A5007449200- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Traumatic Brain Injury and Neurovascular Disturbances
- Sepsis Diagnosis and Treatment
- Cardiac Structural Anomalies and Repair
- Intensive Care Unit Cognitive Disorders
- Hemodynamic Monitoring and Therapy
- Cardiac, Anesthesia and Surgical Outcomes
- Respiratory Support and Mechanisms
- Neurosurgical Procedures and Complications
- Intracranial Aneurysms: Treatment and Complications
- Acute Myocardial Infarction Research
- Acute Ischemic Stroke Management
- Airway Management and Intubation Techniques
- Electrolyte and hormonal disorders
- Atrial Fibrillation Management and Outcomes
- Tracheal and airway disorders
- Cerebrospinal fluid and hydrocephalus
- Clinical Nutrition and Gastroenterology
- Central Venous Catheters and Hemodialysis
- Bone and Joint Diseases
- Cardiac Ischemia and Reperfusion
- Nutrition and Health in Aging
- Trauma Management and Diagnosis
- Neurological Disorders and Treatments
Samsung Medical Center
2016-2025
Sungkyunkwan University
2016-2025
Extracorporeal cardiopulmonary resuscitation (ECPR) refers to use of extracorporeal membrane oxygenation (ECMO) in arrest. Although ECPR can increase survival rates after cardiac arrest, it also result poor post-resuscitation neurological status. Thus, we investigated predictors good outcomes successful ECPR. A total 227 patients underwent from May 2004 June 2013 at Samsung Medical Center. Successful was defined as more than 24 hours Neurological were assessed discharge using the...
Sepsis is a major cause of mortality and morbidity in critically ill patients. Procalcitonin (PCT) C-reactive protein (CRP) are the most frequently used biomarkers sepsis. We investigated changes PCT CRP concentrations patients with sepsis to determine which biochemical marker better predicts outcome. retrospectively analyzed 171 episodes 157 severe septic shock who were admitted Samsung Medical Center intensive care unit from March 2013 February 2014. The primary endpoint was patient...
The objective of this observational study was to evaluate whether early intervention associated with improved long-term outcomes in critically ill patients cancer.Retrospective analysis prospectively collected data.A university-affiliated, tertiary referral hospital.Consecutive cancer who were managed by a medical emergency team before ICU admission between January 2010 and December 2012.None.During the period, 525 admitted respiratory failure (41.7%) severe sepsis or septic shock (40.6%)...
Limited data are available on imaging predictors of neurological outcomes after extracorporeal cardiopulmonary resuscitation (ECPR). We investigated the association initial brain computed tomography (CT) findings with following ECPR.Between February 2005 and December 2015, a total 42 patients who underwent CT scans within 48 h ECPR were analyzed. Loss boundary between gray matter white (LOB) or cortical sulcal effacement (SE), gray-to-white ratio (GWR), optic nerve sheath diameter (ONSD)...
Background Obesity might be associated with disturbance of cannulation in situation extracorporeal cardiopulmonary resuscitation (ECPR). However, limited data are available on obesity the setting ECPR. Therefore, we investigated association between body mass index (BMI) and clinical outcome patients underwent Methods From January 2004 to December 2013, in-hospital cardiac arrest who had ECPR were enrolled from a single-center registry. We divided into four group according BMI defined WHO...
Background: Current severity scoring systems in intensive care units (ICUs) are complex and time-consuming, limiting their utility for rapid clinical decision-making. This study aimed to develop validate simplified prediction models using readily available biomarkers assessing in-hospital mortality risk. Methods: We analyzed 19,720 adult ICU patients this retrospective study. Three were developed: a basic model lactate-to-albumin ratio (LAR) neutrophil percent-to-albumin (NPAR) two enhanced...
We evaluated the role of optic nerve sheath diameter (ONSD) using brain computed tomography (CT) in predicting neurological outcomes patients with subarachnoid hemorrhage (SAH). This was a retrospective, multicenter, observational study adult SAH admitted between January 2012 and June 2017. Initial CT performed within 12 h from onset SAH, follow-up 24 treatment ruptured aneurysm. Primary outcome status at 6-month assessed Glasgow Outcome Scale (GOS, 1 to 5). Among 223 patients, 202 (90.6%)...
Target temperature management (TTM) and extracorporeal cardiopulmonary resuscitation (ECPR) have been established as important interventions during arrest. However, the impact of combined TTM ECPR on clinical outcomes has not studied in detail.We reviewed records 245 patients who received life support (ECLS) between January 2012 June 2015. Exclusion criteria were follows: Extracorporeal performed for reasons other than cardiac arrest, age less 18 years, death within 24 hours. A total 101...
We evaluated the safety and feasibility of ultrasound-guided peripherally-inserted central venous catheters (PICC) by a neurointensivist at bedside compared to fluoroscopy-guided PICC conventional catheter (CCVC). This was retrospective study adult patients who underwent line placement were admitted neurosurgical intensive care unit (ICU) between January 2014 March 2018. In this study, primary endpoint line-induced complications. The secondary initial success placement. Placements CCVC...
Abstract Background The purpose of this study was to evaluate the role C-reactive protein (CRP) in predicting neurological outcomes patients with subarachnoid hemorrhage (SAH). Methods In retrospective, observational adult SAH treated between January 2012 and June 2017. Initial CRP levels collected within 24 h from onset SAH, follow-up were measured. primary outcome status at six-month assessed Glasgow Outcome Scale (GOS, 1 5). Results Among 156 145 (92.9%) survived until discharge. Of these...
Early proper nutritional support is important to critically ill patients. Nutritional also associated with clinical outcomes of neurocritically We investigate whether early nutrition in This was a retrospective, single-center, observational study including neurosurgical patients who were admitted the intensive care unit (ICU) from January 2013 December 2019. Patients started enteral or parenteral within 72 hours after ICU admission defined as group. The primary endpoint in-hospital...
Intensive Care UnitLimited data are available on improved outcomes after initiation of neurointensivist comanagement in neurosurgical intensive care units (NSICUs) Korea.We evaluated the impact a newly appointed patients admitted to an unit (ICU).This retrospective observational study involved NSICU at Samsung Medical Center between March 2013 and May 2016.Neurointensivist co-management was initiated October 1 2014.We compared before comanagement.The primary outcome ICU mortality.A total 571...
We evaluated the prognostic value of C-reactive protein (CRP), albumin, CRP clearance (CRPc) and CRP/albumin ratio (CAR) in neurocritically ill patients with acute stroke. This is a retrospective, observational study. included stroke who were hospitalized neurosurgical ICU from January 2013 to September 2019. The primary outcome was in-hospital mortality. A total 307 enrolled Among them, 267 (87.0%) survived until discharge hospital. CAR significantly higher non-survivors than survivors...
The objective of this study was to investigate the usefulness fibrinogen-to-albumin ratio (FAR) as a prognostic marker in patients admitted an intensive care unit (ICU) compared with Sequential Organ Failure Assessment (SOFA) score, widely used scoring system. An inverse probability weighting (IPW) control for selection bias and confounding factors. After IPW adjustment, high FAR group showed significantly higher risk 1-year low (36.4% vs. 12.4%, adjust hazard = 1.72; 95% confidence interval...
We investigated the predictors of poor neurological outcomes in extracorporeal cardiopulmonary resuscitation (ECPR) patients using machine learning (ML) approaches.This study was a retrospective, single-center, observational that included adult who underwent ECPR while hospitalized between January 2010 and December 2020. The primary outcome neurologic status at hospital discharge as assessed by Cerebral Performance Categories (CPC) score (scores range from 1 to 5). trained tested eight ML...
We evaluated whether Alberta Stroke Program Early Computed Tomography Score (ASPECTS) with some modifications could be used to predict neurological outcomes in patients after extracorporeal cardiopulmonary resuscitation (ECPR). This was a retrospective, multicenter, observational study of adult unconscious who were by brain computed tomography (CT) within 48 hours ECPR between May 2010 and December 2016. ASPECTS, bilateral ASPECTS (ASPECTS-b), modified (mASPECTS) assessed ROC curves...
D-dimer levels have been used in the diagnosis of a variety thrombosis-related diseases. In this study, we evaluated whether measuring can help to diagnose cerebral infarction (CI) critically ill cancer patients.We retrospectively all patients who underwent brain magnetic resonance imaging (MRI) between March 2010 and February 2014 at medical oncology intensive care unit (ICU) Samsung Medical Center. Brain MRI scanning was performed when CI suspected due acute neurological deficits. We...
It is not rare for a small-bore feeding tube to be inserted incorrectly into the respiratory system in critically ill patients. Thus, monitoring necessary prevent malplacement of tube. We investigated utility capnographic complications due mispositioning patients.This study was pre and post-interventional study, including 445 placements events studied retrospectively medical surgical intensive care units Samsung Medical Center. compared outcomes between time periods before after documented...
We evaluated the optimal mean arterial pressure (MAP) for favorable neurological outcomes in patients who underwent extracorporeal cardiopulmonary resuscitation (ECPR). Adult ECPR were included. The average MAP was obtained during 6, 12, 24, 48, 72, and 96 h after cardiac arrest, respectively. Primary outcome status upon discharge, as assessed by Cerebral Performance Categories (CPC) scale (range from 1 to 5). Overall, with (CPC or 2) tended have a higher than those poor outcomes. Six models...
Our aim is to assess the optimal levels of oxygen and carbon dioxide for prognosis favorable neurologic outcomes in survivors after extracorporeal cardiopulmonary resuscitation (ECPR). We obtained mean PaCO2 PaO2 arterial blood gas samples 72 h ECPR. The primary outcome was neurological status, according Cerebral Performance Categories (CPC) scale, upon discharge. Of 119 (48.6%) survivors, 95 (38.8%) had (CPC 1 or 2). There a U-shaped relationship between tensions poor outcomes. risk lowest...
After a difficult brain tumor surgery, refractory intracranial hypertension (RICH) may occur due to residual or post-operative complications such as hemorrhage, infarction, and aggravated edema. We investigated which predictors are associated with prognosis when using barbiturate coma therapy (BCT) second-tier control RICH after surgery. The study included adult patients who underwent BCT surgery between January 2010 December 2016. primary outcome was neurological status upon hospital...