- Date Palm Research Studies
- Medicinal Plants and Neuroprotection
- Aluminum toxicity and tolerance in plants and animals
- Insect Pest Control Strategies
- Pharmacological Effects of Medicinal Plants
- Heavy Metal Exposure and Toxicity
- Infrared Thermography in Medicine
- Genetic and Environmental Crop Studies
- Heavy Metals in Plants
- Animal Diversity and Health Studies
- African Botany and Ecology Studies
- Anesthesia and Neurotoxicity Research
- GABA and Rice Research
- Adipose Tissue and Metabolism
- Ethnobotanical and Medicinal Plants Studies
- Hibiscus Plant Research Studies
- Plant-derived Lignans Synthesis and Bioactivity
- Tryptophan and brain disorders
- Diverse Scientific Research Studies
- Evolution and Paleontology Studies
- Medicinal Plant Research
- Piperaceae Chemical and Biological Studies
- Animal testing and alternatives
- Medicinal Plant Extracts Effects
Ahmadu Bello University
2013-2024
Background and aim: Environmental health hazards posed by lead, a heavy metal contaminant, in water other media are rising. Different solvent-extract forms of the Phoenix dactylifera plant vast medicinal benefits. The neuroprotective effect chloroform fruit pulp extract P. (CFPD) was assessed on lead acetate-induced cerebellar cerebral toxicity Wistar rats. Materials methods: Twenty-four rats were divided into six groups: (A – F; n= 4): control (group A) administered distilled (2 ml/kg p.o);...
Tamarindus indica (TI) extract is known to possess important phytochemical composition. The study aimed assess the effects of ethyl acetate fraction TI leaves (EATI) on memory and learning, traced element brain sialic acid levels, hippocampal Nissl substance expression following prenatal (PN) AlCl3 exposure in Wistar rat pups. Pregnant rats were divided into 5 groups (n = 4); Group I received distilled water (negative control), II-V experimental treated with 200 mg/kg AlCl3. II (positive...
Diarrhea is one of the main causes morbidity and mortality in children under age 5 years. In view this problem, World Health Organization has encouraged studies for treatment prevention diarrhoeal diseases depending on traditional medicinal practices. Extracts <em>Phoenix dactylifera</em> (date palm) are widely used medicine various disorders. study, antidiarrhoeal activity aqueous fruit extract was investigated by castor oil- induced diarrhoea, enteropooling gastrointestinal motility Wistar...
Over time, the use of plant-derived agents in management various human health conditions has gained a lot attention. The study assessed hepatoprotective potential ethyl acetate fraction Tamarindus indica leaves (EFTI) during prenatal aluminum chloride exposure. Pregnant rats were divided into 5 groups (n = 4); Group I administered 2 ml kg−1 distilled water (negative control), II received only 200 mg (positive III and 400 EFTI, IV 800 V 300 Vit E (comparative control). On postnatal day 1,...
Context: Exposure to all forms of mercury has toxic effect on several biosystems. Disruption in structural, biochemical, and physiological renal integrity results nephrotoxicity. Citrus sinensis L (sweet orange) medicinal benefits for diverse ailments. Aim: This study evaluated the nephroprotective ethanol fruit peel extract C. (EPCS) against mercuric chloride (HgCl2)-triggered nephrotoxicity Wistar rats. Materials Methods: Twenty-five rats (150–180 g) were separated into five Groups (I-V, n...
Various parts of <em>Phoenix dactylifera</em> (date palm) are used in traditional medicine to treat various disorders such as fever, abdominal troubles, etc., different the world. A preliminary phytochemical screening aqueous fruit extract (AFPD) revealed presence alkaloids, tannins, saponins, flavonoids and carbohydrates. This study was designed investigate effects oral administration AFPD on histology liver kidney Wistar rats. Thirty-nine rats were divided into two groups-control (three...
Empirical assessments of the similarities and variations neurobiological structures in animals are basis comparative neuroanatomy. Animal models including small laboratory mammals indispensable tools for neuroanatomical research. The mammalian midbrain has been described with grey matter red nucleus (RN), substantia nigra (SN) involved important brain functions like regulation motor related activities. This study comparatively characterized features ventral (RN SN) three mammals: Wistar rat,...
Abstract Background Lead, a pervasive and toxic environmental pollutant, of particular concern is its impact as trigger for neurodegenerative diseases. Phoenix dactylifera (date palm), has garnered attention due to pharmacological properties: antioxidant anti‐inflammatory, attributed rich flavonoid content. This assessed the therapeutic potentials n‐ butanol fraction P. (BFPD) on behavioral histomorphology hippocampus lead acetate (PbA)‐induced neurotoxicity in Wistar rats. Method Forty‐two...
Abstract Background : Mercury is a highly toxic metal that causes severe damage to the body system of humans and animals establish contact with it. Date palm ( Phoenix dactylifera ) fruits have been documented possess several pharmacological abilities used in traditional medicine worldwide. The present study was aimed at assessing protective effects aqueous ethanolic fruit extracts L. on mercury-induced liver toxicity Wistar rats. Design; A total forty-five (45) rats male sex (80 – 125g)...
Abstract Introduction: Mercury is a highly toxic metal that exerts adverse effects on humans and animals. Date palm ( Phoenix dactylifera ) used in folk medicine to treat fever, inflammation, among others. The present study aimed evaluate the protective of aqueous ethanol extracts mercury-induced kidney damage Wistar rats. Design: 45 male rats (80–125g) were divided into nine groups (I-XI). Group 1 received 1mg/kg distilled water, group II mercury chloride (HgCl 2 at 5 mg/kg; III was...
Abstract Mercury is a highly toxic substance that poses serious threat to living organisms. This work evaluated the protective effects of n- butanol fraction Phoenix dactylifera Linn (BFPD) on mercury-induced kidney toxicity in Wistar rats. 25 rats were divided into 5 groups containing each. Group I was administered 2 ml/kg distilled water; group II mg/kg mercury chloride (HgCl ); III and IV received 500 1000 BFPD followed by HgCl respectively. V treated with 100 silymarin . All...
BACKGROUND AND AIM: Smokeless or “Spit” are products of tobacco without combustion pyrolysis at the time use and consumption smokeless continue to grow globally in form dipping, snuffing, chewing sniffing. The neurotoxic effect is well documented. Substantia nigra par reticularis, an important basal nuclei structure sets pattern for facilitation voluntary movements body. This study assessed methanol leaf extract Nicotiana tabacum (MLNT) on histomorphological studies substantia reticularis...
Objective: Myristica fragrans, a common kitchen spice, is reported to have psychoactive properties, producing hallucinations and fear. The action attributed the presence of myristicin. This study aimed assess effects ethanol seed extract fragrans (ESMF) on anxiety-like behaviour dopamine levels in rats. Materials Methods: Thirty-six male Wistar rats were divided into six groups each. Groups I (control, received 2 ml/kg distilled water); Group II (received tween 80 Oil); III, IV V ESMF (500...
Accumulation of aluminium chloride results in damage to different brain regions, and has been used model the hippocampus which can be associated with various neurodegenerative diseases such as Alzheimer’s Parkinson’s. The aim this study was assess protective effects eugenol on induced neurotoxicity adult Wistar rats. 30 rats were procured divided into six groups five animals each group, namely: EGH (300 mg/kg eugenol), EGL (150 EGH+AL 100 AlCl3), EGL+AL AL (100 AlCl3) CTRL (2 mL/kg distilled...