A5004953583- Bone and Dental Protein Studies
- dental development and anomalies
- Mesenchymal stem cell research
- Periodontal Regeneration and Treatments
- Bone Tissue Engineering Materials
- Endodontics and Root Canal Treatments
- Immune Response and Inflammation
- NF-κB Signaling Pathways
- Oral and Maxillofacial Pathology
- Adipokines, Inflammation, and Metabolic Diseases
- Graphene and Nanomaterials Applications
- Dental Radiography and Imaging
- Meat and Animal Product Quality
- Adipose Tissue and Metabolism
- Atherosclerosis and Cardiovascular Diseases
- Inflammatory Biomarkers in Disease Prognosis
- Bone Metabolism and Diseases
- Cancer-related molecular mechanisms research
- Protease and Inhibitor Mechanisms
- Occupational health in dentistry
- Metabolism, Diabetes, and Cancer
- Bioactive natural compounds
Nanjing Medical University
2010-2020
Hengyang Academy of Agricultural Sciences
2020
Wuhan University of Science and Technology
2018
University of Alberta
2016
Abstract Long noncoding RNAs (lncRNAs) exert significant roles at transcriptional and post-transcriptional levels. Stem cells from apical papilla (SCAPs) differentiate into dentin/bone-like tissues under certain conditions. So far, whether lncRNA-H19 can affect the proliferative behaviors osteo/odontogenesis of SCAPs, as well its specific mechanism remain to be elucidated. Here, SCAPs were isolated transfected with lentiviruses or packaging vectors. Our results showed that had no effect on...
Background information. Immature dental papilla stem cells and mature pulp are capable of performing the dentinogenesis under suitable circumstances. However, a dentinogenic comparison between immature root remains unknown. Results. iRPSCs (immature cells) at root-forming stage mRPSCs (mature root-completed were isolated from 16-day-old 8-week-old rat first molar roots, respectively. Growth kinetics flow cytometry results showed that presented more active proliferation properties than...
Abstract Objectives Stem cells from the dental apical papilla ( SCAP s) can be induced to differentiate along both osteoblast and odontoblast lineages. However, little knowledge is available concerning their differentiation efficiency in osteogenic media containing additional KH 2 PO 4 . Materials methods were isolated papillae of immature third molars treated with two kinds mineralization‐inducing media, MM 1 2, differing concentration. Proliferation osteo/odontogenic capacity 1/ 2‐treated...
BACKGROUND:Lysophosphatidic acid (LPA) is an active compound of oxidized low-density lipoprotein that serves as endogenous TLR4 ligand. Ligand activation activates nuclear factor-kappaB (NF-κB) and the transcription NF-κB-regulated inflammatory cytokines, which are involved in development atherosclerosis. MMP9 a member MMP family can affect plaque stability. However, mechanism responsible for effect LPA on expression has not been fully elucidated. In present study we examined activity THP-1...
Abstract BACKGROUND The present study aimed to evaluate the correlations among muscle concentrations of three glycometabolic‐related hormones (insulin, epinephrine and glucagon), glycolysis meat quality in representative muscles either glycolytic or oxidative types. Moreover, relative gene expression was measured. One Western crossbreed DLY (Duroc × (Landrace Yorkshire)), one with half‐Chinese native‐pig origin DL LiangShan ) pure Chinese native pig TP (Tibetan pig) were used study. RESULTS...
Background. Oral and maxillofacial bone loss is highly prevalent among populations, nowadays, increased attention has been focused on dentin derivatives serving as desirable graft materials for regeneration. In this study, dentin-derived inorganic mineral (DIM) was fabricated with a high-temperature calcination technique the effects of DIM osteogenic differentiation marrow-derived mesenchymal stem cells (BMMSCs) formation were elucidated. Methods. The BMMSC proliferation apoptosis capacity...
Abstract Oxidized low-density lipoprotein (ox-LDL) was known to induce endothelial cell injury the progression of atherosclerosis (AS). Sophocarpine (SPC), a compound sophora alkaloids isolated from plant Sophora alopecuroides, has been shown exhibit various pharmacological activities. This study designed investigate protective effect SPC on ox-LDL-induced cells and explored its underlying mechanism. Our results show that pre-incubation ameliorated ox-LDL-mediated HAECs cytotoxicity, DNA...
Abstract Background Oral and maxillofacial bone loss is highly prevalent among populations nowadays increased attention has been focused on dentin derivatives as desirable graft materials for regeneration. In this study, dentin-derived inorganic minerals (DIM) were fabricated with a high-temperature calcination technique the effects of DIM osteogenic differentiation marrow-derived mesenchymal stem cells (BMMSCs) formation elucidated. Methods The BMMSCs proliferation, apoptosis capacity...