A5070832733- Catalytic Processes in Materials Science
- Cerebral Palsy and Movement Disorders
- Infant Development and Preterm Care
- Catalysis and Oxidation Reactions
- Synthesis and properties of polymers
- Semiconductor materials and devices
- Botulinum Toxin and Related Neurological Disorders
- Stroke Rehabilitation and Recovery
- Metal and Thin Film Mechanics
- Healthcare professionals’ stress and burnout
- Parvovirus B19 Infection Studies
- COVID-19 and Mental Health
- Neurological Complications and Syndromes
- Viral Infections and Immunology Research
- Innovations in Medical Education
- Neonatal and fetal brain pathology
- Catalysts for Methane Reforming
- Diamond and Carbon-based Materials Research
- Prosthetics and Rehabilitation Robotics
- Moyamoya disease diagnosis and treatment
- Hospital Admissions and Outcomes
- COVID-19 and healthcare impacts
- Craniofacial Disorders and Treatments
- Ga2O3 and related materials
- Thin-Film Transistor Technologies
National University of Singapore
2000-2025
National University Health System
2016-2025
National University Hospital
2008-2025
Khoo Teck Puat Hospital
2015-2022
Imperial College Healthcare NHS Trust
2016
Imperial College London
2016
OBJECTIVES: Chronic diarrhea caused by primary bile acid (PBAD) is a common condition. We have previously shown PBAD associated with low fasting serum levels of the ileal hormone, fibroblast growth factor 19 (FGF19). FGF19 negative regulator hepatic synthesis and stimulated farnesoid X receptor agonists, which produce symptomatic improvement in PBAD. aimed to assess possible causes for patients METHODS: Patients PBAD, defined reduced 75Se-labelled homocholic taurine (SeHCAT) retention,...
Children affected by hand impairment due to cerebral palsy or stroke experience serious difficulties when performing activities of daily life (ADL), which reduces their quality and development. Wearable robots such as exoskeletons have been proposed support people with in therapy well tasks. While numerous actuated wearable developed, few designs both fingers wrist function, despite being mutually relevant for reach-to-grasp A recent feasibility study investigating the use PEXO, a...
INTRODUCTION Coronavirus disease 2019 (COVID-19) restrictions reduced real-world experience-based learning, which is crucial for developing clinical reasoning, highlighting the need alternative training methods.[1] To fill this gap, we explored virtual simulation-based education (SBE), has been shown to be an effective teaching tool.[2] We identified Full Code©, a suitable proprietary web-based simulation program that trains analyses participant performance and provides direct feedback...
Importance Extended work hours and night shifts are essential in health care, but negatively affect physician sleep, well-being, patient care. Alternative schedules with shorter and/or reduced irregularity might mitigate these issues. Objective To compare cognition between interns working irregular, extended (call schedule), those a more regular schedule restricted (float schedule). Design, Setting, Participants In this observational longitudinal cohort study, Singapore-based teaching...
This paper presents the results of a preliminary study with one cerebral palsy child using ReHaptic Handle, novel robotic device for pediatric rehabilitation upper limb function. The has two degrees-of-freedom to train pinching, forearm supination/pronation and wrist flexion/extension movements. Interactive computer games have been implemented increase subjects' participation engagement, thus promoting motor recovery. Pinching, index finger thumb, as well were trained or three times week 15...
INTRODUCTION Enterovirus infections in childhood can be associated with significant neurological morbidity.This study aimed to describe the prevalence and range of manifestations, determine clinical characteristics assess differences outcomes for Singaporean children diagnosed enterovirus infections. METHODSIn this single-centre, case-control study, data was collected retrospectively from patients admitted National University Hospital, Singapore, August 2007 October 2011 infection, based on...
Introduction: With better medical care, patients with Duchenne muscular dystrophy (DMD) now live longer but face more complex and social needs. This study described the perceptions of DMD their families disease-specific palliative care services in Singapore. Materials Methods: A multicentre, crosssectional involving was carried out. Structured questionnaires were administered to them collect data on understanding health accessed desired by quality life. Results: total 30 pairs caregivers...
The growth trends of Singapore children spanning 5 decades are reviewed, based on 8 anthropometric studies from 1957 till 2002. heights pre-school and school age appear to have optimised according their genetic potential, but the weights body mass indices still be increasing 6 18 years for both sexes, probably as a consequence affluence. This trend is reflected in obesity prevalence over past 30 years, concomitant increased morbidity associated with metabolic syndrome, necessitates further...
Introduction: Children from low-income (LI) families often suffer poor health, with sub-optimal health practices. This cross-sectional study examined the differences in habits and health-related quality of life (HRQoL) LI preschool children compared to non-low-income peers (PPG). Method: Using data social-health Circle Care-Health Development Screening Programme (CoC-HDSP) Singapore, 118 304 PPG aged 18 months 6 years old their were recruited 13 government-funded preschools. Health practices...
Carbon nitride (CN) thin films were deposited on Si(111) substrates by reactive radio-frequency magnetron sputtering. The effect of thermal annealing the structural properties has been studied Fourier-transform infrared spectroscopy (FTIR) and x-ray photoelectron (XPS). Both FTIR XPS results show that amount CN phase decreases upon it is eliminated at C. Increasing temperature leads to formation a more prominent peak corresponding tetrahedral bonds in absorption spectra. N 1s peaks indicate...
Purpose/Aim: Acute movement disorder is an uncommon presenting symptom in patients with diabetes mellitus. We report a 20-year-old lady poorly controlled type 1 diabetes, who presented acute hemichorea and was found to have two rare diabetes-related central nervous complications of diabetic striatopathy severe moyamoya disease (MMD).Materials methods: She treated aggressive glycemic control; clonazepam tetrabenazine as well aspirin stroke prophylaxis for her MMD resolution chorea 3 months...
Bimetallic Pt–Co and monometallic Pt Co catalysts in as-prepared reduced states were characterized by X-ray diffraction, temperature-programmed reduction, XPS Farier transform infrared spectroscopy (FTIR). Temperature-programmed reduction results showed that the addition of platinum lowered temperature cobalt oxides simultaneously increased amount surface phase. The metallic bimetallic was found to be highly dispersed supports. In situ FTIR study CO adsorption on confirmed there either...
Introduction: The night float (NF) system has been instituted in some hospitals Singapore to improve the working hours and wellbeing of junior doctors. There have concerns compromised learning patient safety with NF. objective this study is compare clinical competency outcomes, based on existing assessment framework, between post-graduate year 1 (PGY1) doctors NF versus traditional call (TC) systems. secondary aim was explore outcomes these groups PGY1s. Methods: Data formal assessments...
Abstract: Aromatic L-amino acid decarboxylase (AADC) deficiency is an autosomal recessive neurotransmitter defect that results in a combined central of monoamines, namely catecholamines and serotonin. To date, less than 100 patients have been described with AADC deficiency, most severe neurological phenotype. This review article illustrates the pathophysiology, diagnostic methods, therapeutic strategies for deficiency. Two our institution extremely mild phenotypes their robust response to...
Abstract Multiple energy Al + and C ions were implanted into 6H‐SiC at room temperature (25°C) elevated (600°C), respectively, followed by 1550°C annealing for 30 min. Fourier transform infrared spectroscopy was used to evaluate the optical properties in mid‐infrared range. An effective medium model, taking account presence of an implantation‐induced amorphous phase, developed establish relationship between changes modification structure. Complete amorphization layer evidenced implantation...