A5052629826- Yersinia bacterium, plague, ectoparasites research
- Pharmacological Effects of Natural Compounds
- Salmonella and Campylobacter epidemiology
- Clostridium difficile and Clostridium perfringens research
- Aquaculture disease management and microbiota
- Listeria monocytogenes in Food Safety
- Antibiotic Resistance in Bacteria
- Microbial infections and disease research
- Food Safety and Hygiene
- Probiotics and Fermented Foods
- Pneumonia and Respiratory Infections
- Muscle activation and electromyography studies
- Bacteriophages and microbial interactions
- Sports Dynamics and Biomechanics
- Gaze Tracking and Assistive Technology
- Tactile and Sensory Interactions
- Drug Transport and Resistance Mechanisms
- Mathematical Dynamics and Fractals
- Sports Performance and Training
- Animal Nutrition and Physiology
- Plant-based Medicinal Research
- Streptococcal Infections and Treatments
- Human-Animal Interaction Studies
- Trace Elements in Health
- Head and Neck Surgical Oncology
Liverpool John Moores University
2024
Fuji University
2004-2022
RIKEN Center for Biosystems Dynamics Research
2019-2022
Tokyo University of Agriculture and Technology
1994-2021
The University of Tokyo
1984-2018
Osaka City University
2018
RIKEN
1995-2018
Nagasaki University
2014-2016
Tokyo City University
2012
Toshiba (Japan)
2012
Various positron emission tomography (PET) probes have been developed to assess in vivo activities humans of drug transporters, which aid the prediction pharmacokinetic properties drugs and impact drug-drug interactions. We a new PET probe, sodium (3<i>R</i>, 5<i>R</i>)-3, 5-dihydroxy-7-((1<i>S,</i> 2<i>S</i>, 6<i>S</i>, 8<i>S</i>)-6-hydroxy-2-methyl-8- ((1-[<sup>11</sup>C]-(<i>E</i>)-2-methyl-but-2-enoyl) oxy) -1, 2, 6, 7, 8, 8<i>a</i>-hexahydronaphthalen-1-yl) heptanoate...
Two features of the instability torus along amplitude direction are investigated, using various two-dimensional mappings. First, oscillation a in delayed logistic map is studied, which related with an unstable manifold periodic saddle. The also analyzed from another point view, i.e., synergetic effect rotation, stretching and folding, typically seen piecewise-linear mapping. Critical phenomena after onset chaos discussed. Second, doubling reinvestigated. A occurs only finite number times....
To determine the phage types (PT) of Salmonella enteritidis found in Thailand and to clarify potential for human infection by S. broiler chicken meat, poultry isolates taken from between 1990 1997 were typed analyzed pulsed-field gel electrophoresis (PFGE). Ten different PT among 302 typed, with 4 being most frequent (73.9%) (76.2%) isolates, followed 1 (8.0%), 8 (3.6%), 7a (2.2%) (4.9%), (3.7%), 12 (2.4%) isolates. Of 53 PFGE, 45 showed an indistinguishable pattern (pattern A) BlnI-digested...
ABSTRACT AmpC regulatory genes in 21 ceftazidime-resistant clinical isolates of Enterobacter cloacae (MICs ≥16 μg/ml) were characterized. All exhibited overproduction due to AmpD mutation. Additionally, we found two AmpR mutants among the isolates. This is first report chromosomal ampR mutation E. .
Streptococcus pneumoniae is an important human pathogen. Currently used conjugate vaccines are effective against invasive disease, but protection restricted to serotypes included in the formulation, leading serotype replacement. Furthermore, non-invasive disease reported be considerably lower. The development of a serotype-independent vaccine thus and Pneumococcal surface protein A (PspA) promising candidate. PspA shows some diversity can classified 6 clades 3 families, with families 1 2...
Effect of different types in-mold electromagnetic brake (EMBr) technique, which forms a local magnetic field and level in the width direction mold, on fluid flow phenomena strand pool was examined. A mercury model experiment revealed that developed plug-like pool, could not be obtained by field. Surface velocity near meniscus stably controlled with field, while case this surface greatly affected nozzle condition. Numerical analysis clarified characteristics distribution an induced electric...
Cecal contents of 2, 345 broiler chickens consisting 28 flocks originated from 12 farms were examined for the prevalence Salmonella to know actual status infection with in chicken flocks. was isolated 336 (14.3%) samples. From these isolates, eight serovars identified. Of 242 (72.0%) serotyped as S. Blockley, 60 (17.9%) Hadar, 15 (4.5%) Bredeney, nine (2.7%) Schwarzengrund, four (1.2%) Anatum, three (0.9%) Enteritidis, two (0.6%) Ohio, and one (0.3%) Livingstone. The same repeatedly found...
ABSTRACT A clinical isolate of Escherichia coli from a patient in Japan, KU6400, was found to produce plasmid-encoded β-lactamase that conferred resistance extended-spectrum cephalosporins and cephamycins. Resistance arising production could be transferred by either conjugation or transformation with plasmid pKU601 into E. ML4947. The substrate inhibition profiles this enzyme resembled those the AmpC β-lactamase. gene pKU601, which cloned expressed , proved contain an open reading frame...
The development of intestinal Lactobacillus spp. in 18 normal piglets from six litters was investigated 1 to 45 d after birth. Faecal strains isolated and their dams were identified at species biovar levels on the basis carbohydrate fermentation. A definite pattern observed changes four 20 biovars lactobacilli appearing faeces, with growth piglets. reuteri colonized animals first day Lact. acidophilus group appeared week birth maintained high intestine. Biovars B, C E recovered as major...
Campylobacter jejuni was isolated from 44 of 313 free-living birds Japan. The highest isolation rate found in 30 87 (34%) crows (Corvus levaillanti and Corvus corone), followed by 2 10 (20%) blue magpies (Cyanopica cyanus), 5 35 (14%) gray starlings (Sturnus cineraceus), 16 (13%) domestic pigeons (Columbia livia domestica), 4 36 (11%) bulbuls (Hypsipetes amaurotis), 1 62 (2%) eastern turtledoves (Streptopelia orientalis). One-fourth the contents crop stomach human refuse. One-third consisted...
The basin structure of a class one-dimensional mappings is studied. In model proposed by the present authors, attraction separated into uncountable pieces open intervals and has kind self-similarity. Symbolic sequences are used to elucidate structure. way breakdown due noise studied on basis analysis using symbolic sequences. effect crisis discussed.
Yersinia species were isolated from 16 of 495 small wild animals and 1 38 foxes. The trapped in seven regions Hokkaido, Japan. Of the 17 strains isolated, 9 enterocolitica O6; 2 Y. O5A; was enterocolitica, O4; O9; pseudotuberculosis IVB; 3 sucrose-negative strains. pestis not isolated. O6 organism most prevalent large red-back mice (Clethrionomys rufocanus bedfordiae) showed significant differences its mode distribution according to region. Incidence ileum animal threefold that cecum,...
In November 1992 and June August 1993 rectal contents from 204 small mammals living in the wild were collected examined for presence of Yersinia enterocolitica serovar O:8 to clarify source human infections caused by this microbe Tsugaru Region Aomori Prefecture, Japan. Serovar was isolated 10 (5.2%) 193 rodents trapped (9 107) (1 23) but not animals (0 63). This 11 moles. From May September 1993, 12 patients found have become ill be infected with Y. O:8. The lived same districts where...
From July 1976 to May 1977, 270 rats (259 Rattus norvegicus and R. rattus) in Sapporo were examined for the presence of Yersinia enterocolitica house rats. The organism was isolated 55 (54 1 rattus). Isolated strains determined as O group (O)3, biovar 4; O4, 1; O5A, O6, 1. isolation O3, 4 from is first world, far we know. duodenum 3 rats, jejunum 7 ileum 8 cecum 34 colon 23 rectum 16 mesenteric lymph nodes 5 not liver, spleen, kidneys. Isolation made out 2 O3-positive O5A-positive ones, 29...
Yersinia pseudotuberculosis was isolated from 8 (8 Rattus norvegicus) of 270 (259 R. norvegicus and 11 rattus) rats examined. Seasonal variation not found in the incidence isolations. The isolation occurred almost equally both young old rats. strains were determined as serovar IB one rat, IVA seven contents intestinal tract (the duodenum, jejunum, ileum, cecum, colon, rectum), spleen, liver mesenteric lymph nodes; they detected kidneys. Agglutinin titer eight no more than 32.
Visual fatigue caused by prolonged work viewing a Display Terminals (VDT) and of reading hard-copy were assessed electromyogram (EMG) waveform electrooculogram (EOG) in spontaneous blinks as objective criteria, questionnaire subjective feeling, task performance. The duration the amplitude EMG orbicularis ocular muscle on right side EOG vertical direction to eyelid measured for 10 subjects who participated figure consisting addition single-digit numbers VDT or with hard-copy. mean values...
From December 1994 to February 1995, 131 wild boars (Sus scrofa leucomysta) living in a mountainous area Japan were examined for yersiniosis and listeriosis. Of boars, 76 (58%) males 55 (42%) females. Four Yersiniaspp. including Y. pseudotuberculosis, enterocolitica, frederiksenii,and aldovei,were isolated from 49 (37%) of boars. Yersinia pseudotuberculosiswas five (4%) All pseudotuberculosisisolates serotype 4b harbored virulence plasmids. only under 2-yr-old. No human pathogenic...
For a certain class of two-dimensional mappings, torus oscillates more and strongly as the bifurcation parameter is increased. It becomes fractal at critical point chaos appears above point. The discovery this phenomenon, calculation dimension, universality phenomenon are reported.