A5074484583- Vibrio bacteria research studies
- Bacterial Infections and Vaccines
- Salmonella and Campylobacter epidemiology
- Escherichia coli research studies
- Microbial infections and disease research
- Bacteriophages and microbial interactions
- Animal Virus Infections Studies
- Streptococcal Infections and Treatments
- Bacterial Identification and Susceptibility Testing
- Biosensors and Analytical Detection
- Surgical Sutures and Adhesives
- Hemostasis and retained surgical items
- Electrospun Nanofibers in Biomedical Applications
- Antibiotic Resistance in Bacteria
- Aquaculture disease management and microbiota
- Neonatal and Maternal Infections
East China Normal University
2025
Yangzhou University
2021-2024
Kunming University of Science and Technology
2019-2022
University of Florida
2021
Second People's Hospital of Yunnan Province
2019
The Tol-Pal system of Gram-negative bacteria is necessary for maintaining outer membrane integrity. It a multiprotein complex five envelope proteins, TolQ, TolR, TolA, TolB, and Pal. These proteins were first investigated in E. coli, subsequently been identified many other bacterial genera. However, the function Salmonella Choleraesuis pathogenesis still unclear. Here, we reported role three these phenotype biology S. Choleraesuis. We found that mutations tolA, tolB, tolR caused severe...
Bacterial outer membrane vesicles (OMVs) are considered a promising vaccine platform for their high built-in adjuvanticity and ability to efficiently induce immune responses. OMVs can be engineered with heterologous antigens based on genetic engineering strategies. However, several critical issues should still validated, including optimal exposure the OMV surface, increased production of foreign antigens, nontoxicity, induction powerful protection. In this study, lipoprotein transport...
Abstract Clay‐based hemostatic materials are commercially available devices designed to control massive bleeding. However, their widespread application is hindered by concerns related material safety and efficacy. In this study, a aerogel composed of cellulose nanofibers (CNFs) Calcium ion‐exchanged nanoporous zeolite developed. CNFs facilitate the in‐situ synthesis zeolites, zeolites firmly embedded within through abundant hydrogen bonds. Notably, loading in only 2.89 wt.%, significantly...
Mycoplasma hyopneumoniae (M. hyopneumoniae, Mhp) is the etiological agent of swine enzootic pneumonia (EP), which has been associated with considerable economic losses due to reduced daily weight gain and feed efficiency. Adhesion cilia important for Mhp colonize respiratory epithelium. Therefore, a successful vaccine must induce broad Mhp-specific immune responses at mucosal surface. Recombinant attenuated Salmonella strains are believed act as powerful live vectors that able elicit against...
In recent years, food safety incidents caused by Escherichia coli have occurred and endangered human health. Due to the complex matrix of milk samples long pretreatment time, existing methods cannot quickly detect E. in samples. It is necessary enrich improve detection sensitivity. The outer membrane protein A (OmpA) widely present on cell may be used as a new target coli. this study, purified recombinant OmpA was immunize BALB/c mice produce polyclonal antibody. Immunomagnetic beads were...
Abstract Background Bacterial surface proteins play key roles in pathogenicity and often contribute to microbial adhesion invasion. Pasteurella lipoprotein E (PlpE), a multocida ( P. ) protein, has recently been identified as potential vaccine candidate. Live attenuated Salmonella strains have number of advantages vectors, including immunization with live vector can mimic natural infections by organisms, lead the induction mucosal, humoral, cellular immune responses. In this study,...
Abstract The Tol-Pal system of Gram-negative bacteria is necessary for maintaining outer membrane integrity. It a multiprotein complex five envelope proteins, TolQ, TolR, TolA, TolB, and Pal. These proteins were first investigated in E. coli , subsequently been identified many other bacterial genera. However, the function Salmonella Choleraesuis pathogenesis still unclear. Here, we reported role three these phenotype biology S. Choleraesuis. We found that mutations tolA tolB tolR caused...