A5100458228- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Anorectal Disease Treatments and Outcomes
- Radiomics and Machine Learning in Medical Imaging
- Metastasis and carcinoma case studies
- Knee injuries and reconstruction techniques
- Macrophage Migration Inhibitory Factor
- Total Knee Arthroplasty Outcomes
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Endoplasmic Reticulum Stress and Disease
- Helicobacter pylori-related gastroenterology studies
- RNA Research and Splicing
- Cytokine Signaling Pathways and Interactions
- Gastrointestinal Tumor Research and Treatment
- Orthopedic Infections and Treatments
- Pancreatic function and diabetes
- Cancer Cells and Metastasis
- Cardiac, Anesthesia and Surgical Outcomes
- Liver Disease Diagnosis and Treatment
Shanghai Sixth People's Hospital
2025
First Affiliated Hospital of Dalian Medical University
2020-2024
Shanghai Cancer Institute
2024
Renji Hospital
2024
Shanghai Jiao Tong University
2024
Dalian Medical University
2020-2024
Weatherford College
2023
Nanjing Medical University
2014-2023
Jiangsu Province Hospital
2014-2023
University of Electronic Science and Technology of China
2023
The radioresistance of esophageal squamous cell carcinoma (ESCC) remains an obstacle for the effective radiotherapy ESCC. This study aimed to investigate radiosensitization ESCC by signal transducer and activator transcription 3 (STAT3) inhibitor stattic. ECA109, TE13, KYSE150 lines were exposed hypoxia treated with stattic or radiation, alone in combination. Cell proliferation, colony formation, apoptosis, double-stranded DNA breaks (DSBs) examined. In addition, ECA109 cells xenografted...
Objective Colorectal cancer (CRC) is a prevalent gastrointestinal tumor globally. Circular RNAs (circRNAs) have been identified as regulatory players in the pathogenesis of CRC. However, it unclear whether hsa_circ_0050102 (circPGPEP1) affects malignant progression and immune escape
To determine the diagnostic accuracy of preoperative T/N stage with magnetic resonance imaging (MRI) in lower and middle rectal cancer patients impacts on clinical decision-making.A total 211 were recruited from October 2015 to March 2017 this retrospective study. High-resolution MRI was performed within 2 weeks before surgery. Histopathologic results evaluated for postoperative assessed according histopathologic results. The accuracy, sensitivity, specificity, positive predictive value...
Abstract Background Laparoscopic tumor-specific mesorectal excision (TSME) preserving the left colic artery and superior rectal is still a technically challenging procedure. We conducted this study to demonstrate feasibility of procedure for upper cancer. Methods A total 184 patients with cancer were retrospectively analyzed in our center between April 2010 2017. These treated either laparoscopic TSME ( n = 46) or (TME) 138). In group, colonic preserved while they not TME group. Results The...
Background: After pre-operative concurrent long course chemoradiotherapy (CRT), pathologic complete response (pCR) has been reported with better oncologic outcomes in many articles, whether a moderate (TRG1) can translate into good clinical outcome remains uncertain. Methods: A total of 132 locally advanced rectal cancer patients neoadjuvant followed by radical surgery were recruited. Their clinicopathologic characteristics and records retrospectively reviewed. The association between...
Abstract Background To investigate the short-term and long-term outcomes of preserving celiac branch vagus nerve during laparoscopic distal gastrectomy. Methods A total 149 patients with prospective diagnosis gastric cancer who underwent laparoscopic-assisted gastrectomy (LADG) combined Billroth-II anastomosis D2 lymph node dissection between 2017 2018 were retrospectively analyzed. The divided into preserved LADG group (P-LADG, n = 56) resected (R-LADG, 93) according to whether was...
Capecitabine-based neoadjuvant chemoradiotherapy (nCRT) is the standard treatment for locally advanced rectal cancer. The objective of this study to analyze overall survival (OS), disease-free (DFS) and prognostic factors patients with stage II III cancer treated nCRT in our institution. Between March 2014 June 2020, 121 were retrospectively reviewed analyzed. All enrolled capecitabine-based (pelvic radiotherapy: 45-50.4 Gy, 1.8 Gy/d plus concomitant chemotherapy), total mesorectal excision...
Background: After pre-operative concurrent long course chemoradiotherapy (CRT), pathologic complete response (pCR) has been reported with better oncologic outcomes in many articles, whether a moderate (TRG1) can translate into good clinical outcome remains uncertain. Methods: A total of 132 locally advanced rectal cancer patients neoadjuvant followed by radical surgery were recruited. Their clinicopathologic characteristics and records retrospectively reviewed. The association between...
Abstract Background Laparoscopic TSME preserving the left colic artery and superior rectal is still a technically challenging procedure. We conducted this study to demonstrate feasibility of procedure for upper cancer. Methods A total 184 patients with cancer were retrospectively analyzed in our center between April 2010 2017. These treated either laparoscopic (n=46) or TME (n=138). In group, colonic preserved while they not group. Results The operation time group was longer than that...
Abstract Background: The management of rectal carcinoma has substantially evolved over the past two decades, so as AJCC staging and NCCN guidelines. inherent relationships pathologic factors warrant further study. present study aimed to assess associations clinical pathological in cancer patients undergoing radical surgery. Methods : From October 2015 February 2019, all treated with surgery without neoadjuvant therapy were identified. analysis was performed data obtained from prospectively...
Abstract Background This study aimed to assess the efficacy, feasibility, and safety of robot-assisted pylorus- vagus nerve-preserving gastroplasty (RA[PPG]), using da Vinci Surgical System, compared with those laparoscopy-assisted PPG (LAPPG). Methods Clinical follow-up data patients who underwent were retrospectively analyzed, which included 14 RAPPG 21 LAPPG cases. The histological data, surgical results, postoperative recovery, complication rates between two groups; experience was also...
Abstract Purpose Neoadjuvant chemoradiotherapy (nCRT) has been recommended as a standard treatment for locally advanced rectal cancer. In our study, we retrospectively analyzed the oncological outcomes of patients with stage II-III cancer who were treated in department. Patients and Methods During March 2014 to June 2020, total 139 reviewed, whom 121 analyzable. All enrolled II III nCRT capecitabine-based regimen, mesorectal excision surgery, an adjuvant chemotherapy regimen. We examined...