A5100670569- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- Acute Myocardial Infarction Research
- ZnO doping and properties
- Intensive Care Unit Cognitive Disorders
- Magnetic properties of thin films
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Heart Failure Treatment and Management
- Advanced Bandit Algorithms Research
- Sepsis Diagnosis and Treatment
- Ferroelectric and Piezoelectric Materials
- Stock Market Forecasting Methods
- Gastrointestinal motility and disorders
- Semiconductor materials and devices
- Acoustic Wave Resonator Technologies
- Coronary Interventions and Diagnostics
- Orthopaedic implants and arthroplasty
- Ion channel regulation and function
- Liver Disease Diagnosis and Treatment
- Orthopedic Infections and Treatments
- Cardiovascular Function and Risk Factors
- Anesthesia and Pain Management
- Financial Markets and Investment Strategies
Chung-Ang University Hospital
2023-2025
Konkuk University Medical Center
2012-2025
Chung-Ang University
2022-2024
Sungkyunkwan University
2010-2024
Samsung (South Korea)
2004-2024
Korea Institute of Toxicology
2021-2024
Samsung Medical Center
2023
Soonchunhyang University
2022-2023
Bridge University
2022
Yonsei University
2003-2022
In the current era of mechanical circulatory support, limited data are available on prognosis cardiogenic shock (CS) caused by various diseases. We investigated characteristics and predictors in-hospital mortality in Korean patients with CS.The RESCUE study (Retrospective Prospective Observational Study to Investigate Clinical Outcomes Efficacy Left Ventricular Assist Device for Patients With CS) is a multicenter, retrospective, prospective registry that presented CS. Between January 2014...
Abstract The spread of carbapenem-resistant Enterobacterales (CRE) poses a public health threat worldwide. We aimed to compare the mortality rates between carbapenemase-producing (CP) and non-CP CRE bacteremia. conducted retrospective cohort study in patients with bacteremia after propensity score (PS) matching. performed Kaplan–Meier curve analysis identify cumulative hazard for 30-day mortality. There were 318 January 1, 2018, December 31, 2022. 252 CP-CRE 66 non-CP-RE, respectively....
Giant cell tumor of bone is an aggressive characterized by extensive destruction and high recurrence rates. This consists stromal cells hematopoietic that interact in autocrine manner to produce tumoral osteoclastogenesis resorption. regulation may be disrupted novel therapeutic agents. Nonspecific local adjuvant therapies such as phenol or liquid nitrogen have been used the treatment giant tumor, but specific not described. The bisphosphonates pamidronate Zoledronate can induce apoptosis...
OBJECTIVES: To identify whether the prognostic implications of Vasoactive Inotropic Score according to use mechanical circulatory support differ in treatment acute myocardial infarction complicated by cardiogenic shock. DESIGN: A multicenter retrospective and prospective observational cohort study. SETTING/PATIENT: The REtrospective Study investigate Clinical oUtcomes Efficacy registry includes 1,247 patients with shock from 12 centers Korea. total 836 were finally selected, study population...
Patients with colorectal cancer (CRC) often fail to complete full-course chemotherapy a standard dose due various reasons. This study aimed determine whether body composition affects adherence in patients CRC. The medical records of 107 stage III CRC who underwent adjuvant folinic acid, fluorouracil and oxaliplatin (FOLFOX) at single center between 2014 2018 were analyzed retrospectively. Blood test results for selected immunonutritional markers was measured through computed tomography....
Although culprit-only revascularization during the index procedure has been recommended in patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (CS), reduction residual ischaemia is also emphasized to improve clinical outcomes. However, few data are available about significance of undergoing mechanical circulatory supports. This study aimed evaluate effects on outcomes AMI venoarterial-extracorporeal membrane oxygenation (VA-ECMO). Patients multivessel disease who...
Peristaltic contractions in the stomach are regulated by spread of electrical slow waves from corpus to pylorus. Gastric generated and propagated interstitial cells Cajal (ICC). All regions distal dominant pacemaker area capable generating waves, but orderly gastric peristalsis depends upon a frequency gradient which exceeds antral frequency. Cholinergic, muscarinic stimulation enhances We investigated this phenomenon using intact murine muscles cultured ICC. Acetylcholine (ACh) increased...
Although Alpinia officinarum has been used in traditional medicine for the treatment of several conditions, such as abdominal pain, emesis, diarrhea, impaired renal function, and dysentery, little is known about its function obesity. In this study, we investigated antiobesity effect A. ethanol extract (AOE) on lipid accumulation 3T3-L1 cells obesity mice fed a high-fat diet (HFD). AOE dose-dependently suppressed during differentiation preadipocytes by downregulating CCAAT enhancer binding...
Numerous medicinal plants and their derivatives have been reported to prevent obesity related diseases. Although Syzygium aromaticum has traditionally used as an anodyne, carminative anthelmintic in Asian countries, its potential the prevention treatment of not yet explored. Therefore, present study investigated anti-obesity effect S. ethanol extract (SAE) both vitro vivo. To evaluate SAE vitro, on adipocyte differentiation 3T3-L1 cells was investigated. vivo, mice were assigned three...
Abstract Background Despite the known impact of cardiac function on sepsis outcomes, there is limited understanding how ejection fraction (EF) influences hospital mortality in patients with sepsis-induced cardiomyopathy. This study assesses severity dysfunction determined by echocardiography within first 24 hours diagnosis mortality. Methods In this retrospective cohort study, 2,504 diagnosed and who underwent were analyzed. Based EF, classified into normal (EF ≥ 50%), moderate (30% ≤ EF...
The presence of dedicated intensive care unit (ICU) physicians is associated with reduced ICU mortality. However, the information available on role cardiac intensivists in ICUs (CICUs) limited. Therefore, we investigated association intensivist–directed clinical outcomes adult patients admitted to CICU. In this retrospective study, extracted data from SMART-RESCUE registry, a multicenter, retrospective, and prospective registry presenting cardiogenic shock. Overall, 1,247 CS were enrolled,...
Background Mechanical power (MP) and ventilatory ratio (VR) are crucial metrics in the management of acute respiratory distress syndrome (ARDS). This study aimed to evaluate impact these factors on ICU mortality patients with ARDS undergoing pressure-controlled ventilation. Methods In this retrospective study, we included 600 adult who required mechanical ventilation for > 48 h between March 2018 February 2021 a tertiary referral hospital Korea. The MP was calculated using Becher's...
Beta-phenylethylamine (β-PEA) is a well-known and widespread endogenous neuroactive trace amine found throughout the central nervous system in humans. In this study, we demonstrated effects of β-PEA on psychomotor, rewarding, reinforcing behaviors affective state using open-field test, conditioned place preference (CPP), self-administration, ultrasonic vocalizations (USVs) paradigms. We also investigated role dopamine (DA) D1 receptor behavioral rodents. Using enzyme-linked immunosorbent...
Limited data are available on the mortality rates of patients receiving extracorporeal membrane oxygenation (ECMO) support for coronavirus disease 2019 (COVID-19). We aimed to analyze relationship between COVID-19 and clinical outcomes ECMO.
We have a limited understanding of the effect nonalcoholic fatty liver disease (NAFLD) on development type 2 diabetes.The study subjects included male who had received biennial medical check-ups between 2005 and 2009 been diagnosed with disease. The sustained NAFLD (FL, n=107) non-NAFLD (NFL, n=1,054) were followed to determine diabetes.In FL group, there more impaired fasting glucose (IFG), diabetes high HOMA-IR than in NFL group during 5-year follow-up period (32.7 vs. 17.6%, 1.9 0.3%,...
Dysfunction of the gastrointestinal tract occurs in about 76% patients who are diabetic for more than 10 years. Although diabetes-related dysfunctions stomach such as gastroparesis have been extensively studied over recent years, studies mechanism underlying colonic symptoms long-term diabetes models rare. Therefore, goal our study was to clarify nature dysfunction a rat model.The characteristics smooth muscle were investigated Otsuka Long-Evans Tokushima Fatty (OLETF) rats, an animal model...
Limited data are available on the clinical significance of lactate clearance (LC) in patients with cardiogenic shock (CS). This study investigated prognostic role LC CS patients.We analyzed from 628 RESCUE registry, a multicenter, observational cohort enrolled between January 2014 and December 2018. Univariable logistic regression analysis was performed to determine implications 24 h LC, then were divided into two groups according cut-off value (high [HLC] group vs. low [LLC] group). The...
Previous studies that assessed the risk of cardiovascular outcomes in survivors coronavirus disease 2019 (COVID-19) were likely limited by lack generalizability and selection controls nonrepresentative a counterfactual situation regarding COVID-19-related hospitalization. This study determined whether COVID-19 hospitalization was associated with incident compared to non-COVID-19 pneumonia hospitalization.Nationwide population-based conducted using Korean National Health Insurance Service...
Summary Background: Caudal block is a widely used technique for providing perioperative pain management in children. In this randomized double‐blinded study, we evaluated the effects of preoperative caudal on sevoflurane requirements children with cerebral palsy (CP) undergoing lower limb surgery while bispectral index (BIS) values were maintained between 45 and 55. Methods: 52 Achilles‐tendon lengthening to receive combined general–caudal anesthesia (caudal group, n = 27) or general alone...
Allergen exposure is the most potent factor in allergen sensitization, which affects exacerbation and severity of allergic diseases. Due to industrialization climate change, pattern sensitization has changed over time, incidence diseases also increased. This study investigated status Korean population its effects on
PGE(2) has been linked to the production of gastric arrhythmias such as tachygastria. The interstitial cells Cajal (ICC) generate electrical rhythmicity in gastrointestinal muscles, and may therefore be a target for muscles. We cultured ICC from murine antrum, verified that were Kit immunoreactive, measured spontaneous slow waves. These events caused by inward (pacemaker) currents not blocked nifedipine. Forskolin 8-bromoadenosine 3':5'-cyclic monophosphate (8-Br-cAMP) reduced frequency...