- Aquaculture Nutrition and Growth
- Polysaccharides Composition and Applications
- Protein Hydrolysis and Bioactive Peptides
- Hearing, Cochlea, Tinnitus, Genetics
- Quinazolinone synthesis and applications
- Seaweed-derived Bioactive Compounds
- Nanocomposite Films for Food Packaging
- Synthesis and biological activity
- Polysaccharides and Plant Cell Walls
- Meat and Animal Product Quality
- Congenital heart defects research
- Click Chemistry and Applications
- Antioxidant Activity and Oxidative Stress
- Cancer therapeutics and mechanisms
- Genetics and Neurodevelopmental Disorders
- RNA and protein synthesis mechanisms
- Silicone and Siloxane Chemistry
- Medicinal Plants and Neuroprotection
- Thermal properties of materials
- Postharvest Quality and Shelf Life Management
- Free Radicals and Antioxidants
- Advanced Nanomaterials in Catalysis
- Seed and Plant Biochemistry
- Biochemical and biochemical processes
- Metal complexes synthesis and properties
Centre of Biotechnology of Sfax
2018-2023
University of Sfax
2014-2023
National Engineering School of Tunis
2014-2016
SnO₂ aerogel/reduced graphene oxide (rGO) nanocomposites were synthesized using the sol⁻gel method. A homogeneous dispersion of (GO) flakes in a tin precursor solution was captured three-dimensional network aerogel matrix and successively underwent supercritical alcohol drying followed by situ thermal reduction GO, resulting aerogel/rGO nanocomposites. The chemical interaction between GO functional groups confirmed peak shift Fourier transform infrared spectra change optical bandgap diffuse...
The present study reports on the extraction of astaxanthin from shrimp processing by-products using corn oil. Its antioxidant activities at different concentrations were evaluated various assays, including DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging (IC50 = 6.3 μg/mL), reducing power, β-carotene bleaching 20.4 μg/mL) and total capacity assays. Interestingly, extract showed strong activity. was added to marinated chicken steaks as a natural antioxidant, samples stored for 7 days...
Silica aerogels possess low thermal conductivity but have a brittle nature, while their polymers tend to exhibit enhanced mechanical properties. In this study, we introduce new approach overcoming property of silica aerogels. Polypropylene/silica aerogel composites were prepared by thermally induced phase separation followed supercritical CO₂ drying method. was formed onto polypropylene scaffold using two-step sol-gel process with methyltrimethoxysilane as the precursor. Enhancement...
Background: This present research highlight the phytochemical profile, antioxidant, antimicrobial, antimutagenic and antiproliferative activities of an essential oil extracted from Corchorus olitorius L. flowers leaf (COFL), aromatic plant widely distributed in Tunisia used as a traditional food plant. Salmonella typhimurium Gas chromatography/ mass spectrometry was to determine composition COFL (COFL-EO). Forty-three components were identified main compounds benzaldehyde (56%), methyl...
Abstract Herein we report that 4‐aminopyrimidine‐5‐carbonitriles 3 a – i were efficiently synthesized by reacting suitable 2‐(ethoxyalkylene)malononitriles 1 c with easily available amidine hydrochlorides 2 d , in good yields using simple synthetic scheme. To predict their pharmacological properties comprehensive silico analysis was conducted. Consequently, appropriate compounds h screened for antiproliferative activity against two colorectal‐cancer‐cell lines and one lung cancer cell line....
The mutations concerned with non-small cell lung cancer involving epidermal growth factor receptor of tyrosine kinase family have primarily targeted. In this study, we employed a scalable high-throughput virtual screening (HTVS) framework and targeted compound library over 50.000 Erlotinib-derived compounds as noncovalent reversible EGFR
Abstract Background In the Tunisian population, molecular analysis of hearing impairment remains based on conventional approaches, which makes task laborious and enormously expensive. Exploration etiology Hearing Impairment early diagnosis causal mutations by next‐generation sequencing help significantly alleviate social economic problems. Methods We elaborated a custom SureSelect QXT panel for coding sequences 42 genes involved in isolated or along with defects retina, thyroid, kidneys....
Hereditary hearing impairment (HI) is a common disease with the highest incidence among sensory defects. Several genes have been identified to affect stereocilia structure causing HI, including unconventional myosin3A. Interestingly, we noticed that variants in MYO3A gene previously found cause variable HI onset and severity. Using clinical exome sequencing, novel pathogenic variant p.(Lys50Arg) kinase domain (MYO3A-KD). Previous vitro studies supported its damaging effect as ‘kinase-dead’...