A5101941435- Oral microbiology and periodontitis research
- Dental Health and Care Utilization
- Dental Erosion and Treatment
- Dental materials and restorations
- Oral Health Pathology and Treatment
- Oral and gingival health research
- Salivary Gland Disorders and Functions
- Dental Anxiety and Anesthesia Techniques
- Dental Radiography and Imaging
- HIV/AIDS oral health manifestations
- Fluoride Effects and Removal
- Periodontal Regeneration and Treatments
- Gut microbiota and health
- Occupational health in dentistry
- Retinal and Optic Conditions
- Medical Imaging and Analysis
- Retinal Diseases and Treatments
- Antimicrobial Peptides and Activities
- Tattoo and Body Piercing Complications
- Dental Implant Techniques and Outcomes
- Infective Endocarditis Diagnosis and Management
- Laser Applications in Dentistry and Medicine
- Acupuncture Treatment Research Studies
- RNA modifications and cancer
- Peptidase Inhibition and Analysis
Procter & Gamble (United States)
2014-2024
Weatherford College
2020
Renmin Hospital of Wuhan University
2019
Wuhan University
2008-2019
Qingdao University
2017
Affiliated Hospital of Qingdao University
2017
Jiaxing University
2012
First Affiliated Hospital of Xinjiang Medical University
2011
Xinjiang Medical University
2011
University of Ottawa
2010
Oral rinses containing chemotherapeutic agents, such as cetylpyridinium chloride (CPC), can alleviate plaque-induced gingival infections, but how oral microbiota respond to these treatments in human population remains poorly understood. Via a double-blinded, randomised controlled trial of 91 subjects, the impact CPC-containing on supragingival plaque was investigated experimental gingivitis, where after 21-day period dental prophylaxis achieve healthy gingivae, received either CPC or water...
Background: Porphyromonas gingivalis, Bacteroides forsythus , and Actinobacillus actinomycetemcomitans have been described as periodontopathic bacteria, their presence in subgingival pockets can lead to development of periodontal disease. Until now, clinical parameters used evaluate the effect conventional treatment without microbiological parameters. The present study examined effects initial therapy using DNA probes polymerase chain reaction (PCR). Methods: Twenty‐six patients with...
Plaque-induced gingivitis can be alleviated by various treatment regimens. To probe the impacts of anti-gingivitis treatments on plaque microflora, here a double blinded, randomized controlled trial 91 adults with moderate was designed two regimens: brush-alone and brush-plus-rinse treatment. In later group, more reduction in both Plaque Index (TMQHI) Gingival (mean MGI) at Day 3, 11 27 evident, dramatic changes were found between baseline other time points for supragingival microbiota...
Dentinal hypersensitivity is a common complaint among dental patients. Recently, novel 0.454% stabilized stannous fluoride dentifrice containing sodium hexametaphosphate (SHMP) was introduced that offers desensitizing benefit. This trial conducted to assess the efficacy of this new relative control dentifrice.This double-blind, parallel-group, randomized clinical according American Dental Association (ADA) Guidelines for Acceptance Products Treatment Hypersensitivity. Ninety subjects who met...
Numerous studies have investigated the effects of stannous ions on specific microbes and their efficacy in reducing dental plaque. Nonetheless, our understanding impact oral microbiome is still a subject ongoing exploration. Therefore, this study sought to evaluate stannous-containing sodium fluoride dentifrice comparison zinc-containing control group intact, healthy biofilms. Utilizing novel 2bRAD-M approach for species-resolved metagenomics, FISH/CLSM with probes targeting periodontal...
Abstract Objective: Stannous fluoride is a broad‐spectrum anti‐microbial agent that has been used in dentistry as chemical adjunct to prevent dental caries and gingivitis. The objective of this study was assess the anti‐gingivitis efficacy stabilized 0.454% stannous fluoride/sodium hexametaphosphate dentifrice relative negative control. Methods: This randomized, 6‐month, double‐blind, parallel‐group gingivitis conducted according guidelines for evaluating chemotherapeutic products control...
Abstract Background, aims: This study investigated the prevalence of Bacteroides forsythus , Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans among various periodontitis patients healthy individuals in Japan, correlated it with clinical parameters. Method: Subgingival plaque samples were collected from 21 adult (AP), 8 rapidly progressive (RPP) 15 individuals. Results: The frequency detected culture was as follows: B. found 47.6% AP sites 37.5% RPP sites. P. identified 64.3%...
Bacteremia and systemic inflammatory markers are associated with periodontal diseases may be linking mechanisms between these conditions. We hypothesized that in the development of gingival inflammation, inflammation bacteremia would increase.To study effect on markers, we recruited 80 subjects to participate an experimental gingivitis study. Subjects were stratified based gender, smoking number bleeding sites then randomized one two groups: control group (n = 40) or 40). conducted oral...
Abstract Background Dentin hypersensitivity (DH) is common, particularly among periodontal patients. This trial evaluated magnitude of desensitizing benefit, onset action, and complete relief three dentifrices with distinct technologies. Methods Healthy adults DH were enrolled randomized to one four in this randomized, controlled, double‐blind trial: marketed potassium nitrate (KNO 3 ), stannous fluoride (SnF 2 experimental 1.5% oxalate, or negative control (NC) monofluorophosphate....
Background: The expression of leukotoxin varies among Actinobacillus actinomycetemcomitans strains and is dependent in part on the structure ltx promoter region. Highly leukotoxic strains, characterized by a 530 base pair (bp) deletion within promoter, have been associated with juvenile periodontitis United States Europe. In present study, we analyzed to elucidate whether A. from Japanese patients exhibits highly toxic phenotype. Methods: Forty‐five including 43 clinical isolates, strain...
Background: Antimicrobial agents such as stannous fluoride and triclosan have been incorporated into dentifrice formulations shown to be effective in reducing gingivitis. The objective of this study was compare the anti‐gingivitis efficacy a 0.454% fluoride/sodium hexametaphosphate positive control triclosan/copolymer dentifrice. Methods: This 6‐month, randomized, double‐masked, parallel‐group conducted according American Dental Association guidelines for evaluating chemotherapeutic products...
Abstract Objective To compare the enamel protection efficacy of a stabilized stannous fluoride (SnF 2 ) dentifrice to sodium (NaF)/triclosan following acidic erosive challenge. Methods In this in situ , randomized, controlled, double‐blind, two‐treatment, four‐period crossover clinical trial, subjects wore an appliance fitted with human samples 6 h day −1 during each 15‐day treatment period. Twice they swished their assigned slurry: 0.454% SnF /0.077% NaF or 0.32% NaF/0.3% triclosan. After...
P eriodontitis, similar to other infectious diseases , is known progress as chronic inflammation with recurrent acute phases. The purpose of this study was clarify the microbiological composition phase and compare bacterial flora that comparable periodontal pockets. We also evaluated effect application minocycline gel locally on change in microflora Microbial from subgingival pockets 28 patients periodontitis 12 a control were investigated by various culture methods including TS blood agar...
The aim of these investigations was to assess the ability two fluoride dentifrices protect against initiation and progression dental erosion using a predictive in vitro cycling model human situ prevention clinical trial for verification effectiveness. A stabilized stannous (SnF2) dentifrice (0.454 % SnF2 + 0.077 sodium [NaF]; total F = 1450 ppm F) [dentifrice A] monofluorophosphate [SMFP]/arginine (1.1 SMFP 1.5 arginine; B] were tested 5-day 10-day randomized, controlled, double-blind,...
Oral Actinobacillus actinomycetemcomitans strains are serologically classified into 5 distinct groups, a to e. We examined the distribution of A. serotypes in Japanese patients with periodontitis. A total 157 clinical isolates from diseased sites 39 periodontitis were serotyped by using serotype‐specific rabbit antisera against. a, b, c, d and e strains. In immunodiffusion assay, autoclaved extracts 42, 6, 39, 9 41 reacted antisera, respectively. Although 37 infected serotype strain, 2...