A5040612249- HIV/AIDS Research and Interventions
- Reproductive Biology and Fertility
- HIV, Drug Use, Sexual Risk
- Reproductive System and Pregnancy
- Ovarian function and disorders
- Adolescent Sexual and Reproductive Health
- Liver Disease Diagnosis and Treatment
- Circular RNAs in diseases
- Psoriasis: Treatment and Pathogenesis
- Endometriosis Research and Treatment
- Gout, Hyperuricemia, Uric Acid
- Apelin-related biomedical research
- HIV-related health complications and treatments
- HIV Research and Treatment
- Hypothalamic control of reproductive hormones
- Nuclear Receptors and Signaling
- Mesenchymal stem cell research
- Hepatocellular Carcinoma Treatment and Prognosis
- Ovarian cancer diagnosis and treatment
- Gut microbiota and health
- Genetic Associations and Epidemiology
- Dermatology and Skin Diseases
- Tryptophan and brain disorders
- Heme Oxygenase-1 and Carbon Monoxide
- Adenosine and Purinergic Signaling
Binzhou University
2016-2025
Binzhou Medical University
2017-2025
Guangzhou University of Chinese Medicine
2023-2025
Ningbo University
2024
Northwest University
2023
Xinjiang Medical University
2023
Taihe Hospital
2023
Hubei University
2023
Nanjing University of Chinese Medicine
2021
Guangxi Medical University
2020
Abstract Background This study was performed to determine the effects of human placenta mesenchymal stem cell (hPMSC) transplantation on granulosa apoptosis and anti-Müllerian hormone (AMH) follicle-stimulating receptor (FSHR) expression in autoimmune drug-induced premature ovarian failure (POF) mice. The aim this research is investigate mechanisms hPMSCs reserve capacity. Methods POF mice model established by injection zona pellucida 3 peptide (pZP3). hPMSC conducted intravenous into...
Abstract Objective The basic pathological changes of primary ovarian insufficiency (POI) include tissue fibrosis and follicular development disorders. human umbilical cord mesenchymal stem cell (hUMSC) transplantation has been shown an effective method to improve the function in POI rat model; however, exact mechanisms are still unclear. purpose this study is investigate whether recovery rats related inhibition following hUMSC transplantation. Furthermore, transforming growth factor-β 1...
Abstract Background Psoriasis is an immune‐mediated chronic inflammatory skin disease. Great progress has been made in the pathogenesis of psoriasis recent years, but there no bibliometric study on psoriasis. The purpose this was to use bibliometrics method analyze research overview and hot spots 10 so as further understand development trend frontier field. Methods core literatures were searched Web Science database, analyzed by VOSviewer, CiteSpace, Bibliometrix terms annual publication...
Background: Psoriasis, a chronic skin condition characterized by systemic inflammation and altered gut microbiota, has been target of Traditional Chinese Medicine (TCM) for centuries. Shenling Baizhu Powder (SLBZP), TCM formulation, holds promise treating inflammatory diseases, but its specific role in psoriasis impact on microbiota is not fully understood. Objective: This study aims to elucidate the mechanism SLBZP psoriasis, integrating component analysis, network pharmacology,...
Human placenta-derived mesenchymal stem cell (hPMSC) transplantation has been demonstrated to be an effective way of recovering ovarian function in mice with autoimmune induced premature failure (POF). But the exact mechanism remains unclear. The goal present study is investigate role immune factors (T-helper 17 (Th17), cytotoxic T (Tc17) and regulatory (Treg) cells) recovery whether phosphatidylinositol 3-kinase (PI3K)/Akt signal pathway involved regulation.The inhibitor PI3K/Akt was...
To explore the mechanism of human umbilical cord-derived mesenchymal stem cell (hUMSC) transplantation to improve ovarian function and endometrial receptivity in autoimmune premature failure (POF) mice. The POF model was established mice treated with zona pellucida 3 polypeptide fragment (zona 3, ZP3). hUMSCs were transplanted into through tail vein injection. Following transplantation, serum hormone levels follicle stimulating (FSH), estrogen (E2), progesterone (P), γ-interferon (IFN-γ),...
Previous studies have shown that the ovarian failure in autoimmune-induced premature (POF) mice could be improved by transplantation of human placenta-derived mesenchymal stem cells (hPMSCs); however, protective mechanism hPMSCs on dysfunction remains unclear. Ovarian is closely related to apoptosis granulosa (GCs). To determine effects GCs apoptosis, an autoimmune POF model was established with zona pellucida glycoprotein 3 (ZP3) peptide. It reported inositol-requiring enzyme 1α (IRE1α) and...
Men who have sex with men (MSM) in China hold a low-risk perception of acquiring HIV. This has resulted an inadequate HIV testing rate.This study aims to investigate whether administering risk self-assessments tailored feedback on gay geosocial networking (GSN) app could improve rates and reduce sexual behaviors Chinese MSM.We recruited MSM from Beijing, China, used the GSN platform Blued October 2017 this 12-month double-blinded randomized controlled trial. From September 2018, eligible...
Abstract Background Human umbilical cord mesenchymal stem cells (hUCMSCs, retrospectively registered) have a lot of promise for treating theca interstitial cells(TICs) dysfunction in premature ovarian insufficiency (POI). The mechanisms, however, are still unknown. Methods To examine the therapeutic and find cause, we used both vivo cisplatin-induced POI rat model vitro TICs model. HUCMSCs were injected into tail veins rats an investigation. Then, using ELISA, HE staining, TUNEL apoptosis...
Addressing the burden of human immunodeficiency virus (HIV) infection among men who have sex with (MSM) has become a major priority. Over years, post-exposure prophylaxis (PEP) proven efficacy in preventing HIV transmission. However, widespread underutilization PEP undermines its protective potential. To address this issue, we developed an innovative, gamified mini-app embedded WeChat, known as O2O-PEP (online-to-offline collaborative model for postexposure prophylaxis), that targets uptake....
Although increasing lines of evidence showed associations between serum uric acid (UA) levels and schizophrenia, the causality direction remain uncertain. Thus, we aimed to assess whether relationships UA schizophrenia are causal determine association.Two-sample bidirectional Mendelian randomization (MR) analyses various sensitivity were performed utilizing summary data from genome-wide association studies within Global Urate Genetics Consortium Psychiatric Genomics Consortium. Secondary MR...
Abstract Photosensitive supercapacitors incorporate light‐sensitive materials on capacitive electrodes, enabling solar energy conversion and storage in one device. In this study, heterogeneous structures of rod‐shaped ZnO decorated with Ce 2 S 3 nanoparticles nickel foam (ZnO@Ce /NF) are synthesized using a two‐step hydrothermal method as photosensitive supercapacitor electrodes for capacitance enhancement under visible light. The formation ZnO@Ce is confirmed various structural...
To assess the challenges to and provide a response strategy for development of nursing make suggestions promoting discipline, platform, talent teams based on current best available evidence.We searched CNKI(China National Knowledge Infrastructure), VIP information(Chinese Scientific Journals database), CBM(Chinese Biomedical Literature Web sites World Health Organization, International Council Nurses, Bank, Ministry Education China, relevant schools in China. Data analyses were performed...
Objectives To assess the quality of currently available clinical practice guidelines (CPGs) for hepatocellular carcinoma, and provide a reference clinicians in selecting best protocols. Methods The databases PubMed, MEDLINE, Web Science, Chinese Biomedical Literature database (CBM), China National Knowledge Infrastructure (CNKI), WanFang, relevant CPGs websites were systematically searched through March 2014. was appraised using Appraisal Guidelines Research & Evaluation (AGREE) II...