A5083779088- Pain Management and Opioid Use
- Pain Mechanisms and Treatments
- Pharmacological Effects and Toxicity Studies
- Palliative Care and End-of-Life Issues
- Health Sciences Research and Education
- Dialysis and Renal Disease Management
- Healthcare professionals’ stress and burnout
- Meta-analysis and systematic reviews
- Healthcare Decision-Making and Restraints
- COVID-19 and Mental Health
- Patient-Provider Communication in Healthcare
- Diet and metabolism studies
- Family Caregiving in Mental Illness
- Organ Donation and Transplantation
- Clinical Reasoning and Diagnostic Skills
- Stress and Burnout Research
- Acute Kidney Injury Research
- Health and Well-being Studies
- Diabetes Management and Research
- Pituitary Gland Disorders and Treatments
- Diabetes Management and Education
- Chronic Disease Management Strategies
- Drug-Induced Hepatotoxicity and Protection
- Cancer Treatment and Pharmacology
- Esophageal and GI Pathology
Kindai University
2016-2024
Osaka Nishi Clinic
2024
Itami City Hospital
2019-2022
Sakai Municipal Hospital
2018-2022
ContextAlthough opioids and pregabalin are widely used for cancer-related neuropathic pain (CNP), no clinical trials exist to determine which medications effective when an opioid-pregabalin combination therapy fails.ObjectivesWe investigated the efficacy of duloxetine CNP nonresponsive or intolerant therapy.MethodsA multicenter, randomized, double-blind, placebo-controlled trial was performed at 12 specialized palliative care services in Japan. Patients with average scores (Brief Pain...
Cancer care is currently the most important medical issue in Japan. Total pain of cancer patients consists a combination four factors: physical, psychological, social distress, and spiritual pain. Previous studies showed female ask for more psychological support seem to suffer different types distress compared with male patients, example, appearance-related symptoms. However, other factors related gender have not been defined comprehensively. The aim this study clarify differences order...
Abstract Background Aspiration pneumonia in older adults is increasingly common, with a high care burden and morbidity. However, clinical competencies its management have not been developed, healthcare professionals struggle on how to for these patients multimodal treatment needs. Therefore, we conducted scoping review investigate what known about the desired of aspiration pneumonia, utilise practice, education, future research. Methods First, defined according preliminary search. We then...
Abstract Background We hypothesized that the high-dose opioid requirement in patients carrying rs4680-GG variant COMT gene encoding catechol-O-methyltransferase would be greater for taking morphine than those oxycodone, thus providing a much-needed biomarker to inform selection cancer pain. Methods A randomized, multicenter, open-label trial was conducted at Japanese hospital’s palliative care service. Patients with pain treated regular doses of nonsteroidal anti-inflammatory drugs or...
Non-organic lesions or diseases of unknown origin are sometimes misdiagnosed as "psychogenic" disorders "psychosomatic" diseases. For the quality life and safety patients, recent attention has focused on diagnostic error. The aim this study was to clarify factors that affected misdiagnoses in psychosomatic medicine by examining typical cases explore strategies reduce errors. period from January 2001 August 2017. data patients who had visited Department Psychosomatic Medicine, Kindai...
Objective To evaluate the change in prevalence of burnout during COVID-19 pandemic among internists and primary care physicians Japan, to identify factors associated with exacerbation these populations this period. Methods This was a cross-sectional study based on two web-based surveys conducted January 2020 (before declaration pandemic) June (during pandemic). The participants were Japanese Chapter American College Physicians. main outcome between before "first wave" pandemic. We also...
There have been few studies on predictive biomarkers that may be useful to select the most suitable opioids optimize therapeutic efficacy in individual patients with cancer pain. We recently investigated of morphine and oxycodone using single nucleotide polymorphisms (SNPs) catechol-O-methyltransferase (COMT) rs4680 gene as a biomarker (RELIEF study). To explore additional enable selection an appropriate opioid for pain, three SNPs were examined: C-C motif chemokine ligand 11 (CCL11;...
The COVID-19 pandemic has affected the mental health of care workers. This study aimed to investigate stress factors that cause burnout in Japanese physicians and their coping methods during pandemic.We conducted a sequential explanatory mixed-method psychological responses early stages pandemic. A cross-sectional, web-based, anonymous survey was among members American College Physicians Japan Chapter quantitatively prevalence burnout. An open-ended questionnaire with questions about...
Carnitine deficiency is reportedly associated with increased pain sensation in diabetes mellitus and fibromyalgia, but the association between serum carnitine concentration cancer has not been fully elucidated. We investigated incidence of patients pain, examined effect patients' demographic clinical characteristics on intensity deficiency. The was measured 50 receiving non‑steroidal anti‑inflammatory drugs, opioids. Multivariate regression analysis used to determine concentration,...
Abstract Background Research engagement contributes to the improvement of patient care. A systematic review is a suitable first scholarly activity because it entails summarization publicly available data and usually requires neither rigorous ethical nor research funding. Methods This study aimed develop model workshop for healthcare staff acquire skills in creating protocols based on their own clinical questions at teaching hospitals. We used an action method create four hospitals Japan from...
Psychonephrology is the field of study encompassing nephrology, psychiatry, and psychosomatic medicine, which based on concept consultation-liaison within biopsychosocial model mind–body unity. The Japanese Society for was founded in Japan 1990 to resolve psychological problems dialysis patients renal transplant patients, whom survival time has increased. Patients with chronic kidney disease (CKD) face various burdens during leading up initiation replacement therapy (RRT) or through...
We have been exploring biomarkers that could help physicians select the appropriate opioid for individualized treatment of cancer pain. Recently, we identified a single nucleotide polymorphism (SNP)