A5007818112- Neurotransmitter Receptor Influence on Behavior
- Stress Responses and Cortisol
- Mental Health Research Topics
- Peroxisome Proliferator-Activated Receptors
- Neuropeptides and Animal Physiology
- Regulation of Appetite and Obesity
- Adipose Tissue and Metabolism
- Alcohol Consumption and Health Effects
- Hormonal and reproductive studies
- Pain Mechanisms and Treatments
- Receptor Mechanisms and Signaling
Università di Camerino
2024-2025
Medical University of South Carolina
2021-2025
University of California, San Diego
2024-2025
Jacksonville State University
2025
Wake Forest University
2025
The Ohio State University
2024
The behavioral and diagnostic heterogeneity within the opioid use disorder (OUD) diagnosis is not readily captured in current animal models, limiting translational relevance of mechanistic research that conducted experimental animals. authors hypothesized a nonlinear clustering OUD-like traits would capture population yield subpopulations OUD vulnerable rats with distinct neurocircuit profiles. Over 900 male female heterogeneous stock rats, line capturing genetic present humans, were...
Abstract The increased prevalence of opioid use disorder (OUD) makes it imperative to disentangle the biological mechanisms contributing individual differences in OUD vulnerability. shows strong heritability, however genetic variants vulnerability remain poorly defined. We performed a genome-wide association study using over 850 male and female heterogeneous stock (HS) rats identify genes underlying behaviors associated with such as nociception, well heroin-taking, extinction seeking...
The behavioral and diagnostic heterogeneity within human opioid use disorder (OUD) diagnosis is not readily captured in current animal models, limiting translational relevance of the mechanistic research that conducted experimental animals. We hypothesize a non-linear clustering OUD-like traits will capture population yield subpopulations OUD vulnerable rats with distinct neurocircuit profiles.
Opioid use disorder is a psychological condition that affects over 200,000 people per year in the U.S., causing Centers for Disease Control and Prevention to label crisis as rapidly spreading public health epidemic. The behavioral relationship between opioid exposure development of (OUD) varies greatly individuals, implying existence sup-populations with varying degrees vulnerability. However, effective pre-clinical identification these sub-populations remains challenging due complex...
Abstract The increased prevalence of opioid use disorder (OUD) makes it imperative to disentangle the biological mechanisms contributing individual differences in OUD vulnerability. shows strong heritability, however genetic variants vulnerability remain poorly defined. We performed a genome-wide association study using over 850 male and female heterogeneous stock (HS) rats identify genes underlying behaviors associated with such as nociception, well heroin-taking, extinction seeking...
<title>Abstract</title> The increased prevalence of opioid use disorder (OUD) makes it imperative to disentangle the biological mechanisms contributing individual differences in OUD vulnerability. shows strong heritability, however genetic variants toward vulnerability remain poorly defined. We performed a genome-wide association study using over 850 male and female heterogeneous stock (HS) rats identify genes underlying behaviors associated with such as nociception, well heroin-taking,...
Abstract Opioid use disorder is a psychological condition that affects over 200,000 people per year in the U.S., causing Centers for Disease Control and Prevention to label crisis as rapidly spreading public health epidemic. It has been found behavioral relationship between opioid exposure development of varies greatly individuals, implying existence sup-populations with varying degrees vulnerability. In this study, we assessed several variables across heroin taking, refraining seeking...