A5051762810- Bone Tissue Engineering Materials
- Periodontal Regeneration and Treatments
- Osteoarthritis Treatment and Mechanisms
- Mesenchymal stem cell research
- Bone Metabolism and Diseases
- Dental Implant Techniques and Outcomes
- Electrospun Nanofibers in Biomedical Applications
- Bone and Dental Protein Studies
- Tissue Engineering and Regenerative Medicine
- Orthopaedic implants and arthroplasty
- Oral microbiology and periodontitis research
- Inflammatory mediators and NSAID effects
- Nanoplatforms for cancer theranostics
- Extracellular vesicles in disease
- Bone health and treatments
- Graphene and Nanomaterials Applications
- biodegradable polymer synthesis and properties
- dental development and anomalies
- Proteoglycans and glycosaminoglycans research
- Bone health and osteoporosis research
- Endodontics and Root Canal Treatments
- 3D Printing in Biomedical Research
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Bone and Joint Diseases
Griffith University
2022-2025
Australian Regenerative Medicine Institute
2014-2025
Guangzhou Medical University
2018-2025
Zhejiang Chinese Medical University
2014-2025
Haikou City People's Hospital
2019-2025
Central South University
2019-2025
University of Würzburg
2025
Jiaxing University
2025
Xuzhou Medical College
2025
Shandong Academy of Agricultural Sciences
2025
As direct effector cells for osteogenesis, osteoblastic are commonly used evaluating the in vitro osteogenic capacity of bone biomaterials, and traditional biological principle developing biomaterials is to directly stimulate differentiation. With this principle, most efforts currently spent on optimizing bio-mechanical physicochemical properties induce differentiation mesenchymal stem cells. This strategy has achieved certain success development biomaterials; however, inconsistencies...
Intestinal IgA, which is regulated by gut microbiota, has a crucial role in maintenance of intestinal homeostasis and protecting the intestines from inflammation. However, means microbiota promotes IgA responses remain unclear. Emerging evidence suggests that host can sense bacterial metabolites addition to pathogen-associated molecular patterns recognition these small molecules influences immune response beyond. We reported here metabolite short-chain fatty acid acetate promoted responses,...
Osteoimmunomodulation has informed the importance of modulating a favorable osteoimmune environment for successful materials-mediated bone regeneration. Nanotopography is regarded as valuable strategy developing advanced materials, due to its positive effects on enhancing osteogenic differentiation. In addition this direct effect osteoblastic lineage cells, nanotopography also plays vital role in regulating immune responses, which makes it possible utilize immunomodulatory properties create...
Silicon (Si) is a trace element, which plays an important role in human bone growth. Si has been incorporated into biomaterials for regeneration order to improve their osteogenic potential, both vitro and vivo. Little known, however, as how ions elicit biological response on bone-forming cells. The aim of this study was investigate the effect proliferation, differentiation, bone-related gene expression cell signalling pathways marrow stromal cells (BMSCs) by comparing BMSC responses...
The regeneration of lost periodontal apparatus in periodontitis treatment remains a clinical challenge due to the limited regenerative capacity cementum, ligament and alveolar bone condition. For tissue regeneration, it is essential regulate inflammatory response subsequent differentiation cells under condition infectious nature disease. In this study, was noted that 45 nm gold nanoparticles (AuNPs) could exhibit significant anti-inflammatory effect improve microenvironment via regulating...
The treatment of melanoma requires complete removal tumor cells and simultaneous tissue regeneration tumor-initiated cutaneous defects. Herein, copper silicate hollow microspheres (CSO HMSs)-incorporated bioactive scaffolds were designed for chemo-photothermal therapy skin cancers tissue. CSO HMSs synthesized with interior external nanoneedle microstructure, showing excellent drug-loading capacity photothermal effects. With incorporation drug-loaded into the electrospun scaffolds, composite...
The skeletal system is the basis of vertebral body composition, which affords stabilization sites for muscle attachment, protects vital organs, stores mineral ions, supplies places to hematopoietic system, and participates in complex endocrine immune system. Not surprisingly, bones are constantly reabsorbed, formed, remodeled under physiological conditions. Once bone metabolic homeostasis interrupted (including inflammation, tumors, fractures, diseases), rapidly initiates regeneration...