A5037042809- Antimicrobial Resistance in Staphylococcus
- Antibiotic Resistance in Bacteria
- Bacterial Identification and Susceptibility Testing
- Bacterial biofilms and quorum sensing
- Antibiotics Pharmacokinetics and Efficacy
- Pneumonia and Respiratory Infections
- Streptococcal Infections and Treatments
- Antibiotic Use and Resistance
- Infective Endocarditis Diagnosis and Management
- Urinary Tract Infections Management
- Antifungal resistance and susceptibility
- Pharmaceutical and Antibiotic Environmental Impacts
- Urological Disorders and Treatments
- Plant Pathogenic Bacteria Studies
- Mycobacterium research and diagnosis
- Enterobacteriaceae and Cronobacter Research
- Microbial Metabolism and Applications
- Kidney Stones and Urolithiasis Treatments
- Sexual function and dysfunction studies
- Infections and bacterial resistance
- Orthopedic Infections and Treatments
- Ureteral procedures and complications
- Probiotics and Fermented Foods
- Cystic Fibrosis Research Advances
- Vibrio bacteria research studies
University of Catania
2016-2025
Policlinico Universitario di Catania
2005-2025
University of Perugia
2023-2024
Fleury S.A. (Brazil)
2020
University of Modena and Reggio Emilia
2008-2019
Hospital Mãe de Deus
2013-2018
University of Florence
2017
Azienda Ospedaliero-Universitaria Careggi
2017
Bio-Medical Science (South Korea)
2013-2014
Università Cattolica del Sacro Cuore
2013
Reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR) is the gold standard method for diagnosis of COVID‑19 infection. Due to pre‑analytical and technical limitations, samples with low viral load are often misdiagnosed as false‑negative samples. Therefore, it important evaluate other strategies able overcome limits RT‑qPCR. Blinded swab from two individuals diagnosed positive negative were analyzed by droplet digital PCR (ddPCR) RT‑qPCR in order assess sensitivity both...
The use of bacteria as probiotics is in continuous development, thanks to their capacity maintain or restore a host's natural microbiome by interference with and/or inhibition other microorganisms mediated antimicrobial peptide production such bacteriocins. In the oral cavity, Streptococcus salivarius, non-pathogenic and predominant species, one major bacteriocin producers that able coexist this environment reduce frequency colonization main pathogens involved upper respiratory tract...
Development of in vivo daptomycin resistance (DAP-R) among Staphylococcus aureus clinical isolates, association with treatment failures, has become a major therapeutic problem. This issue is especially relevant to methicillin-resistant S. (MRSA) strains the context invasive endovascular infections. In current study, we used three well-characterized and clinically-derived DAP-susceptible (DAP-S) vs. resistant MRSA strain-pairs elucidate potential genotypic mechanisms DAP-R phenotype....
Abstract The healthy vaginal microbiota is dominated by Lactobacillus spp., which provide an important critical line of defense against pathogens, as well giving beneficial effects to the host. We characterized L . gasseri 1A‐TV, fermentum 18A‐TV, and crispatus 35A‐TV, from premenopausal women, for their potential probiotic activities. antimicrobial 3 strains combination clinical urogenital bacteria were evaluated together with activities metabolites produced cell‐free supernatants (CFSs)....
The use of natural compounds with biocidal activity to fight the growth bacteria responsible for foodborne illness is one main research challenges in food sector. This study reports preparation and physicochemical characterization chitosan nanoparticles loaded Thymus capitatus (Th-CNPs) Origanum vulgare (Or-CNPs) essential oils. nanosystems were obtained by ionotropic gelation technique high encapsulation efficiency (80–83%) loading capacity (26–27%). Nanoparticles showed a spherical shape,...
Management of patients with infections caused by multidrug-resistant organisms is challenging and requires a multidisciplinary approach to achieve successful clinical outcomes. The aim this paper provide recommendations for the diagnosis optimal management these infections, focus on targeted antibiotic therapy. document was produced panel experts nominated five endorsing Italian societies, namely Association Clinical Microbiologists (AMCLI), Group Antimicrobial Stewardship (GISA), Society...
Among the bacterial species included in ESKAPE group, Acinetobacter baumannii is of great interest due to its intrinsic and acquired resistance many antibiotics ability infect different body regions. Cefiderocol (FDC) a novel cephalosporin that active against Gram-negative bacteria, with promising efficacy for A. infections, but some studies have reported therapeutic failures even presence susceptible strains. This study aims investigate interactions between FDC 10 strains susceptibilities...
Intensive care units constitute a critical setting for the management of infections. The patients' fragilities and spread multidrug-resistant microorganisms lead to relevant difficulties in care. Recent epidemiological surveys documented Gram-negative bacteria supremacy among intensive unit (ICU) infection aetiologies, accounting numerous isolates. Regarding this specific setting, clinical microbiology support holds crucial role definition diagnostic algorithms. Eventually, complete patient...
ABSTRACT Carbapenem-resistant Pseudomonas aeruginosa and Acinetobacter spp. represent major threats have few approved therapeutic options. Non-fermenting Gram-negative isolates were collected from hospitalized inpatients 49 sites in 6 European countries between 01 January 2020 31 December underwent susceptibility testing against cefiderocol β-lactam/β-lactamase inhibitor combinations. Meropenem-resistant (MIC >8 mg/L), cefiderocol-susceptible analyzed by PCR, cefiderocol-resistant...
The spread of antibiotic resistant bacteria (ARB) and resistance genes (ARGs) in humans, animals environment is a growing threat to public health. Wastewater treatment plants (WWTPs) are crucial mitigating the risk environmental contamination by effectively removing contaminants before discharge. However, persistence ARB ARGs even after challenge for management water system. To comprehensively assess antimicrobial dynamics, we conducted one-year monitoring study three WWTPs central Italy,...
ABSTRACT Carbapenem-resistant Enterobacterales represent a major health threat and have few approved therapeutic options. isolates were collected from hospitalized inpatients 49 sites in six European countries (1 January–31 December 2020) underwent susceptibility testing to cefiderocol β-lactam/β-lactamase inhibitor combinations. Meropenem-resistant (MIC >8 mg/L) cefiderocol-susceptible analyzed by PCR, cefiderocol-resistant whole-genome sequencing, identify resistance mechanisms....
Klebsiella pneumoniae represent a common invasive infection etiological agent, whose potential carbapenem-resistance and hypermucoviscosity complicate the patient's management. Infection development often derives from gastrointestinal colonization; thus, it is fundamental to monitor asymptomatic K. colonization through surveillance protocols, especially for intensive care immunocompromised patients. We described six-month routine screening protocol Policlinico of Catania (Italy), while blood...