- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Cardiovascular Health and Disease Prevention
- Cardiovascular Disease and Adiposity
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiovascular Effects of Exercise
- Metabolism, Diabetes, and Cancer
- Cardiomyopathy and Myosin Studies
- Nitric Oxide and Endothelin Effects
- Cancer, Hypoxia, and Metabolism
- Elasticity and Material Modeling
- Cerebrovascular and Carotid Artery Diseases
- Gastric Cancer Management and Outcomes
- TGF-β signaling in diseases
- Estrogen and related hormone effects
- Biomarkers in Disease Mechanisms
- Glutathione Transferases and Polymorphisms
- Aortic Thrombus and Embolism
- Bone health and osteoporosis research
- Cancer, Lipids, and Metabolism
- Cancer-related Molecular Pathways
- Growth Hormone and Insulin-like Growth Factors
- Healthcare Systems and Public Health
Changzhou No.2 People's Hospital
2017-2023
Nanjing Medical University
2019-2023
Huaian First People’s Hospital
2023
North China University of Science and Technology
2017
Second Affiliated Hospital of Nanjing Medical University
2013
Loma Linda University
1996
Jerry L. Pettis Memorial VA Medical Center
1996
Impairment of left ventricular (LV) longitudinal function has an important role in hypertrophic cardiomyopathy (HCM). This research investigated association between the strain different myocardial layers, rotation and LV systolic HCM patients. The was performed on 36 patients healthy subjects. peak subendocardial, midmyocardial, subepicardial layers measured using 2-dimensional speckle tracking echocardiography (2D–STE). apical long-axis 4- 2- chamber views were acquired via 2D Doppler...
Abstract Background To detect the right atrial (RA) functions in hypertrophic cardiomyopathy (HCM) patients by using volume-derived values and two-dimensional strain. Methods Thirty-two HCM 34 age gender matched normal controls were enrolled for this study. RA measured 2D ultrasonic images. strain (S-reservoir, S-conduit, S-booster pump) rate (SR-reservoir, SR-conduit, SR-booster pump), representing reservoir, conduit booster pump functions, respectively, EchoPAC. Results Total emptying...
Abstract Background This study investigated the value of layer-specific strain analysis by two-dimensional speckle tracking echocardiography (2D-STE) for evaluating left ventricular (LV) systolic function and synchrony in maintenance hemodialysis (MHD) patients. Methods A total 34 MHD patients 35 healthy controls were enrolled this study. Dynamic images collected at LV apical long-axis, four- two- chamber, short-axis views basal, middle, segments. The (LST) technique was used to analyze...
Epicardial adipose tissue is an emerging cardiovascular risk factor. The aim of this study was to evaluate right ventricular function and investigate its association with EAT in T2DM patients.154 patients were divided into two groups according thickness: <5 mm ≥5 mm. Seventy non-T2DM enrolled as control group. RV evaluated using both conventional echocardiography well two-dimensional speckle tracking echocardiography. thickness measured the echo-free space between free wall ventricle...
To evaluate the left ventricular (LV) longitudinal function changes in rabbits after acute occlusion of anterior descending artery (LAD) by two-dimensional speckle tracking imaging (2D–STI). Forty-eight New Zealand white underwent echocardiography examination. EchoPAC was used to measure LV peak systolic strain (LS) endocardium, middle myocardium, and epicardium, rate (LSr), segmental global rotation (LR) degrees. Ligated LAD repeated all measurements 10 min. Peak LS LSr were significantly...
Abstract Background Hypertension is the most common chronic disease and important risk factor for cardiovascular cerebrovascular diseases. Atheroma arteriosclerosis plays a key role in occurrence development of hypertension. The purpose this study was to evaluate elasticity ascending aorta wall patients with essential hypertension (EH) using M‐mode echocardiography. Materials Methods We prospectively enrolled 54 EH 51 healthy subjects (HS). They all underwent transthoracic echocardiography...
Epicardial adipose tissue (EAT) is an emerging cardiovascular risk factor located between the myocardium and visceral pericardium. In order to investigate association EAT ascending aorta elasticity in patients with type 2 diabetes mellitus (T2DM), we prospectively enrolled a total of 135 T2DM 63 age- gender-matched non-T2DM controls this study. They all underwent transthoracic echocardiography measure thickness inner diameters which were used calculate elastic parameters: compliance (C),...
Both essential hypertension (EH) and type 2 diabetes mellitus (T2DM) can impair the elasticity of ascending aorta. We prospectively enrolled 42 patients with T2DM, 44 EH, 45 T2DM EH (T2DM + EH), 41 healthy subjects (HS). They all underwent transthoracic echocardiography to measure aorta inner diameters a brachial blood pressure measurement calculate aortic elastic parameters (ie, compliance, distensibility, strain, stiffness index, Peterson modulus). found that there were no significant...
Objective:To investigate the role of metformin in inducing apoptosis papillary thyroid carcinoma BCPAP cells. Method:Using MTT methods to detect effects on cell proliferation different concentrations (0 mmol/L, 1 5 10 20 mmol/L) and time course h, 4 8 16 24 48 h). The experiment was divided into four groups: Con, Met, Met+Sal Met+DM, flow cytometry rate BCPAP. Then protein expressions CHOP, GRP78 Caspase-12 groups by Western blot. Result:Compared with experimental control group, percentage...
Objective:To establish an subcutaneous xenotransplanted tumor model of papillary thyroid carcinoma (PTC) and investigate the role metformin in apoptosis PTC.Method:Model rats were randomly divided into four groups: control group, Met group Met+DM group. The volumes recorded each week. Flow cytometry was used to detect rate tumor. Immunohistochemistry CyclinD1 cellular proliferative activity index PCNA Ki-67.Result:Compared group,there a significant decrease volume antitumor effect groups....
Abstract Background: Type 2 diabetes mellitus (T2DM) is associated with high cardiovascular risk. Preclinical left ventricular (LV) dysfunction and subclinical arterial stiffness have been documented in patients T2DM. The aims of this study were to investigate whether there was any differences LV function ascending aorta elasticity between T2DM controlled [defined as glycosylated hemoglobin (HbA 1c ) <6.5%] uncontrolled ≥6.5%) blood glucose. Methods: We studied 86 preserved ejection...
Objective To assess the left ventricular function and longitudinal rotation in rabbits after acute occlusion of anterior descending artery by two-dimensional speckle tracking imaging (2D-STI).Methods 48 New Zealand white underwent conventional echocardiography examination,using Echopac to measure peak radial systolic strain rate,peak diastolic rate,the segmental total rotational degrees,then anesthesia,thoracotomy,ligation artery,closed chest,after 10 miniutes same indicator preoperative,and...
Objective: To discuss the feasibility and safety of modified side overlap with fundoplication by Yamashita (mSOFY) in laparoscopic proximal gastrectomy. Methods: Using method descriptive case series study, clinical data 9 patients upper gastric cancer who successfully performed mSOFY anastomosis from March 2022 to October Affiliated Huaian No.1 People's Hospital Nanjing Medical University were retrospectively analyzed.The reconstruction steps are as follows: (1) Make a small incision on...
Objective: To investigate right ventricular function in patients with pneumoconiosis, and to provide a basis for quantitative diagnosis treatment of pneumoconiosis clinical practice. Methods: A total 43 who were hospitalized consecutively Shijiazhuang Prevention Treatment Center Occupational Diseases from May 2015 2016 enrolled, according the stage they divided into I group 16 patients, II 14 III 13 patients. healthy subjects enrolled as control group. Echocardiography was performed relevant...
Abstract Background: This study investigated the value of layer-specific strain analysis by twodimensional speckle tracking echocardiography (2D-STE) for evaluating left ventricular (LV) systolic function and synchrony in maintenance hemodialysis (MHD) patients. Methods: A total 34 MHD patients 35 healthy controls were enrolled this study. Dynamic images collected at LV apical long-axis, four- twochamber, short-axis views basal, middle, segments. The layerspecific (LST) was used to analyze...
Abstract Background: This study investigated the value of layer-specific strain analysis by two-dimensional speckle tracking echocardiography (2D-STE) for evaluating left ventricular (LV) systolic function and synchrony in maintenance hemodialysis (MHD) patients. Methods: A total 34 MHD patients 35 healthy controls were enrolled this study. Dynamic images collected at LV apical long-axis, four- two- chamber, short-axis views basal, middle, segments. The (LST) was used to analyze longitudinal...
Abstract Background: This study investigated the value of layer-specific strain analysis by twodimensional speckle tracking echocardiography (2D-STE) for evaluating left ventricular (LV) systolic function and synchrony in maintenance hemodialysis (MHD) patients. Methods: A total 34 MHD patients 35 healthy controls were enrolled this study. Dynamic images collected at LV apical long-axis, four- twochamber, short-axis views basal, middle, segments. The layerspecific (LST) was used to analyze...