A5056711512- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Clinical practice guidelines implementation
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Peripheral Artery Disease Management
- Health Systems, Economic Evaluations, Quality of Life
- Traumatic Brain Injury and Neurovascular Disturbances
- Trauma and Emergency Care Studies
- Intracranial Aneurysms: Treatment and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Emergency and Acute Care Studies
- Climate Change and Health Impacts
- COVID-19 and healthcare impacts
- Machine Learning in Healthcare
- Healthcare Policy and Management
- Artificial Intelligence in Healthcare and Education
- Influenza Virus Research Studies
- Acute Myocardial Infarction Research
- Cardiac Health and Mental Health
- Healthcare cost, quality, practices
- vaccines and immunoinformatics approaches
- Heparin-Induced Thrombocytopenia and Thrombosis
University of Calgary
2015-2025
Alberta Children's Hospital
2016-2025
Libin Cardiovascular Institute of Alberta
2025
Alberta Children's Hospital Research Institute
2025
Foothills Medical Centre
2013-2024
Deleted Institution
2023
University of Alberta
2016-2022
Alberta Health
2016-2022
Alberta Health Services
2017-2022
Allen Institute for Brain Science
2022
Ischemic stroke with large-vessel occlusion can be treated alteplase and/or endovascular therapy; however, the administration of each treatment is time sensitive.To identify optimal triage and transport strategy: direct to center (mothership) or immediate followed by transfer (drip ship), for all patients suspected stroke.This was a theoretical, conditional probability modeling study. Existing data from clinical trials were used model generation. The study conducted February 1, 2017, March...
Background and Purpose— There is uncertainty regarding the best way for patients outside of endovascular-capable or Comprehensive Stroke Centers (CSC) to access endovascular treatment acute ischemic stroke. The role nonendovascular-capable Primary (PSC) that can offer thrombolysis with alteplase but not unclear. A key question whether average benefit greater early at closest PSC before transportation CSC (Drip ‘n Ship) bypass direct transport (Mothership). Ideal options were mapped based on...
To determine whether active negative pressure peritoneal therapy with the ABThera temporary abdominal closure device reduces systemic inflammation after abbreviated laparotomy.Excessive injury or intra-abdominal sepsis is associated poor outcomes.We conducted a single-center, randomized controlled trial. Forty-five adults (46.7%) (52.3%) were randomly allocated to (n = 23) Barker's vacuum pack 22). On study days 1, 2, 3, 7, and 28, blood fluid collected. The primary endpoint was difference...
To evaluate whether the use of multiphase CT angiography (CTA) improves interrater agreement for intracranial occlusion detection between stroke neurology trainees and an expert neuroradiologist.A neuroradiologist 2 fellows independently reviewed 100 prospectively collected single-phase CTA scans from acute ischemic patients with mild symptoms (NIH Stroke Scale score ≤5). The presence location a vascular occlusion(s) were documented. Interrater single- was quantified using unweighted κ...
The effectiveness of specific systems changes to reduce DTN (door-to-needle) time has not been fully evaluated. We analyzed the impact 4 reduction strategies implemented prospectively in a staggered fashion.The HASTE (Hurry Acute Stroke Treatment and Evaluation) project was 3 phases at single academic medical center. In I (June 6, 2012 June 5, 2013), baseline performance analyzed. II 2013 January 24, 2015), were implemented: (1) STAT stroke protocol prenotify team about incoming patients;...
Introduction In ischaemic stroke care, fast reperfusion is essential for disability free survival. It unknown if bypassing thrombolysis centres in favour of endovascular thrombectomy (mothership) outweighs transport to the nearest centre alteplase and then transfer (drip-and-ship). We use conditional probability modelling determine impact treatment times on decision-making acute stroke. Materials methods Probability good outcome was modelled using a previously published framework, data from...
Respiratory infection can be an immediate precursor to stroke and myocardial infarction. Influenza vaccination is associated with reduced risk of infarction hospitalisation for cardiac disease, influenza strongly recommended patients heart disease. Evidence on whether the same protective association exists stroke, this potential effect consistent across age groups, conflicting. We aimed assess after in adults.We obtained administrative data from Alberta Health Care Insurance Plan (which...
Pandemics may promote hospital avoidance, and added precautions exacerbate treatment delays for medical emergencies such as stroke. We sought to evaluate ischemic stroke presentations, management outcomes during the first year of COVID-19 pandemic.We conducted a population-based study, using linked administrative registry data from Alberta identify all patients presenting with before pandemic (Jan. 1, 2016 Feb. 27, 2020) in 5 periods over (Feb. 28, 2020 Mar. 31, 2021), reflecting changes...
Artificial intelligence (AI) deployed into healthcare settings is touted as an exciting approach for improving health equity. However, several issues need to be addressed before this could achieved, including the collection and use of social determinants data, enhancing data interoperability, closing digital divide conducting rigorous assessment evaluation AI applications ensure that they achieve fair equitable outcomes in real-world settings. Importantly, we should not neglect...