A5058645849- Childhood Cancer Survivors' Quality of Life
- Neutropenia and Cancer Infections
- Sarcoidosis and Beryllium Toxicity Research
- Lymphoma Diagnosis and Treatment
- Global Cancer Incidence and Screening
- Viral-associated cancers and disorders
- Breast Cancer Treatment Studies
- Classical Philosophy and Thought
- Hemoglobinopathies and Related Disorders
- Radiomics and Machine Learning in Medical Imaging
- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Renal and related cancers
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Parvovirus B19 Infection Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Acute Myeloid Leukemia Research
- Education and Critical Thinking Development
- Oropharyngeal Anatomy and Pathologies
- Peptidase Inhibition and Analysis
- Mast cells and histamine
- Lymphadenopathy Diagnosis and Analysis
- Radiology practices and education
- AI in cancer detection
Respiratory and Meningeal Pathogens Research Unit
2021
Chris Hani Baragwanath Hospital
2003-2021
University of the Witwatersrand
2003-2021
Johns Hopkins Hospital
2003
South African Institute for Medical Research
2003
Johannesburg Hospital
2003
Northern Hospital
1976-1982
Middlesex Hospital
1968-1970
North Middlesex Hospital
1967
In a series of 34 patients with sarcoidosis affecting the upper respiratory tract and nose, 26 had lupus pernio (LP) 17 (SURT). nine these features coexisted. A patient presenting SURT carried 50% risk developing LP although one feature could be present without other. Both were disorders women child-bearing years life. SURT, like LP, was an indicator chronic fibrotic sarcoidosis, insidiously progressing indolently over years. It complicated by ulceration, septal perforation, LP. Three nasal...
A series of eight hundred and eighteen patients with histologically-confirmed multisystem sarcoidosis was analysed; within this were 53 (6 per cent) the upper respiratory tract (SURT). Two-thirds presented predominantly symptoms when systemic disorder minimal or unrecognized. Women affected twice as often men. SURT is commonly associated lupus pernio other manifestations chronic fibrotic sarcoidosis, it follows same indolent course. When granulomas are found on biopsy tract, there should be...
Two thirds of children with cancer never reach a specialist centre for treatment in South Africa. The majority those who present have advanced disease. A campaign was undertaken to educate the public and primary health workers on Saint Siluan early warning signs children. There statistically significant increase number new patients referred 6 years following (P = 0.001), but did not succeed achieving referral at earlier stages This list appears be useful promoting awareness cancer.
PURPOSE Response assessment of classical Hodgkin lymphoma (cHL) with positron emission tomography-computerized tomography (PET-CT) is standard care in well-resourced settings but unavailable most African countries. We aimed to investigate correlations between changes PET-CT findings at interim analysis blood test results pediatric patients cHL 17 South centers. METHODS Changes ferritin, lactate dehydrogenase (LDH), erythrocyte sedimentation rate (ESR), albumin, total white cell count (TWC),...
The progress of a female child with African type Fanconi anemia that evolves in time into paroxysmal nocturnal hemoglobinuria is described. Modern diagnostic methods are used to confirm this process. A discussion possible mechanisms ensues.
The features of lipoid proteinosis which are particular interest to the laryngologist reviewed. It is suggested that raised serum alkaline phosphatase case described could be result increased lipo-glycoprotein synthesis and one long term consequence this endocranial calcification. latter has been clearly localised. also in a family occurs member, may perhaps taken as an indication latent otherwise clinically normal member.
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<strong>Background</strong>: Neonatal tumours, occurring within 28 days of life, are associated with a favourable outcome in high-income countries. Limited data available on neonatal tumours low- and middle-income countries.<br /><strong>Aim</strong>: We aimed to create awareness country, by identifying the most common diagnosed determine whether there was delay presentation or diagnosis at Paediatric Oncology unit, identify possible areas improvement increase...
Background: Infections in children treated for cancer contribute to morbidity and mortality. There is a paucity of studies on the incidence, etiology, risk factors outcome bacterial infections African cancer. The aim study was delineate epidemiology infectious mortality with Methods: enrolled 1–19 years old infections. Children were investigated infection as part standard care. Results: One hundred sixty-nine enrolled, 82 hematologic malignancies 87 solid tumors 10.7% HIV infected. incidence...
Background: Children with cancer are immunocompromised increased susceptibility to infections. We evaluated the burden of tuberculosis in children cancer. Methods: were enrolled and screened for Mycobacterium infection using tuberculin skin test enzyme-linked immune absorbent spot (T-SPOT.TB; Oxford Immunotec Ltd, Oxford, United Kingdom). physician-suspected investigated M. microscopy culture on sputum or gastric washings. Results: 169 children; 10.7% living HIV. The was positive 2.9%...
Developing countries with an uncontrolled AIDS epidemic have new challenges to meet in ITP. Secondary ITP, HIV related, becomes increasing problem, which has many aspects that need addressing, including medical, effective counseling, psychosocial and unresolved management issues. Assistance developing treatment guidelines is urgently needed.
Journal Article Book Reviews Get access Gabriel Marcel : Philosophe et Dramaturge. By Edgard Sottiaux. (Louvain Nauwelaerts. 1956. Pp. 219. Price Fr. b. 99). D. M. Mackinnon Search for other works by this author on: Oxford Academic Google Scholar The Philosophical Quarterly, Volume 9, Issue 35, April 1959, Pages 191–192, https://doi.org/10.2307/2216445 Published: 01 1959
Juvenile myelomonocytic leukaemia (JMML) is an aggressive clonal haematopoietic disorder that presents in early childhood. It classified by the World Health Organization (WHO) as overlap myeloproliferative or myelodysplastic disorder. The pathogenesis of JMML has been well-explained at molecular level using clear diagnostic criteria. There limited literature on context HIV infection. only curative modality for majority patients with allogeneic stem cell transplant (HSCT). role other...
Abstract Background Infectious complications in children treated for cancer contribute to their morbidity and mortality. There is a paucity of studies on the incidence, microbiological etiology, risk factors, outcome serious bacterial infections African cancer. Aim The aim study was delineate epidemiology infectious mortality South with Methods This prospective, single-center, longitudinal-cohort enrolled one-19 years old hospitalized treatment at Paediatric Oncology Unit, Chris Hani...