Mihaela Crăescu

ORCID: 0000-0003-1708-3116
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About
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Research Areas
  • Systemic Sclerosis and Related Diseases
  • Nonmelanoma Skin Cancer Studies
  • Inflammatory Myopathies and Dermatomyositis
  • Dermatologic Treatments and Research
  • Skin Diseases and Diabetes
  • Mast cells and histamine
  • Cutaneous Melanoma Detection and Management
  • Hedgehog Signaling Pathway Studies
  • Cutaneous lymphoproliferative disorders research
  • Cancer Diagnosis and Treatment
  • Gastric Cancer Management and Outcomes
  • Skin Protection and Aging
  • Colorectal Cancer Surgical Treatments
  • Cancer and Skin Lesions
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Endometrial and Cervical Cancer Treatments
  • Tumors and Oncological Cases
  • Biomarkers in Disease Mechanisms
  • Uterine Myomas and Treatments
  • Lymphatic System and Diseases
  • Head and Neck Anomalies
  • Dermatological and Skeletal Disorders
  • Psoriasis: Treatment and Pathogenesis
  • melanin and skin pigmentation
  • Sarcoma Diagnosis and Treatment

"Dunarea de Jos" University of Galati
2020-2025

Morpho (United States)
2022-2025

Interface (United States)
2023-2025

Spitalul Clinic de Urgenta Sfantul Ioan
2021-2023

Clinical Emergency Hospital Bucharest
2020-2021

CREST syndrome is a clinical entity associated with systemic sclerosis, which meets at least three of the five features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia. Three these features (Raynaud's sclerodactyly dysmotility) are often present in classical subsets SSc: limited diffuse, their presence association does not define syndrome. Calcinosis seems to be less common SSc its other characteristic Therefore, it can appreciated that calcinosis...

10.2147/jir.s361667 article EN cc-by-nc Journal of Inflammation Research 2022-06-01

The incidence of right colon cancer presented in the stage complications is significant. There are major differences therapeutic approach between elective surgery and emergency surgery. Complications such as hemorrhage, obstruction, perforation require careful evaluation prognostic factors, with morbidity mortality rates being much higher compared to We retrospectively analyzed a group 95 patients admitted County Emergency Hospital St. Apostol Andrei Galati complicated tumors - occlusive,...

10.20944/preprints202501.0991.v1 preprint EN 2025-01-14

<b>Introduction: </b>Skin cancer registers worldwide high morbidity and mortality rates, with costly medical services, its major histopathology subtypes being basal squamous cell carcinoma, melanoma.<br /> <b>Materials method: </b>This 5-year retrospective study included 84 patients admitted to the “Sfântul Apostol Andrei” Emergency Clinical Hospital of Galați in oncology radiotherapy clinic during January 2018-October 2022.<br <b>Results:</b>...

10.29333/ejgm/15994 article EN Electronic Journal of General Medicine 2025-02-18

The incidence of right colon cancer presenting in a stage with complications is significant. There are major differences therapeutic approach between elective surgery and emergency surgery. Complications such as hemorrhage, obstruction, perforation require careful evaluation prognostic factors, morbidity mortality rates being much higher compared to We retrospectively analyzed group 95 patients admitted an the County Emergency Hospital St. Apostol Andrei Galati complicated tumors...

10.3390/life15030350 article EN cc-by Life 2025-02-24

Purpose: Systemic sclerosis (SSc) is a relatively rare collagenosis manifested as microvasculopathy, excessive cutaneous and visceral fibrosis in background of autoimmune alteration. Autoimmune vasculopathy SSc occurs early begins with endothelial cell activation followed by blood vessel intimal proliferation context defective angiogenesis. The alteration peripheral micro macrocirculation evident through vascular lesions, such Raynaud’s phenomenon, telangiectasias, acrocyanosis, digital...

10.2147/ccid.s432422 article EN cc-by-nc Clinical Cosmetic and Investigational Dermatology 2024-01-01

Background and Objectives: Psoriasis is a chronic inflammatory skin disease, biologic therapies have revolutionized treatment by targeting key cytokine pathways. While these effectively control psoriatic lesions, their impact on other cutaneous structures, such as cherry angiomas solar lentigines, remains unclear. Angiomas are benign vascular proliferations influenced systemic inflammation hormonal factors, whereas lentigines UV-induced pigmentary lesions associated with aging sun exposure....

10.3390/medicina61040565 article EN cc-by Medicina 2025-03-22

The scope of the study was to identify associated risk factors lower limb lymphedema development in cervical and endometrial cancer patients. We retrospectively analysed 326 patients: 186 cases (57.06%) with 140 (42.94%) were treated Surgery, Radiotherapy, Oncology Gynaecology Clinics 'St. Apostle Andrew' Emergency Clinical Hospital Galati over 9 years. Adjuvant radiotherapy performed 83.57% cases. chemotherapy 45.16% Over 10 lymph nodes removed 74.73% Incidence 15.05% patients 10% patients,...

10.3892/etm.2020.9311 article EN Experimental and Therapeutic Medicine 2020-10-13

Endometrial stromal sarcoma (ESS) is a rare tumor, predominantly occurring as primary tumor of the uterus. Rare cases extrauterine ESS (EESS) have been reported. Low-grade (LG-ESS) more common than high-grade (HG-ESS). We present five and one case EESS. All received external radiotherapy (EBRT) at Radiotherapy Department Emergency Clinical Hospital 'Sfantul Apostol Andrei' Galati, during 2004-2020. Five underwent EBRT in two-dimensional (2D) technique only patient with three-dimensinal...

10.3892/etm.2021.10891 article EN Experimental and Therapeutic Medicine 2021-10-18

Systemic sclerosis (SSc) is a collagenosis characterized by excessive deposition of collagen in the skin and viscera, background immune disorder. The immunological profile SSc often shows elevated levels antinuclear antibodies (ANAs). However, many authors have identified cases having normal ANA levels, framed as paraneoplastic SSc. Among patients with negative ANAs our group, we did not identify any neoplastic process that could support this hypothesis. extended detection autoantibodies...

10.3892/etm.2021.10426 article EN Experimental and Therapeutic Medicine 2021-07-14

As medical-surgical emergencies, regardless of the causal agent, deep cervical space suppurations are not only a diagnostic challenge, but also therapeutic one. In some cases, in spite proper measures, extremely severe complications can develop. A 5-year retrospective study (2016–2020) was conducted on group 107 patients suffering from suppurations, being hospitalized and treated ENT Clinic “Sf. Apostol Andrei” Emergency County Hospital Galați. This research is clinical-statistical based...

10.3390/life13020535 article EN cc-by Life 2023-02-15

Systemic sclerosis (SSc) is a collagenosis with insufficiently known etiopathogenesis, characterized by microvasculopathy and excessive fibrosis in the context of an autoimmune disorder. The incompletely elucidated pathogenesis limited therapeutic options, disabling aspects, skin lesions pain determine important functional psychological deficiencies which affect quality life. It imperative to observe correlate individual clinical paraclinical data optimize disease management. A group 22...

10.3892/etm.2020.8572 article EN Experimental and Therapeutic Medicine 2020-02-27

Psoriasis is a systemic inflammatory cutaneous disease that affects approximately 2% of the world's population. Systemic treatments and biologic treatment therapies are powerful option for patients with moderate to severe psoriasis. Some studies from literature indicate an overall small, but increased, risk neoplasia in psoriasis treated phototherapy or medication. The relationship between malignancy not very well established; there few conflicting results. We present case 31-year-old male...

10.3892/etm.2021.10789 article EN Experimental and Therapeutic Medicine 2021-09-23

Background: This study aims to explore the tumor-stroma separation or cleft characterizing basal cell carcinoma (BCC). Methodology: In this retrospective cohort investigation, we enrolled 244 patients who received a confirmed diagnosis of BCC through histopathological examination in period 2019-2020 at Pathology Laboratory "Sfântul Apostol Andrei" Emergency Clinical Hospital located Galați, Romania. The identification was accomplished by utilizing electronic health records, and relevant...

10.7759/cureus.71244 article EN Cureus 2024-10-11

COVID-19 pandemic represents a challenge for entire medical world, with profound implications in daily practice, making compromise between risk of infection SARS-COV2 and oncological treatment continuing, conditions which must be balanced, each patient, the COVID-19.We are presenting recommendations professional societies actions take Radiotherapy Department "Sf.Ap.Andrei" Emergency Clinical Hospital, Galati order to limit spread concomitant radiotherapy performing, without compromising quality act.

10.31689/rmm.2020.27.2.97 article EN cc-by Medicina Moderna - Modern Medicine 2020-06-26

Systemic sclerosis (SSc) is a relatively rare autoimmune disease with skin and visceral involvement, having yet unknown etiopathogenesis. Research has shown that professional exposure to various polluting chemicals such as dyes, aliphatic aromatic organic solvents, inhalable silica dust or certain heavy metals, can be triggering factors for this when they overlap predisposing genetic profile. Smoking still debated factor involved in the etiology of SSc, authors have divergent opinions on...

10.3892/etm.2020.9511 article EN Experimental and Therapeutic Medicine 2020-11-26

Systemic sclerosis (SSc) is a collagenosis, in which the microvasculature of skin and internal organs becomes affected, followed by excessive deposition connective tissue. It has been included group rare diseases, it seems to have had an increasing incidence over last two decades. Statistics show, not only increase SSc, but that autoimmune diseases as whole. The present study aimed outline epidemiological profile SSc southeast region Romania identify similarities differences concerning...

10.3892/etm.2020.9509 article EN Experimental and Therapeutic Medicine 2020-11-26
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