A5000103249- Immunodeficiency and Autoimmune Disorders
- Cytomegalovirus and herpesvirus research
- Terahertz technology and applications
- Genetic Neurodegenerative Diseases
- Physics of Superconductivity and Magnetism
- Blood disorders and treatments
- Biochemical and Molecular Research
- High Altitude and Hypoxia
- Immune Cell Function and Interaction
- Mitochondrial Function and Pathology
- Superconducting and THz Device Technology
- Semiconductor materials and devices
- Photonic Crystals and Applications
- Adenosine and Purinergic Signaling
- Genetics and Neurodevelopmental Disorders
- Platelet Disorders and Treatments
- Advancements in Semiconductor Devices and Circuit Design
- Silicon Nanostructures and Photoluminescence
- Respiratory and Cough-Related Research
- Signaling Pathways in Disease
- Nanowire Synthesis and Applications
- Mycobacterium research and diagnosis
- Congenital Ear and Nasal Anomalies
- Biochemical and Structural Characterization
- Peptidase Inhibition and Analysis
Istanbul University-Cerrahpaşa
2023-2025
Friedrich-Alexander-Universität Erlangen-Nürnberg
2015-2016
Izmir Institute of Technology
2009-2010
Objective: Prolidase deficiency is a metabolic and immunological disorder that inherited in an autosomal recessive manner. In prolidase deficiency, broad spectrum of differences observed patients, ranging from asymptomatic to multisystem involvement. There scarce information the literature on atypical features immunophenotypes this disease. Aim study present 4 new cases provide rare disease raise awareness. Materials Methods: This included female patients with deficiency. Their demographic,...
Abstract The group of patients with DNA‐repair‐defects increases susceptibility to infections due impaired repertoire diversity. In this context, we aimed investigate the TCRvβ‐repertoire by flow cytometric analysis and its correlation clinical entities in a IEI DNA repair defects. Peripheral lymphocyte subset analyses were performed analysis. aim was explore changing TCR‐Vβ‐repertoire that can predict some investigating using flow‐cytometric‐analysis‐based TCR‐Vβ interaction TCR‐repertoire...
Abstract Background Artemis deficiency is an autosomal recessive disorder characterized by a combined immunodeficiency with increased cellular radiosensitivity. In this review, the clinical and genetic characteristics of 15 patients DCLRE1C variants are presented. Methods The demographic, clinical, immunologic, confirmed diagnosed between 2013 2023 were collected retrospectively. Three evaluated for radiosensitivity Comet assay, compared age‐ sex‐matched healthy control. Results Seven who...
Immunoglobulin G replacement therapy (IgRT), intravenous (IV) and subcutaneous (SC) routes, is pivotal in treatment of primary immunodeficiencies (PID). In recent years, facilitated immunoglobulin (fSCIG), a combination rHuPH20 10% IgG has emerged as delivery method to combine advantages both IV SC.
In this work we demonstrate the fabrication of germanium nanoparticle (NP) based electronics. The whole process chain from production up to point inverter integration is covered. Ge NPs with a mean diameter 33 nm and geometric standard deviation 1.19 are synthesized in gas phase by thermal decomposition GeH4 precursor seeded growth process. Dispersions these particles ethanol employed fabricate thin particulate films (60 120 thickness) on substrates pre-patterned interdigitated aluminum...
Abstract Inborn errors of immunity include multiple genetic abnormalities affecting different components the innate and adaptive immune systems. More than 450 genes have been described so far including DNA repair defects which may result in predisposition to infections, but also malignancies, neurologic growth retardation. The group patients with methylation exhibit impaired immunity, increases susceptibility infections due repertoire diversity. In this context, we aimed investigate TCRvβ...
Abstract Background Purine nucleoside phosphorylase (PNP) deficiency is a rare autosomal recessive combined immunodeficiency. The phenotype profound T-cell with variable B- and NK-cell functions results in recurrent persistent infections that typically begin the first year of life. Neurologic findings occur approximately two-thirds patients. mechanism neurologic abnormalities unclear. Hematopoietic stem cell transplantation (HSCT) only curative treatment for PNP deficiency. Methods We report...
Rectangular intrinsic Josephson junction mesa structures of superconducting Bi <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> Sr CaCu O xmlns:xlink="http://www.w3.org/1999/xlink">8+Δ</sub> (Bi2212) can be used as a source continuous, coherent and polarized terahertz (THz) radiation. THz emitting mesas are below certain underdoped level Bi2212. They have small critical current in contrast to optimally doped overdoped We deposited...
Generation of powerful THz radiation from intrinsic Josephson Junctions (IJJs) Bi <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> Sr CaCu O xmlns:xlink="http://www.w3.org/1999/xlink">8+¿</sub> (Bi2212) may require mesas with large lateral dimension. However, there are difficulties in fabrication perfect rectangular mesas. Mesa angles should be close to 90 degrees obtain IJJs same planar dimensions for synchronization IJJs. Since thick...