A5043448973- Autoimmune and Inflammatory Disorders Research
- Cardiac electrophysiology and arrhythmias
- Respiratory viral infections research
- Rheumatoid Arthritis Research and Therapies
- Kawasaki Disease and Coronary Complications
- Ion channel regulation and function
- Cardiac tumors and thrombi
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- ECG Monitoring and Analysis
- Cardiac and Coronary Surgery Techniques
- Aortic Disease and Treatment Approaches
- Coronary Artery Anomalies
- Cardiac Arrhythmias and Treatments
- Inflammasome and immune disorders
- Immunodeficiency and Autoimmune Disorders
- Pericarditis and Cardiac Tamponade
- RNA regulation and disease
- Central Venous Catheters and Hemodialysis
- Health Promotion and Cardiovascular Prevention
- Clinical practice guidelines implementation
- Connective tissue disorders research
- Skin and Cellular Biology Research
- Obesity, Physical Activity, Diet
- Blood Coagulation and Thrombosis Mechanisms
Antwerp University Hospital
2020-2024
University of Antwerp
2020
Committee on Publication Ethics
2019
Novem (Netherlands)
2019
Universitair Ziekenhuis Brussel
2010-2018
Vrije Universiteit Brussel
2018
Background: The aim of the study was to document cardiovascular clinical findings, cardiac imaging, and laboratory markers in children presenting with novel multisystem inflammatory syndrome associated coronavirus disease 2019 (COVID-19) infection. Methods: This real-time internet-based survey has been endorsed by Association for European Paediatric Congenital Cardiologists Working Groups Cardiac Imaging Cardiovascular Intensive Care. Children 0 18 years age admitted a hospital between...
This study was undertaken to determine the plasma concentration and pharmacokinetic variability of fenfluramine (FFA) its main active metabolite norfenfluramine (norFFA) in relation prevalence adverse effects patients with refractory epilepsy treated FFA. In addition, interaction concomitant antiseizure medications including stiripentol (STP) is studied.Patients were recruited at our center from two open-label sources, an investigator-initiated observational international multicenter...
Abstract Background Brugada Syndrome is an inherited arrhythmogenic disease, characterized by the typical coved type ST-segment elevation in right precordial leads from V1 through V3. The BrugadaDrugs.org Advisory Board recommends avoiding administration of propofol patients with Syndrome. Since prospective studies are lacking, it was purpose this study to assess electrocardiographic effects and etomidate on ST- QRS-segments. In trial, hypothesized that or bolus for induction anesthesia,...
Background: The aim of the study was to document cardiovascular clinical findings, cardiac imaging and laboratory markers in children presenting with novel multisystemic inflammatory syndrome associated COVID-19. Methods: A real-time internet based survey sent via member mailing database for Association European Paediatric Congenital Cardiologists (AEPC) working groups Cardiac Imaging Cardiovascular Intensive Care member. Inclusion criteria 0-18 years admitted hospital between March 1 June...
Multisystem inflammatory syndrome in children (MIS-C) is associated with important cardiovascular morbidity during the acute phase. Follow-up shows a swift recovery of cardiac abnormalities most patients. However, small portion patients has persistent sequelae at mid-term. The goal our study was to assess late outcomes MIS-C.A prospective observational multicenter performed admitted MIS-C and involvement between April 2020 March 2022. A follow-up by NT-proBNP measurement, echocardiography,...
Familial primary desminopathies are usually autosomal dominantly inherited and present at the age of 20 to 40 years with progressive muscle weakness atrophy, cardiomyopathy, cardiac arrhythmias. Cardiac features may precede muscular weakness. Here, we report rare case two siblings presenting a desminopathy pediatric age, due homozygous nonsense variations (c.700G > T [p.Glu234Ter]) in DES, representing an recessive inheritance pattern. The state these variants is expected result complete...
Transcriptome profiling of blood cells is an efficient tool to study the gene expression signatures rheumatic diseases. This aims improve early diagnosis pediatric diseases by investigating patients' and applying machine learning on transcriptome data develop predictive models. RNA sequencing was performed whole collected from children with Random Forest classification models were developed based 48 patients, 46 viral infection, 35 controls classify different disease groups. The performance...
A newborn was diagnosed by echocardiogram with an asymptomatic cardiac mass in the right ventricle after a systolic murmur detected at birth. Nine days birth, presented three syncopal episodes and oxygen desaturation which required resuscitation. The induced complete ventricular outflow tract obstruction. presence of patent foramen oval ductus arteriosus explained absence symptoms Surgery rapidly considered since situation life threatening. tumor successfully resected. mature teratoma...
Brugada syndrome (BrS) is an inherited cardiac arrhythmia with increased risk for sudden death (SCD). About 20% of BrS cases are explained by mutations in the SCN5A gene, encoding main sodium Nav1.5 channel. Here we present a severe case channelopathy caused compound heterozygous mutations. We performed genetic analysis male proband who collapsed during cycling at age two. Because atrial standstill, he received pacemaker and three experienced new collapse left-sided brain stroke. A later ECG...
Abstract We present the case of a premature neonate with pericardial effusion secondary to extravasation total parenteral nutrition from mispositioned/migrated umbilical venous catheter. Emergency pericardiocentesis was complicated by an intrapericardial thrombus, which managed conservatively spontaneous resolution within 24 hours. This illustrates that rare complication thrombus after can be successfully close monitoring in haemodynamically stable paediatric patients.
Long-term cancer survivors treated with anthracycline-containing chemotherapy are at risk for serious cardiotoxicity [7] which can be devastating resulting in morbidity, poor quality of life, and premature mortality.Early detection high-risk patients is considered to the main
Maternal tachycardia is the most frequently occurring cardiac complication during pregnancy. Often administration of drugs required as a treatment. The drug choice intravenously administered adenosine because it considered safe, though there are limited studies regarding safety for foetus with use adenosine.We report conversion maternal atrio-ventricular (AV) nodal reentry pregnancy intravenous whilst continuous electrophysiological foetal monitoring. Four seconds after conversion, tracing...
Introduction Several algorithms have been developed to predict the localization of accessory pathways (AP) in patients with Wolff-Parkinson-White (WPW). The majority these focused on adult population. Boersma et al. an algorithm specifically designed for paediatric Aim We aim compare accuracy predicting AP using according d’Avila and by Boersma. Both are based QRS polarity. Method present our single centre experience children WPW. data was collected retrospectively from April 2007 November...
Isolated cleft of the mitral valve is a very uncommon congenital cause regurgitation.Most clefts involve anterior leaflet while isolated posterior have been anecdotally reported.We present child with Marfan phenotype incompetence due to midline (P2) in leaflet.Marfan syndrome frequently involves causing prolapse.Occurrence may be an extension its involvement.