmission. Hand (HH), proven control intervention, has rarely been studied EMS.
Due to its neurotoxic properties, oligomeric alpha-synuclein (α-syn) has been suggested as an attractive target for passive immunization against Parkinson's disease (PD). In mouse models of PD, antibody treatment shown lower the levels pathogenic α-syn species, including oligomers, although mechanisms action remain unknown. We have previously that astrocytes rapidly engulf oligomers are intracellularly stored, rather than degraded, resulting in impaired mitochondria.The aim present study was...
Paramedics' fatigue is rising. Stress factors show increased risk for burnout, fatigue, leaving the profession, decreased performance and patient safety. Meanwhile, paramedics' strong community of practice, autonomy a sense professional respect are important in forming psychological resilience. We aimed to explore Finnish perceptions job demands resources. Our study design was descriptive, inductive with constructivist approach. Using reflexive thematic analysis, we analyse open-ended...
Pathophysiological impairment of the neurovascular unit, including integrity and dynamics blood-brain barrier (BBB), has been denoted both a cause consequence neurodegenerative diseases. Pathological impact on BBB drug delivery also debated. The aim present study was to investigate transport, by determining unbound brain-to-plasma concentration ratio (Kp,uu,brain), in aged AβPP-transgenic mice, α-synuclein transgenic wild type mice. Mice were dosed with cassette five compounds, digoxin,...
Abstract Background Mental illnesses are increasing in the population; consequently, number of psychiatric emergencies handled by emergency medical services (EMS) has also increased. Alternative response systems have been developed and evaluated, but there is still a lack knowledge concerning patients' experiences being cared for EMS unit (In Swedish: Psykiatrisk Akut Mobilitet [PAM]). Objective The aim this study was to explore caring encounter with PAM team. Design A qualitative design 14...
Background The COVID-19 pandemic has accelerated the worldwide need for simple remotely delivered (digital) scalable interventions that can also be used preventatively to protect mental health of care staff exposed psychologically traumatic events during their COVID-19–related work. We have developed a brief behavioral intervention aims reduce number intrusive memories but only been face-to-face so far. After digitalizing materials, was digitally target users (health staff) first time....
Sleep problems and pain are common among the elderly have been shown to affect quality of life. The objectives were determine prevalence sleep compare two factors in relation age gender.
Hand hygiene (HH), a cornerstone in infection prevention and control, lacks quality emergency medical services (EMS). HH improvement includes both individual institutional aspects, but little is known about EMS providers' perception motivations related to quality. Therefore, we aimed investigate the assess potential factors self-reported compliance among cohort. A cross-sectional, self-administered questionnaire consisting of 24 items (developed from WHOs Perception Survey for Health-Care...
Abstract Background Older adults (age ≥ 65 years) represent a significant proportion of all patients who are not transported to hospital after assessment by ambulance clinicians (non-conveyed patients). This study aimed fill the knowledge gap in understanding prevalence older adult non-conveyed and investigate their characteristics risk factors for subsequent adverse events with those younger comparatively. Methods population-based retrospective cohort included availed service Region...
Registered nurses working on the frontline during COVID-19 pandemic encountered significant challenges, including exposure to critical incidents. Critical incidents refer sudden unexpected clinical events that surpass an individual's ability cope, leading considerable psychological distress, which could potentially result in development of post-traumatic stress disorder symptoms. Research has shown a high prevalence symptoms among healthcare workers, particularly those close contact with...
Abstract Background There is a notable variation in the percentage of non-conveyed patients within ambulance service. Discharging at scene includes risk adverse events, and both clinicians experience complexity non-conveyance. Therefore, this study aimed to describe factors influencing care encounter when service concludes with Method A qualitative design employing critical incident technique for data collection through individual interviews, analysis based on Fridlund et al. descriptions...
Abstract Background Clinical education in Emergency services (EMS) is unique due to its dynamic environment, brief patient encounters, and unpredictable cases. EMS provides valuable learning opportunities for nursing students, fostering person-centered care approaches a variation of clinical training learning. Formative feedback crucial develop knowledge skills. Multisource (MSF) offers comprehensive assessment by incorporating from various individuals, promoting self-reflection targeted MSF...
Abstract Background Because health professionals can end up being first responders to a mass casualty incident, they must train improve preparedness and increase the preconditions of victim outcomes. Training learning on how handle incident is traditionally based reading, lectures, training through computer-based scenarios, or sometimes live simulations. Professionals should practice in realistic environments narrow theory–practice gap, possibility repeating important for learning. Virtual...