A5021138955- Pregnancy and preeclampsia studies
- Preterm Birth and Chorioamnionitis
- Maternal and fetal healthcare
- Birth, Development, and Health
- Prenatal Screening and Diagnostics
- Reproductive System and Pregnancy
- Pregnancy-related medical research
- Maternal and Perinatal Health Interventions
- Neonatal Respiratory Health Research
- Health and Conflict Studies
- Gestational Diabetes Research and Management
- Ectopic Pregnancy Diagnosis and Management
- Blood Coagulation and Thrombosis Mechanisms
- Pelvic floor disorders treatments
- Cancer Genomics and Diagnostics
- Food Security and Health in Diverse Populations
- Agricultural risk and resilience
- Congenital Diaphragmatic Hernia Studies
- Parvovirus B19 Infection Studies
- Cytomegalovirus and herpesvirus research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Assisted Reproductive Technology and Twin Pregnancy
- Migration, Health and Trauma
- Global Maternal and Child Health
- Endometriosis Research and Treatment
Ben-Gurion University of the Negev
2012-2024
United States Department of Health and Human Services
2018-2020
Wayne State University
2018-2020
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2018-2020
National Institutes of Health
2019-2020
Michigan United
2019
Soroka Medical Center
2013-2015
University Medical Center
2012
Objective To determine the frequency and type of histopathologic lesions in placentas delivered by women with a normal pregnancy outcome. Methods This retrospective cohort study included placental samples from 944 singleton gestation who at term without obstetrical complications. Placental were classified into following four categories as defined Society for Pediatric Pathology our unit: (1) acute inflammation, (2) chronic (3) maternal vascular malperfusion (4) fetal malperfusion. Results...
To identify maternal plasma protein markers for early preeclampsia (delivery <34 weeks of gestation) and to determine whether the prediction performance is affected by disease severity presence placental lesions consistent with vascular malperfusion (MVM) among cases.
ABSTRACT Objective To compare the predictive performance of estimated fetal weight (EFW) percentiles, according to eight growth standards, detect fetuses at risk for adverse perinatal outcome. Methods This was a retrospective cohort study 3437 African‐American women. Population‐based (Hadlock, INTERGROWTH‐21 st , World Health Organization (WHO), Fetal Medicine Foundation (FMF)), ethnicity‐specific (Eunice Kennedy Shriver National Institute Child and Human Development (NICHD)), customized...
To determine whether previously established mRNA signatures are predictive of early preeclampsia when evaluated by maternal cellular transcriptome analysis in samples collected before clinical manifestation.We profiled gene expression at exon-level resolution whole blood longitudinally from 49 women with normal pregnancy (controls) and 13 (delivery <34 weeks gestation). After preprocessing removal gestational age-related trends expression, data were converted into Z-scores based on the mean...
Preeclampsia and fetal growth restriction are obstetrical syndromes associated with abnormal placental implantation changes in the activation status of maternal leukocytes. This study is aimed to determine by a simple, rapid fluorescent assay serum total cell-free DNA (t-cfDNA) concentrations women preeclampsia those (FGR).A cross-sectional was conducted measuring t-cfDNA concentrations. Women were classified into following groups: 1) patients (n = 21); 2) FGR-estimated weight below...
Objectives To investigate mechanisms of in utero death normally formed fetuses by measuring amniotic fluid (AF) biomarkers for hypoxia (erythropoietin [EPO]), myocardial damage (cardiac troponin I [cTnI]) and brain injury (glial fibrillary acidic protein [GFAP]), correlated with risk factors fetal placental histopathology. Methods This retrospective, observational cohort study included intrauterine deaths transabdominal amniocentesis prior to induction labor. Women a normal pregnancy an...
Objectives. Diabetes mellitus (DM) and hypothyroidism are each associated with increased rate of pregnancy complications. However, their combined morbidity during gestation is poorly studied. Therefore, the aims this study were to determine prevalence DM & whether it adverse maternal neonatal outcome. Study design. This population based retrospective cohort included 87,213 women who had 232,293 deliveries. All deliveries divided into following groups: (1) (n = 171); (2) 1502); (3) 13,324);...
Background Nonovert disseminated intravascular coagulation (DIC) is a subclinical hemostatic dysfunction that has not yet reached the decompensation stage. The detection of pregnant patients at this stage may assist in identification those who will develop severe obstetrical hemorrhage, as it one leading causes for preventable maternal mortality. Currently, nonovert DIC diagnosed by scoring system based on nonpregnant patients, originally generated International Society Thrombosis and...
Abstract Background Disseminated Intravascular Coagulation (DIC) is a life-threatening condition. Hemolysis, Elevated Liver enzymes and Low Platelets (HELLP) syndrome one of the obstetrical syndromes mostly associated with DIC thus, high rates fatal complications. There lack information regarding epidemiologic clinical characteristics women who developed HELLP without DIC. Additionally, until now, there no adapted widely accepted way to diagnose among pregnant presenting syndrome, despite...
Recurrent congenital cytomegalovirus infections in consecutive pregnancies are rarely reported. Due to the risk of fetal infection from preconception maternal infection, a 6-month interval after primary is generally advised before new conception. Recently, high-dose valacyclovir treatment was shown prevent first trimester infections. We present case treated with but resulting polymerase chain reaction-confirmed infection. Cytomegalovirus-specific immunoglobulin G titers remained very low...
Objective: In the last few decades, attention has been focused on morbidity and mortality associated with late preterm delivery (34-36 + 6/7 weeks), accounting for 60-70% of all births. This study is aimed to determine (1) prevalence deliveries (spontaneous medically indicated) in our population; (2) rate neonatal as well maternal complications different phenotypes deliveries. Study design: retrospective population-based cohort study, included 96,176 women who had 257,182 deliveries,...
The aim of this study was to evaluate the role cervical length measurement in early third trimester (28-32 weeks) as a predictor preterm delivery (PTD), women presenting with parturition.Cervical measured prospectively, singleton pregnancies at 28-32 weeks contractions (PTC). A multivariate linear regression model performed assess association between and gestational age delivery. Logistic analysis PTD before 34 37 gestation outcome variable control for confounders.Fifty-six were included,...
Cord gas values and Apgar scores, currently used as markers for newborn wellbeing postpartum complications, provide rough estimates, their use remains elusive. Circulating cell-free DNA (cfDNA) may better represent status at birth the effect of parturition on fetus. This pilot study investigates association between cord blood (CB) cfDNA neonatal outcomes.
In summer 2014, southern Israel experienced rocket attacks from the Hamas-ruled Gaza strip on a nearly daily basis for over 50 consecutive days. We exploit this unexpected escalation in Israeli-Palestinian conflict and variation across localities amount of sirens that warned to measure effect intensity birth weight gestation length among mothers who were pregnant during period. addition common notion induces stress anxiety, we also show is correlated with absences work lack prenatal care....
Abstract In summer 2014, southern Israel experienced rocket attacks from the Hamas-ruled Gaza strip on a nearly daily basis for over 50 consecutive days. We exploit this unexpected escalation in Israeli-Palestinian conflict and variation across localities amount of sirens that warned to measure effect intensity birth weight gestation length among pregnant women during period. addition common notion induces stress anxiety, we show changes prenatal care response sirens. This maternal...