A5102871920- Breast Cancer Treatment Studies
- Breast Lesions and Carcinomas
- Metastasis and carcinoma case studies
- Cancer Treatment and Pharmacology
- Breast Implant and Reconstruction
- Drug Transport and Resistance Mechanisms
- Cancer and Skin Lesions
- Gastrointestinal Tumor Research and Treatment
- Gastric Cancer Management and Outcomes
- Sarcoma Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Advanced Breast Cancer Therapies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Vascular Tumors and Angiosarcomas
- Cancer-related Molecular Pathways
- Reconstructive Surgery and Microvascular Techniques
- Pleural and Pulmonary Diseases
- Neuroendocrine Tumor Research Advances
- Estrogen and related hormone effects
- Gastrointestinal disorders and treatments
- Cancer Risks and Factors
- Vagus Nerve Stimulation Research
- Thyroid and Parathyroid Surgery
- Head and Neck Anomalies
Amerikan Hastanesi
2021
Acıbadem University
2017-2018
Memorial Ankara Hospital
2005-2017
Liv Hospital
2017
Bursa Uludağ Üni̇versi̇tesi̇
2017
Istanbul University
2017
Marmara University
2017
Pamukkale University
2017
Ministry of Health
2015
Turkish Society of Cardiology
2013
Abstract Introduction: Previous reports of carefully selected patients presenting with stage IV breast cancer (BC) suggest that surgery on the primary tumor may result in improved survival, but this remains unproven. The MF07-01 trial is a phase III randomized controlled BC women distant metastases at presentation who receive loco-regional (LR) treatment for intact compared those do not such treatment. Aim: objective to compare overall survival (OS) treated or without initial LR resection...
Background: Advanced breast cancer cases can still be encountered resulting in poor prognosis. The primary treatment for these patients is chemotherapy, and multidrug resistance (MDR) a serious obstacle the treatment. Detecting drug before first-line chemotherapy may increase patient’s survival. In this study, role of MDR evaluated locally advanced patients. Methods: Reverse transcriptase polymerase chain reaction was used detection genes, ABCB1 ABCC1. Immunohistochemistry proteins,...
Abstract: Local recurrence is an issue of concern after breast-conserving therapy and removing the primary tumor with negative surgical margins most important determinant local recurrence. However, some patients positive initial surgery will have no residual in re-excision specimen. To avoid unnecessary re-excisions, factors predicting disease material should be determined. This study aimed to determine predictive for a homogeneous group only invasive ductal carcinoma. Breast cancer treated...
The diagnosis and management of phyllodes tumors is challenging due to its low incidence. treatment these surgery, however the extent application adjuvant chemotherapy radiotherapy are still controversial. Therefore, we aimed evaluate patients who were treated with a tumor breast in our clinic.Patients between June 2011 2013 reviewed retrospectively. Patient demographic characteristics (age, gender), menopausal status, symptoms, radiologic surgical methods used for treatment, histopathologic...
We compared the efficacy of topical nitroglycerin and transcutaneous electrical nerve stimulation (TENS) on survival random-pattern skin flaps in rats. Thirty Wistar albino rats were used a dorsal, cranially-based flap was raised. The divided into three groups 10 each. first group had only raised while second third given 5 mg or TENS for one hour day seven days. amount necrosis measured seventh postoperative day. mean area 726.2, 544.2, 150.0 mm 2 control, nitroglycerin, groups,...
Multidrug resistance (MDR) is a serious handicap towards the effective treatment of breast cancer patients. One most prevalent MDR mechanisms through overexpression genes coding proteins called Resistance-associated Proteins (MRPs). The aim this study was to investigate expression MRP1 in tumor tissues from In study, semi-quantitative RT-PCR approach utilized. Our results suggest that can mediate Pre-evaluation level such mediators before chemotherapy increase efficacy treatment.
AbstractDrug resistance to chemotherapy in patients with locally advanced breast cancer results a decrease treatment efficacy and patient survival. This study aimed evaluate the impact of ABCB1 ABCC1 gene induction during on disease-free overall survival patients.Patients were prospectively included. All preoperatively treated underwent mastectomy. protein expressions evaluated both before after investigated as molecular predictive parameters affecting disease free RTPCR following RNA...
Aims: Presence of a relationship between autoimmunity and malignant diseases has been investigated for long time. Anti-SS-B anti-centromere protein (CENP)-B antibodies are used as serologic markers autoimmune diseases. In this study, these autoantibodies were studied in breast cancer patients, their effect on survival was evaluated. Patients & methods: Breast patients treated January June 2003 prospectively included study. Antibodies by ELISA, serum values greater than 10 U/ml accepted...
Post-laparotomy wound dehiscence, evantration and evisceration are important complications leading to an increase in both morbidity mortality. Incisional hernias frequently observed following abdominal surgeries their occurrence is related various local systemic factors. This study aims analyze the factors affecting healing by investigating parameters that may cause incisional hernia, sinus formation chronic pain.The records of 265 patients who underwent major surgery were analyzed. The data...
Meigs syndrome is defined as the triad of benign ovarian tumor with ascites and pleural effusion that resolve after resection tumor. Pseudomeigs' a serious disease characterized by malignant tumor, but hydrothorax usually reveal no cells. Here, we report 47-year-old pre-menapausal female patient cardia cancer. Nearly 14 months D3 dissection, she developed Krukenberg tumors on both ovaries causing right hydrothorax, which resolved dramatically rectouterine pouch peritonectomy. She survived...
Aims and background.The aim of the study was to determine incidence venous thrombosis in cancer patients with central catheters inserted perioperatively. Methods design.A prospective analysis performed 68 whom were placed Cancer planned had prophylaxis low-molecular-weight heparin. Patient characteristics, procedure-related complications related recorded. In order detect thrombosis, color Doppler sonography used after removal catheter. Results. The median age 55 years (range, 24-83)....
As the awareness of society on breast cancer and screening for increased, more patients with early were diagnosed. Attempts to preserve healthy tissue acceptable oncological cosmetic outcomes became a challenge surgeon. result, conserving therapy (BCT) has evolved fundamentally changed management cancer.
Gastric cancer is often diagnosed at an advanced stage and surgery alone cannot guarantee satisfactory results. Both chemoradiotherapy (CRT) chemotherapy (CT) are used in postoperative therapy. However, it controversial whether CRT or CT better after D2 lymphadenectomy. In this study we investigated the efficacy of adjuvant versus III gastric patients treated with R0 gastrectomy lymph node dissection.Data from 92 adenocarcinoma followed by treatment were retrospectively analyzed. Patients...