A5025409103- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Congenital Heart Disease Studies
- Cardiac Imaging and Diagnostics
- Cardiomyopathy and Myosin Studies
- Cardiac Structural Anomalies and Repair
- Coronary Artery Anomalies
- Chemotherapy-induced cardiotoxicity and mitigation
- Cardiac Arrhythmias and Treatments
- Aortic Disease and Treatment Approaches
- Cardiovascular Effects of Exercise
- Cardiac pacing and defibrillation studies
- Connective tissue disorders research
- Mitochondrial Function and Pathology
- Congenital heart defects research
- Aortic aneurysm repair treatments
- Mechanical Circulatory Support Devices
- Histiocytic Disorders and Treatments
- Pluripotent Stem Cells Research
- Diet, Metabolism, and Disease
- Coenzyme Q10 studies and effects
- Metabolism and Genetic Disorders
- Ultrasound in Clinical Applications
- Atrial Fibrillation Management and Outcomes
- Infrared Thermography in Medicine
Meyer Children's Hospital
2018-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2025
Meyer Children's Hospital
2024
University of Florence
2018
Bambino Gesù Children's Hospital
2018
University of Siena
2012-2017
Cardiovascular magnetic resonance (CMR) and computed tomography (CCT) are advanced imaging modalities that recently revolutionized the conventional diagnostic approach to congenital heart diseases (CHD), supporting echocardiography often replacing cardiac catheterization. This is second of two complementary documents, endorsed by experts from Working Group Italian Society Pediatric Cardiology College Cardiac Radiology Medical Interventional Radiology, aimed at giving updated indications on...
Genetic counselling and genetic testing in hypertrophic cardiomyopathy (HCM) represent an integral part of the diagnostic algorithm to confirm diagnosis, distinguish it from phenocopies, suggest tailored therapeutic intervention strategies. Additionally, they enable cascade family. With implementation Next Generation Sequencing technologies (NGS), interpretation data has become more complex. In this regard, cardiologists play a central role, aiding geneticists correctly evaluate...
We report the case of a young woman with Fontan circulation who successfully completed twin pregnancy. The key role multidisciplinary Pregnancy Heart Team for preconception counseling and pregnancy management is emphasized.
Advances in both imaging techniques and genetics have led to the recognition of a wide variety aortic anomalies that can be grouped under term ‘hereditary thoracic diseases’. The present review aims summarize this very heterogeneous population’s clinical, genetic, characteristics discuss implications diagnosis for clinical counselling (on sports activity or pregnancy), medical therapies surgical management.
Background Advancements in cardiac imaging have revolutionized our understanding of ventricular contraction. While ejection fraction (EF) is still the gold standard parameter to assess left ventricle (LV) function, strain (SI) has provided valuable insights into mechanics. The lack an integrative method including SI parameters a single, validated formula may limit its use. Our aim was compare different methods for evaluating global circumferential (GCS) and their relationship with...
Aortic dilation (AoD) is commonly reported in patients with bicuspid aortic valve (BAV) and has been related to flow abnormalities genetic predisposition. AoD-related complications are be extremely rare children. Conversely, an overestimate of AoD body size may lead excess diagnoses negatively impact quality life active lifestyle. In the present study, we compared diagnosis performance newly introduced Q-score (based on a machine-learning algorithm) versus traditional Z-score large...
Background: Managing repaired tetralogy of Fallot (TOF) patients is still challenging despite the fact that published studies identified prognostic clinical or imaging data with rather good negative predictive accuracy but weak positive accuracy. Heterogeneity initial anatomy, surgical approach, and complexity mechanism leading to dilation ventricular dysfunction explain challenge predicting adverse event in this population. Therefore, risk stratification management population remain poorly...
Background: Cardiac involvement is reported in a significant proportion of patients with classical organic acidurias (OAs), contributing to disability and premature death. Different cardiac phenotypes have been described, among which dilated cardiomyopathy (DCM) predominant. Despite recent progress diagnosis treatment, the natural history OAs remains unresolved, specifically regard impact complications. We therefore performed retrospective study address this issue at our Referral Center for...
Restrictive cardiomyopathy (RCM) is characterized by restrictive ventricular pathophysiology determined increased myocardial stiffness. While suspicion of RCM initially raised clinical evaluation and supported electrocardiographic echocardiographic findings, invasive hemodynamic often required for diagnosis management patients during follow-up. commonly associated with a poor prognosis high incidence heart failure, PH reported in paediatric RCM. Currently, only few therapies are available...
The survival of pediatric cancer patients has significantly increased thanks to the improvement oncological treatments. Therefore, it is utmost importance manage short- and long-term cardiovascular complications. In cardio-oncology, there are no recognized guidelines as in adults. Several recommendations many indications have been derived from data obtained adult population, resulting greater discrepancies clinical management patients. aim this position paper Italian Society Pediatric...
Abstract Background The genetic background of paediatric cardiomyopathies is only partially resolved, because their rarity and heterogeneity. However, the assessment aetiology paramount importance in order to define prognosis therapeutic choices. Moreover, recognition causes basis for cascade screening family. Aims This study aimed identify children evaluated followed at our hospital. Methods A validated Next Generation Sequencing (NGS) target panel was performed a cohort 76 patients: 36...