Analyse T. Roberts

ORCID: 0000-0003-1766-0147
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About
Contact & Profiles
Research Areas
  • Neurotransmitter Receptor Influence on Behavior
  • Stress Responses and Cortisol
  • Mental Health Research Topics
  • Peroxisome Proliferator-Activated Receptors
  • Neuropeptides and Animal Physiology
  • Regulation of Appetite and Obesity
  • Adipose Tissue and Metabolism
  • Alcohol Consumption and Health Effects
  • Hormonal and reproductive studies
  • Pain Mechanisms and Treatments
  • Receptor Mechanisms and Signaling

Università di Camerino
2024-2025

Medical University of South Carolina
2021-2025

University of California, San Diego
2024-2025

Jacksonville State University
2025

Wake Forest University
2025

The Ohio State University
2024

The behavioral and diagnostic heterogeneity within the opioid use disorder (OUD) diagnosis is not readily captured in current animal models, limiting translational relevance of mechanistic research that conducted experimental animals. authors hypothesized a nonlinear clustering OUD-like traits would capture population yield subpopulations OUD vulnerable rats with distinct neurocircuit profiles. Over 900 male female heterogeneous stock rats, line capturing genetic present humans, were...

10.1176/appi.ajp.20230623 article EN American Journal of Psychiatry 2025-01-15

Abstract The increased prevalence of opioid use disorder (OUD) makes it imperative to disentangle the biological mechanisms contributing individual differences in OUD vulnerability. shows strong heritability, however genetic variants vulnerability remain poorly defined. We performed a genome-wide association study using over 850 male and female heterogeneous stock (HS) rats identify genes underlying behaviors associated with such as nociception, well heroin-taking, extinction seeking...

10.1038/s41380-025-02922-4 article EN cc-by Molecular Psychiatry 2025-02-25

The behavioral and diagnostic heterogeneity within human opioid use disorder (OUD) diagnosis is not readily captured in current animal models, limiting translational relevance of the mechanistic research that conducted experimental animals. We hypothesize a non-linear clustering OUD-like traits will capture population yield subpopulations OUD vulnerable rats with distinct neurocircuit profiles.

10.1101/2024.02.22.581440 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-02-23

Opioid use disorder is a psychological condition that affects over 200,000 people per year in the U.S., causing Centers for Disease Control and Prevention to label crisis as rapidly spreading public health epidemic. The behavioral relationship between opioid exposure development of (OUD) varies greatly individuals, implying existence sup-populations with varying degrees vulnerability. However, effective pre-clinical identification these sub-populations remains challenging due complex...

10.3389/fpsyt.2021.745468 article EN cc-by Frontiers in Psychiatry 2021-12-17

Abstract The increased prevalence of opioid use disorder (OUD) makes it imperative to disentangle the biological mechanisms contributing individual differences in OUD vulnerability. shows strong heritability, however genetic variants vulnerability remain poorly defined. We performed a genome-wide association study using over 850 male and female heterogeneous stock (HS) rats identify genes underlying behaviors associated with such as nociception, well heroin-taking, extinction seeking...

10.1101/2024.02.27.582340 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-02-29

<title>Abstract</title> The increased prevalence of opioid use disorder (OUD) makes it imperative to disentangle the biological mechanisms contributing individual differences in OUD vulnerability. shows strong heritability, however genetic variants toward vulnerability remain poorly defined. We performed a genome-wide association study using over 850 male and female heterogeneous stock (HS) rats identify genes underlying behaviors associated with such as nociception, well heroin-taking,...

10.21203/rs.3.rs-4637892/v1 preprint EN cc-by Research Square (Research Square) 2024-08-22

Abstract Opioid use disorder is a psychological condition that affects over 200,000 people per year in the U.S., causing Centers for Disease Control and Prevention to label crisis as rapidly spreading public health epidemic. It has been found behavioral relationship between opioid exposure development of varies greatly individuals, implying existence sup-populations with varying degrees vulnerability. In this study, we assessed several variables across heroin taking, refraining seeking...

10.1101/2021.06.30.450568 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-07-01
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