- Frailty in Older Adults
- Nutrition and Health in Aging
- Body Composition Measurement Techniques
- Intensive Care Unit Cognitive Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Anesthesia and Neurotoxicity Research
- Hip and Femur Fractures
- Hemoglobinopathies and Related Disorders
- Long-Term Effects of COVID-19
- Cardiovascular and exercise physiology
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Systemic Lupus Erythematosus Research
- Delphi Technique in Research
- Anesthesia and Sedative Agents
- Nutritional Studies and Diet
- Complement system in diseases
University of Birmingham
2020-2024
University Hospitals Birmingham NHS Foundation Trust
2020-2024
Centre Hospitalier Universitaire Ibn Rochd
2022
Queen Elizabeth Hospital
2020
Sandwell & West Birmingham Hospitals NHS Trust
2017
Birmingham Women’s and Children’s NHS Foundation Trust
2017
Aim Acute sarcopenia is defined by the development of incident (low muscle quantity/quality and function) within 6 months a stressor event. However, outcome measures for clinical trials have not been validated. This study aimed to characterize changes in quantity, quality, strength, physical function during after hospitalization. Methods Patients aged ≥70 years admitted elective colorectal surgery, emergency abdominal surgery or acute infections were recruited from single university...
Abstract Purpose To assess feasibility of conducting acute sarcopenia research in complex populations hospitalised older adults. Methods Patients ≥ 70 years old were recruited to three cohorts: elective colorectal surgery, emergency (abdominal) medical patients with infections. Participants the cohort preoperative assessment clinic, and acutely admitted participants from surgical wards at Queen Elizabeth Hospital Birmingham. Serial measures muscle quantity (ultrasound quadriceps,...
Objectives This study sets out to ascertain if recognition of delirium impacts on patient outcomes. Design Retrospective cohort study. Setting Unscheduled admissions acute care trust/secondary UK hospitals. Participants Six hundred and fifty-six older adults aged ≥65 years admitted 14 September 2018. Measurements Delirium was ascertained retrospectively from case notes using medical notes. Documented classified as recognised unrecognised delirium. Primary secondary outcome measures measure:...
Background: Dynamic changes in sarcopenia status following stressor events are defined as acute sarcopenia; it is currently unknown how to stratify risk.Methods: Prospective observational study involving elective colorectal surgery, emergency abdominal and medical patients with infections aged ≥70 years-old.Handgrip strength, muscle quantity (ultrasound Bilateral Anterior Thigh Thickness, BATT, Bioelectrical Impedance Analysis), quality (rectus femoris echogenicity) were measured...
Ultrasonography is an emerging non-invasive bedside tool for muscle quantity/quality assessment; Bioelectrical Impedance Analysis (BIA) alternative measure of body composition, recommended evaluation sarcopenia in clinical practice. We set out to assess impact position and exercise upon measures towards protocol standardisation. Healthy volunteers aged 18-35 were recruited. Bilateral Anterior Thigh Thickness (BATT; rectus femoris vastus intermedius), BATT: Subcutaneous Ratio (BATT:SCR),...
To determine the effects of hospitalisation upon frailty and sarcopenia.Prospective cohort study at single UK hospital including adults ≥70 years-old admitted for elective colorectal surgery, emergency abdominal or acute infections. Serial assessments (Fried, Frailty Index, Clinical Scale [CFS]), sarcopenia (handgrip strength, ultrasound quadriceps and/or bioelectrical impedance analysis, gait speed Short Physical Performance Battery) were conducted baseline, 7 days...
Growing research in geriatric medicine is a priority area. Currently, involvement of geriatricians lags behind other specialties. The reasons for this are multifactorial, but lack training infrastructure within higher specialist contributory. This widespread across European countries and internationally. Geriatric Medicine Research Collaborative (GeMRC) offers an opportunity to engage trainees research, regardless their previous individual experiences. Utilising national trainee networks,...
This exploratory study aimed to assess associations of baseline nutritional status and in-hospital step count with muscle quantity, quality, function. Seventy-nine participants aged ≥70 years (mean age 79.1 years, 44.3% female) were recruited (elective colorectal surgery, emergency abdominal general medical patients infections). Baseline nutrition (Mini Nutritional Assessment) (Fitbit Inspire devices) assessed. Ultrasound quadriceps, bioelectrical impedance analysis, physical function...