Julia Howard

ORCID: 0000-0003-1612-2136
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About
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Research Areas
  • Antimicrobial Resistance in Staphylococcus
  • Streptococcal Infections and Treatments
  • Antibiotic Resistance in Bacteria
  • Tuberculosis Research and Epidemiology
  • Bacterial Identification and Susceptibility Testing
  • Fungal Infections and Studies
  • Microbial Metabolism and Applications
  • Mycobacterium research and diagnosis
  • Nail Diseases and Treatments
  • Infective Endocarditis Diagnosis and Management
  • Clostridium difficile and Clostridium perfringens research
  • Plant Pathogenic Bacteria Studies
  • Vibrio bacteria research studies
  • Sepsis Diagnosis and Treatment
  • Bacterial biofilms and quorum sensing
  • Antifungal resistance and susceptibility
  • Diphtheria, Corynebacterium, and Tetanus
  • Escherichia coli research studies
  • Diagnosis and treatment of tuberculosis
  • Otolaryngology and Infectious Diseases
  • Antibiotics Pharmacokinetics and Efficacy
  • Additive Manufacturing and 3D Printing Technologies
  • Infection Control in Healthcare
  • Polymer Foaming and Composites
  • Urinary Tract Infections Management

Canterbury Health Laboratories
2016-2024

Christchurch Hospital
2023-2024

Waikato Regional Council
2023-2024

Pharmac
2024

University of Otago
2024

University of Hawaiʻi at Mānoa
2024

Michigan Medicine
2021

University of Michigan
2020-2021

New Hope Fertility Center
2021

Ann Arbor Center for Independent Living
2020-2021

Patients without human immunodeficiency virus (HIV) are increasingly recognized as being at risk for cryptococcosis. Knowledge of characteristics cryptococcosis in these patients remains incomplete.We conducted a retrospective study 46 Australian and New Zealand hospitals to compare its frequency with HIV describe HIV. between January 2015 December 2019 were included.Of 475 cryptococcosis, 90% (426 475) marked predominance both Cryptococcus neoformans (88.7%) gattii cases (94.3%). Most...

10.1093/cid/ciad321 article EN Clinical Infectious Diseases 2023-05-26

The resistance mechanisms of more than 2,000 aminoglycoside-resistant gram-negative aerobic bacteria were estimated by a method that assigned biochemical mechanism based on susceptibility to selected aminoglycosides. Strains from hospitals in Japan, Formosa, and Korea (the Far East) compared with strains Chile the United States. Of Chile, 90% had an aminoglycoside pattern indicative 3-N-acetyltransferase [AAC(3)-V] enzyme. East, 78% patterns suggesting presence AAC(6') enzymes. In contrast,...

10.1128/aac.28.2.282 article EN Antimicrobial Agents and Chemotherapy 1985-08-01

In 2011 a novel methicillin resistance gene, mecC, was described in human and bovine Staphylococcus aureus isolates. mecC-positive S. is most commonly associated with livestock wildlife populations across Europe particularly prevalent hedgehogs, but only occasionally causes infections. this study we characterize investigate the origin of two isolates containing mecC genes from New Zealand. The were identified patients severe invasion infection as part bacteraemia study. Whole genome...

10.1099/acmi.0.000849.v1 preprint EN cc-by 2024-05-20

Staphylococcus argenteus (SARG) was discovered in 2009 as part of the aureus (SAUR) complex and has been documented from various locations worldwide. In this article we describe genomic features five strains SARG found Christchurch, New Zealand. Isolates were first detected 2019 using MALDI-ToF identification, their identities confirmed whole genome sequencing (WGS). Genomic features, including antimicrobial resistance markers virulence factors compared to other sequences NCBI GenBank. Four...

10.1099/acmi.0.000916.v2 preprint EN cc-by 2025-03-05

Staphylococcus argenteus (SARG) was discovered in 2009 as part of the aureus (SAUR) complex and has been documented from various locations worldwide. In this article we describe genomic features five strains SARG found Christchurch, New Zealand. Isolates were first detected 2019 using MALDI-ToF identification, their identities confirmed whole genome sequencing (WGS). Genomic features, including antimicrobial resistance markers virulence factors compared to other sequences NCBI GenBank...

10.1099/acmi.0.000916.v3 preprint EN 2025-05-07

In 2011, a novel methicillin resistance gene, mecC , was described in human and bovine Staphylococcus aureus isolates. mecC- positive S. is most commonly associated with livestock wildlife populations across Europe particularly prevalent hedgehogs, but only occasionally causes infections. this study, we characterize investigate the origin of two isolates containing genes from New Zealand. The were identified patients severe invasion infections as part an bacteraemia study. Whole-genome...

10.1099/acmi.0.000849.v2 article EN cc-by-nc Access Microbiology 2024-09-01

The objective of this study was to compare the performance an in-house CIM (iCIM) modification with and mCIM for detection carbapenemase production in 149 well characterised isolates (70 producers 79 non-carbapenemase producers). Isolates were tested using CIM, iCIM procedures. gold standard genotypic characterisation by PCR. For Acinetobacter baumannii, sensitivity low (10%) mCIM, 70% but 100% iCIM, a specificity all three. Enterobacterales, three tests Ambler class A B β-lactamases, while...

10.1016/j.jgar.2020.03.021 article EN cc-by-nc-nd Journal of Global Antimicrobial Resistance 2020-04-09

Abstract Xanthomonas axonopodis pv. vasculorum (Xav), the causative agent of sugarcane gumming disease, represents a significant threat to global production due its systemic and destructive nature. Despite economic implications, field-deployable, Xav-specific diagnostic tool has not been developed. This resulted in loop-mediated isothermal amplification (LAMP) assay targeting pelL gene, unique Xav strains, as rapid precise assay. The selection gene was informed by comprehensive silico...

10.1101/2024.02.07.579270 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-02-08

Abstract Introduction The Serratia marcescens enzymes (SMEs) are chromosomally encoded Ambler Class A carbapenem-hydrolysing β-lactamases, which distinctively express resistance to carbapenems while remaining susceptible extended-spectrum cephalosporins. Global reports of SMEs infrequent. Here we describe the isolation an SME-2-producing S. from sputum a patient who was hospitalized at Christchurch Hospital, New Zealand. Methods An immunosuppressed asthmatic presented with shortness breath...

10.1093/jacamr/dlad126 article EN cc-by-nc JAC-Antimicrobial Resistance 2023-11-01

Staphylococcus aureus bacteraemia is associated with significant morbidity and mortality. There evidence that standardised care bundle implementation may improve the rates of appropriate investigations overall management. A S. was introduced at Christchurch Hospital, New Zealand in early 2014. We assessed impact intervention on management outcome bacteraemia.A cohort study cases conducted following introduction. Prospective enrolment post-intervention patients occurred from 1st January 2014...

10.1016/j.infpip.2020.100096 article EN cc-by-nc-nd Infection Prevention in Practice 2020-09-25

We report a case of catheter-associated Elizabethkingia miricola bacteraemia in haemodialysis patient. The patient was 73-year-old home who presented with history recurrent falls and fevers. Blood cultures grew Gram-negative bacilli identified by MALDI-TOF MS (matrix-assisted laser desorption/ionization time-of-flight mass spectrometry 6903 MSP Library) 16S rRNA gene sequencing as E. miricola. is an emerging human pathogen multidrug-resistant, making the choice antimicrobial therapy...

10.1099/acmi.0.000098 article EN cc-by-nc Access Microbiology 2020-02-01
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