A5038643333- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Catalytic Cross-Coupling Reactions
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metal complexes synthesis and properties
- Synthesis and biological activity
- Catalytic C–H Functionalization Methods
- Synthetic Organic Chemistry Methods
- Click Chemistry and Applications
- Asymmetric Hydrogenation and Catalysis
- Multicomponent Synthesis of Heterocycles
- Carbon dioxide utilization in catalysis
- Chemical Synthesis and Analysis
- Computational Drug Discovery Methods
- Synthesis and Biological Evaluation
- Quinazolinone synthesis and applications
- Antimicrobial agents and applications
- Microwave-Assisted Synthesis and Applications
- Free Radicals and Antioxidants
- Magnetism in coordination complexes
- Organometallic Complex Synthesis and Catalysis
- Olfactory and Sensory Function Studies
- Coordination Chemistry and Organometallics
- Synthesis and Characterization of Heterocyclic Compounds
- Neuroendocrine regulation and behavior
Sivas Cumhuriyet Üniversitesi
2015-2025
Université de Strasbourg
2011-2025
Centre National de la Recherche Scientifique
2011-2025
Sivas State Hospital
2025
Netherlands Institute for Neuroscience
2022-2023
Ordu University
2022
Inonu University
2005-2021
Ahi Evran University
2017
Institut de Chimie de Strasbourg
2015
In every day, new nanoparticles have been synthesized, and their properties evaluated since unique physical chemical properties, which are very different from the precursors. Nanoscience also has significant advances in obtaining environmentally friendly sustainable products. Iron oxide nanoparticles, one of metal forms properties. recent years, iron successfully synthesized various plant species using green synthesis pathways analyzed for bioactivity this study, were a completely...
A series of novel silver( i )-NHC complexes are synthesized and characterized. The anticandidal activity some was found to be similar that Flucanozol.
Two series of bis(1-alkylbenzimidazole)silver(I) nitrate and bis(1-alkyl-5,6-dimethylbenzimidazole)silver(I) complexes, in which the alkyl substituent is either an allyl, a 2-methylallyl, isopropyl or 3-methyloxetan-3-yl-methyl chain, were synthesized fully characterized. The eight N-coordinated silver(I) complexes screened for both antimicrobial activities against Gram-negative (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter baumannii) Gram-positive...
Benzimidazole type N‐heterocyclic carbene molecules and their metal complexes have well‐known biological activity. Elemental silver also antibacterial antifungal In this study, with 1‐allyl 5,6‐dimethylbenzimidazolium derivative ligands were analyzed for antimicrobial antibiofilm activities. Additionally, bovine serum albumin (BSA) binding properties of the by spectrophotometric methods, details interactions BSA investigated molecular docking methods. While salts showed moderate activity,...
Abstract Three imidazolium salts based on a rigid resorcinarene platform ( 1 – 3 ) were synthesised and used as catalyst precursors in the Suzuki–Miyaura cross‐coupling of aryl halides with phenylboronic acid. In these pro‐carbene ligands, heterocyclic moiety has one N atom connected to C2 resorcinolic ring, other is substituted by an alkyl group (R= n ‐propyl, iso benzyl). The methinic C atoms macrocyclic core are all pentyl group. best catalytic performances obtained using imidazolium/Pd...
Two bis-ruthenium(II) complexes, namely N,N'-{5,17-diamino-4(24),6(10),12(16),18(22)-tetramethylenedioxy-2,8,14,20-tetrapentylresorcin[4]arene}-bis-[dichloro-(p-cymene)-ruthenium(II)] (1) and N,N'-{5,11-diamino-4(24),6(10),12(16), 18(22)-tetramethylenedioxy-2,8,14,20-tetrapentylresorcin[4]arene}-bis-[dichloro-(p-cymene)-ruthenium(II)] (2) were synthesized tested as catalysts in the N-alkylation of primary amines with arylmethyl alcohol using green "hydrogen borrowing" methodology. The...
In this article, direct N ‐alkylation reactions of amines with alcohols derivatives have been investigated. For purpose, a new series ruthenium (II) complexes bearing N‐coordinated benzimidazole synthesized and fully characterized by elemental analysis, FT‐IR, 1 H NMR and, 13 C spectroscopies. Additionally, the structures 2b 2c confirmed X‐ray crystallography. Although N‐alkylating reaction is usually performed in toluene, catalytic study 2a‐d has carried out no additional solvent alcohol...
The importance of organometallic complexes in cancer biology has attracted attention recent years. In this paper, we look for the vitro cytotoxic capability novel benzimidazole-based N-heterocyclic carbene (NHC) precursor (1) and its Ag(I)-NHC complex (2). For purpose, these (2) was characterized by spectroscopic techniques (1H, 13C{1H} nuclear magnetic resonance (NMR), Fourier-transform infrared spectroscopy (FT-IR)). Then, activities NHC were investigated against MCF-7, MDA-MB-231 human...
Encephalitozoon intestinalis is an opportunistic microsporidian parasite that primarily infects immunocompromised individuals, such as those with HIV/AIDS or undergoing organ transplantation. Leishmaniasis responsible for parasitic infections, particularly in developing countries. The disease has not been effectively controlled due to the lack of effective vaccine and affordable treatment options. Current options E. infection leishmaniasis are limited often associated adverse side effects....
Abstract Three resorcinarene‐cavitands bearing a 3‐R‐1‐imidazolylium substituent (R = alkyl) grafted to the wider rim of cavitand ( 1–3 ) were assessed in Kumada–Tamao–Corriu cross‐coupling aryl halides with arylmagnesium halides. Their combination [Ni(cod) 2 ] (cod 1,5‐cyclooctadiene; 1:1 stoichiometry) resulted highly efficient catalysts, activities which varied following order: R n ‐propyl 1 < isopropyl ≈ benzyl 3 ). A remarkable turnover frequency 60400 mol(ArX) mol(Ni) –1 h was...
Abstract Unsymmetrical imidazolium salts, each having one nitrogen atom (N1) substituted by a cavity‐shaped TPR group (TPR = 2,8,14,20‐tetrapentylresorcinaren‐5‐yl), were tested in situ as proligands for the copper‐catalysed allylic arylation of cinnamyl bromide with arylmagnesium halides. The catalytic systems produced mixtures linear (l) and branched (b) arylated compounds variable proportions, b/l ratio being highest (78:22) most crowded salt used, namely that which second (N2) was...
In this study, we synthesized five new PEPPSI-type Pd-NHC complexes with high yields around 78–83%. The structures of all were characterized by FT-IR, 1H NMR, and 13C{1H} NMR spectroscopies. Further, the structure 2c was determined X-ray crystallography. single-crystal shows that coordination geometry Pd is distorted square planar. efficient catalysts for direct C5-arylation 2-n-butylthiazole, 2-n-butylfuran, 2-n-butylthiophene various aryl-bromides showed catalytic activity arylation...