- Congenital Heart Disease Studies
- Coronary Artery Anomalies
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiomyopathy and Myosin Studies
- Cardiac Imaging and Diagnostics
- Vascular anomalies and interventions
- Pulmonary Hypertension Research and Treatments
- Cardiac Arrhythmias and Treatments
- Parathyroid Disorders and Treatments
- Tracheal and airway disorders
- Cardiovascular Effects of Exercise
- Cardiovascular Issues in Pregnancy
- Infective Endocarditis Diagnosis and Management
- Cardiac tumors and thrombi
- Pericarditis and Cardiac Tamponade
- Kawasaki Disease and Coronary Complications
- Advanced MRI Techniques and Applications
- Mechanical Circulatory Support Devices
- Blood Pressure and Hypertension Studies
- Ultrasound in Clinical Applications
- Viral Infections and Immunology Research
- Eosinophilic Disorders and Syndromes
Bambino Gesù Children's Hospital
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2025
University of Milan
2022
Santobono Children's Hospital
2022
IRCCS Policlinico San Donato
2022
Great Ormond Street Hospital for Children NHS Foundation Trust
2017
Great Ormond Street Hospital
2011-2014
University College London
2011-2014
University of Bologna
2005-2011
Policlinico S.Orsola-Malpighi
2010
Background— Most studies of amyloidotic cardiomyopathy consider as a single entity the 3 main systemic cardiac amyloidoses: acquired monoclonal immunoglobulin light-chain (AL); hereditary, mutated transthyretin-related (ATTRm); and wild-type (ATTRwt). In this study, we compared diagnostic/clinical profiles these types amyloidosis. Methods Results— We conducted longitudinal study 233 patients with clear-cut diagnosis by type amyloidosis (AL, n=157; ATTRm, n=61; ATTRwt, n=15) at 2 large...
Background: The aim of the study was to document cardiovascular clinical findings, cardiac imaging, and laboratory markers in children presenting with novel multisystem inflammatory syndrome associated coronavirus disease 2019 (COVID-19) infection. Methods: This real-time internet-based survey has been endorsed by Association for European Paediatric Congenital Cardiologists Working Groups Cardiac Imaging Cardiovascular Intensive Care. Children 0 18 years age admitted a hospital between...
Background. The pandemic of Novel Coronavirus Disease 2019 (COVID-19) is challenging, given the large number hospitalized patients. Cardiovascular co-morbidities are linked to a higher mortality risk. Thus, patients with Congenital Heart (CHD) might represent high-risk population. Nevertheless, no data about them available, yet. Hence, we conducted nationwide survey assess clinical characteristics and outcomes in congenital heart disease affected by COVID-19. Methods Results. This...
Cardiovascular magnetic resonance (CMR) and computed tomography (CCT) are advanced imaging modalities that recently revolutionized the conventional diagnostic approach to congenital heart diseases (CHD), supporting echocardiography often replacing cardiac catheterization. This is second of two complementary documents, endorsed by experts from Working Group Italian Society Pediatric Cardiology College Cardiac Radiology Medical Interventional Radiology, aimed at giving updated indications on...
To investigate associations between gender and myocardial involvement in systemic amyloidosis, we reviewed all patients presenting 1994 September 2006 our institutional network (100 AL 98 familial transthyretin-related amyloidosis (ATTR) patients, plus 12 elderly men with senile amyloidosis). We focused on echocardiographic descriptors of (height-indexed mean left ventricular (LV) wall thickness, LV mass index), baseline function. Among ATTR female prevalence was lower within the highest...
Transthyretin-related hereditary amyloidosis (ATTR) is genotypically/phenotypically heterogeneous. We investigated myocardial involvement in ATTR a cohort of patients with wide range mutations. Clinical/echocardiographic follow-up 41 consecutive symptomatic from single referral center was analyzed according to TTR mutation. Diagnosis based on histology, immunohistochemistry and genotyping. Median follow up 40 months (range 8–120). Among the 12 different mutations identified, Val30Met found...
The aortic valve (AV) neocuspidization (Ozaki procedure) is a novel surgical technique for AV disease that preserves the natural motion and cardiodynamics of root. In this study, we sought to evaluate, by 4D-flow magnetic resonance imaging, blood flow characteristics after in paediatric patients.Aortic root ascending aorta haemodynamics were evaluated population patients treated with Ozaki procedure; results compared those group operated Ross technique. Cardiovascular studies performed at...
Abstract The aim here was to describe the role of speckle tracking echocardiography (STE), in identifying impairment systolic function children and adolescents with focal myocarditis without reduction ejection fraction. We data from 33 pediatric patients (age 4–17 years) admitted for myocarditis, confirmed by cardiac magnetic resonance (CMR), impaired fraction and/or wall motion abnormalities. All underwent Doppler examination analysis global (G) segmental longitudinal strain (LS) CMR...
Background: The aim of the study was to document cardiovascular clinical findings, cardiac imaging and laboratory markers in children presenting with novel multisystemic inflammatory syndrome associated COVID-19. Methods: A real-time internet based survey sent via member mailing database for Association European Paediatric Congenital Cardiologists (AEPC) working groups Cardiac Imaging Cardiovascular Intensive Care member. Inclusion criteria 0-18 years admitted hospital between March 1 June...
To compare real-time compressed sensing (CS) and standard balanced steady-state free precession (bSSFP) cardiac cine imaging in children.Twenty children (mean age, 15 years ± 5 [SD], range, 7-21 years; 10 male participants) with biventricular congenital heart disease (n = 11) or cardiomyopathy 9) were prospectively included. Examinations performed 1.5-T imagers by using both bSSFP CS sequences all participants. Quantification of ventricular volumes function was for images two readers blinded...