- Vascular Malformations and Hemangiomas
- Vascular Malformations Diagnosis and Treatment
- Vascular Tumors and Angiosarcomas
- Tumors and Oncological Cases
- Vascular Anomalies and Treatments
- Central Venous Catheters and Hemodialysis
- Ear and Head Tumors
- Dermatologic Treatments and Research
- Laser Applications in Dentistry and Medicine
- Teratomas and Epidermoid Cysts
- Trigeminal Neuralgia and Treatments
- Advanced MRI Techniques and Applications
- Hedgehog Signaling Pathway Studies
- Tuberous Sclerosis Complex Research
- Tissue Engineering and Regenerative Medicine
- Facial Rejuvenation and Surgery Techniques
- Pregnancy and preeclampsia studies
- Parvovirus B19 Infection Studies
- Congenital Anomalies and Fetal Surgery
- Cardiac tumors and thrombi
- Smart Parking Systems Research
- Histiocytic Disorders and Treatments
- Congenital Heart Disease Studies
- Reconstructive Surgery and Microvascular Techniques
- Facial Nerve Paralysis Treatment and Research
Shanghai Ninth People's Hospital
2015-2025
Shanghai Jiao Tong University
2016-2025
Chengdu University of Traditional Chinese Medicine
2024
Jinan Central Hospital
2023
International Peace Maternity & Child Health Hospital
2020
Health First
2017
Peking University First Hospital
2016
Peking University
2016
Kaposiform hemangioendothelioma (KHE) is a rare infiltrative vascular tumor that potentially life-threatening when presenting with Kasabach-Merritt phenomenon (KMP). KMP clinically characterized as severe thrombocytopenia and hypofibrinogenemia therefore associated high mortality rate. There no standard of cure for KHE currently. Potential medications, including corticosteroids, propranolol, chemotherapy drugs such sirolimus, are often used alleviating symptoms. Although some case reports...
The protocol for the treatment of infantile hemangioma with propranolol varies among different clinical centers.Six hundred seventy-nine patients who were 1 to 12 months old recruited in this prospective study receive treatment. response therapy was classified as 4 levels. results primarily evaluated using color Doppler ultrasound examinations before and after treatment.The excellent 176 (25.9%), good 492 (72.5%), stable 5 (0.7%), poor 6 (0.9%) patients. mean age at initiation 3.3 (range,...
Vascular malformations are congenital vascular developmental defects that usually grow slowly and persist throughout life. Venous (VMs) the most prevalent type of anomalies, representing roughly 70% all cases. VMs can cause significant pain, impaired mobility, disrupt organ function, in severe cases, become life-threatening. Intralesional sclerotherapy after tracheotomy is a safe effective treatment for extensive involving oropharyngeal areas head neck. For first time, we present...
Propranolol has been the first-line treatment for alarming hemangiomas. However, some hemangiomas are propranolol-resistant. The authors reported 1 propranolol-resistant hemangioma which was treated with intralesional bleomycin injections. Sixteen months after 3 injections, lesion still remained stable. Its potential mechanism clarified by ultrasonic monitoring. Intralesional injection can be considered an ideal option in treating
To evaluate the efficacy and safety of intralesional injection pingyangmycin for treatment microcystic lymphatic malformations (LMs) in tongue.Eighteen patients with tongue LMs were treated pingyangmycin. The concentration drug was 1 mg/mL an addition dexamethasone. Repeated injections performed at interval 3–4 weeks. results evaluated by clinical examinations Doppler ultrasonography scan. follow-up period 12 months to eight years after last mean time three years. All received 1–8 (mean, 3.0...
Few specific reports have addressed propranolol as a treatment for parotid hemangioma, and its mechanism remains unclear.Eighty-seven patients were recruited in this prospective study. Ten underwent detailed color Doppler examination. The depths, vessel densities, resistant indices of 10 lesions recorded analyzed before at 1 3 months after treatment.The overall responses "bad" 2 cases, "stable" 4 "good" 53 "excellent" 28 cases. Hemangioma regrowth was observed 11 cases (12.6%). parents 18...
Purpose: Despite many advances in the knowledge of vascular malformations, extracranial arteriovenous malformations (AVMs) remain an enigma and are usually misdiagnosed mismanaged due to their associated rare morbidity. This study aimed describe clinical course emphasize progressive nature AVMs through a retrospective 446 patients. Methods: Patients with cutaneous soft-tissue presenting our Vascular Anomalies Center between March 2011 2017 were reviewed. Medical records examined for disease...
Pain is a common symptom and the major complaint in patients with venous malformations of extremities, which may lead to joint dysfunction even walking disabilities. Therefore, this study aimed investigate determined independent risk factors for pain these patients. We retrospectively collected data 168 extremities from January 16, 2013 August 13, 2015. They were categorized into painful painless groups according scores. Associations between candidate using univariate multivariate analyses....
Background: Compared with singletons, a twin pregnancy is associated larger thyroid hormone demand and an increased stimulation of gestational function due to higher concentrations human chorionic gonadotropin. However, such effects have been sparsely quantified. The aim this study was evaluate test abnormalities in pregnancies during early late compared singletons. Methods: We included 1208 46,834 singleton tests available. Thyroid were defined using population-based reference ranges....
Objective To investigate the role of serum basic fibroblast growth factor (bFGF), estradiol (E2) and urine bFGF in differentiating infantile haemangiomas from vascular malformations. Method Between October 2007 January 2009, 97 patients with 25 malformations who had not been treated previously were included this prospective study. Forty-eight cleft lip and/or palate selected as controls. The age all subjects ranged 1 to 30 months. levels determined by enzyme-linked immunosorbent assay...
Propranolol has been the first-line treatment for problematic infantile hemangioma (IH) since 2008. The recurrence of IHs after stopping with propranolol was reported in several studies. Mechanisms underlying this phenomenon have not elucidated so far. Our study is first to show general pathology IH propranolol. It can provide help clinical IHs.
Adenoid cystic carcinoma (ACC) is a rare malignancy predominantly found in the salivary, lacrimal, upper gastrointestinal, and respiratory mucosal glands; adenoid of external auditory canal (EAC) particularly rare. Characterized by proclivity for recurrence metastasis, advanced often proves refractory to conventional chemotherapy. Novel therapeutic approaches, notably targeted therapies, are imperative enhance treatment response rates patients. Herein, we present case primary affecting right...