A5030471414- Inflammatory Bowel Disease
- Gastrointestinal disorders and treatments
- Microscopic Colitis
- Diverticular Disease and Complications
- Gastrointestinal Bleeding Diagnosis and Treatment
- Eosinophilic Esophagitis
- Biosimilars and Bioanalytical Methods
- Colorectal Cancer Screening and Detection
- Autoimmune and Inflammatory Disorders
- Gastric Cancer Management and Outcomes
- Appendicitis Diagnosis and Management
- Immunodeficiency and Autoimmune Disorders
- Helicobacter pylori-related gastroenterology studies
- Pharmaceutical studies and practices
- Gastrointestinal Tumor Research and Treatment
- Celiac Disease Research and Management
- Gut microbiota and health
- Pharmacological Effects of Natural Compounds
- Artificial Intelligence in Healthcare and Education
- Pregnancy and Medication Impact
- COVID-19 Clinical Research Studies
- Spondyloarthritis Studies and Treatments
- COVID-19 and healthcare impacts
- Rheumatoid Arthritis Research and Therapies
- Reproductive System and Pregnancy
Sheba Medical Center
2016-2025
Tel Aviv University
2016-2025
Assuta Medical Center
2024-2025
Ben-Gurion University of the Negev
2023-2024
Academic College of Tel Aviv-Yafo
2024
Hadassah
2023
University of Bologna
2021
Hospital Universitario de La Princesa
2021
Clinical Trial Investigators
2021
University Gastroenterology
2005-2020
New fecal microbiota for cancer patients The composition of the gut microbiome influences response to immunotherapies. Baruch et al. and Davar report first-in-human clinical trials test whether transplantation (FMT) can affect how metastatic melanoma respond anti–PD-1 immunotherapy (see Perspective by Woelk Snyder). Both studies observed evidence benefit in a subset treated patients. This included increased abundance taxa previously shown be associated with anti–PD-1, CD8 + T cell...
The field of gastroenterology (GI) is constantly evolving. It essential to pinpoint the most pressing and important research questions. To evaluate potential chatGPT for identifying priorities in GI provide a starting point further investigation. We queried on four key topics GI: inflammatory bowel disease, microbiome, Artificial Intelligence GI, advanced endoscopy GI. A panel experienced gastroenterologists separately reviewed rated generated questions scale 1-5, with 5 being relevant...
Patients frequently have concerns about their disease and find it challenging to obtain accurate Information. OpenAI's ChatGPT chatbot (ChatGPT) is a new large language model developed provide answers wide range of questions in various fields. Our aim evaluate the performance answering patients' regarding gastrointestinal health.To questions, we used representative sample 110 real-life questions. The provided by were rated consensus three experienced gastroenterologists. accuracy, clarity,...
Background Artificial intelligence, particularly chatbot systems, is becoming an instrumental tool in health care, aiding clinical decision-making and patient engagement. Objective This study aims to analyze the performance of ChatGPT-3.5 ChatGPT-4 addressing complex ethical dilemmas, illustrate their potential role care while comparing seniors’ residents’ ratings, specific question types. Methods A total 4 specialized physicians formulated 176 real-world questions. 8 senior residents...
Mucosal healing (MH) and deep remission (DR) are associated with improved outcomes in Crohn's disease (CD). However, most of the current data pertain to colonic MH DR, whereas evidence regarding prevalence impact small bowel (SB) is scarce. The aim this study was evaluate SBMH DR quiescent SBCD.Patients known SBCD clinical (CDAI<150) or mild symptoms (CDAI<220) were prospectively recruited underwent video capsule endoscopy after verification SB patency. Inflammation quantified using Lewis...
Background: The integration of artificial intelligence (AI) into healthcare has opened new avenues for enhancing patient care and clinical research. In gastroenterology, the potential AI tools, specifically large language models like ChatGPT, is being explored to understand their utility effectiveness. Objectives: primary goal this systematic review assess various applications, ascertain benefits, identify limitations utilizing ChatGPT within realm gastroenterology. Design: Through a...
CT-P13 subcutaneous (SC), an SC formulation of the intravenous (IV) infliximab biosimilar IV, creates a unique exposure profile. The LIBERTY studies aimed to demonstrate superiority vs placebo as maintenance therapy in patients with Crohn's disease (CD) and ulcerative colitis (UC).
See also: Commentaire de travail A. Lahat et al., pp. 521Endoscopy 2007; 39(06): 578-578DOI: 10.1055/s-0032-1306944
Background and Aims: Inflammatory bowel disease (IBD) patients suffer from significant morbidity diminished life quality. The plant cannabis is beneficial in various gastrointestinal diseases, stimulating appetite causing weight gain. Our aims were to assess whether treatment with inhaled improves quality of life, activity promotes gain these patients. Methods: Patients long-standing IBD who prescribed included. Two questionnaires indexes performed, patient’s body was measured before...
Colonic diverticulosis is a common condition with obscure pathogenesis. Obesity, hyperlipidemia and hypertension have been demonstrated to increase the risk of complicated diverticular disease, but impact metabolic factors on prevalence uncomplicated has not clearly determined.The aim study was examine obesity syndrome colonic diverticulosis.This retrospective case-control included patients aged 40-85 years who were followed up by Institute Medical Screening in Israel underwent colonoscopy...
OBJECTIVES: Adalimumab is usually self-injected at home, making prospective serial-sampling studies challenging and scarce. This has led to a gap in knowledge about evolution of anti-adalimumab antibodies (AAAs) over time its correlation with clinical inflammatory outcomes. METHODS: A program for home visits by physicians induction, every 3 months event relapse, was established prospectively Crohn's disease (CD) patients. At each visit, patients' scores were determined sera obtained...
The classification of Crohn's disease (CD) is usually determined at initial diagnosis and frequently based on ileocolonoscopic cross-sectional imaging data. Advanced endoscopic techniques such as small-bowel video capsule endoscopy (VCE) magnetic resonance enterography (MRE) may provide additional data regarding extent phenotype. Our aim was to examine whether VCE or MRE performed after the alter original classification. Consecutive patients with known CD in clinical remission mild were...
Crohn's disease (CD) is a chronic relapsing-remitting gut inflammatory disorder with heterogeneous unpredictable course. Dysbiosis occurs in CD; however, whether microbial dynamics quiescent CD are instrumental increasing the risk of subsequent flare remains undefined.We analyzed long-term composition prospective observational cohort patients (45 cases, 217 samples) over 2 years or until clinical occurred, aiming to identify changes microbiome precede and predict relapse. Machine learning...
OBJECTIVES: Despite encouraging data gathered in inflammatory bowel diseases (IBD) patients, Vedolizumabs' (VDZ) safety profile pregnancy is not established. DESIGN: Data of 330 consecutive pregnancies with IBD was prospectively collected. RESULTS: Women were treated with: VDZ (n = 24), anti-tumor necrosis factors 82) or conventional therapy 224). Gravidity and parity similar among the 3 groups. The group comprised mostly Crohn's disease patients who all naïve to biological treatment. They...
Capsule endoscopy is an important modality for monitoring of Crohn's disease. Recently, a novel panenteric capsule, PillCam (Medtronic, USA), was approved use. No quantitative index inflammation this method currently available. This sub-study prospective randomized controlled Comprehensive individUalized pRoactive ThErapy Disease trial (CURE-CD) which aimed to compare the correlation and reliability score with existing small bowel capsule Lewis inflammatory score.The study cohort included...