A5101585306- Urological Disorders and Treatments
- Testicular diseases and treatments
- Sperm and Testicular Function
- Urologic and reproductive health conditions
- Sexual Differentiation and Disorders
- Urinary and Genital Oncology Studies
- Pediatric Urology and Nephrology Studies
- Cerebrovascular and Carotid Artery Diseases
- Ureteral procedures and complications
- Intracranial Aneurysms: Treatment and Complications
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Animal Genetics and Reproduction
- Renal and related cancers
- Reproductive Biology and Fertility
- Pregnancy-related medical research
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Cardiac Arrhythmias and Treatments
- CRISPR and Genetic Engineering
- Epigenetics and DNA Methylation
- Renal cell carcinoma treatment
- Multiple and Secondary Primary Cancers
- Urinary Tract Infections Management
- Neonatal Health and Biochemistry
- Uterine Myomas and Treatments
Anjo Kosei Hospital
2023-2025
Nagoya City University
2012-2024
Rakuwakai Otowa Hospital
2017-2024
Tokyo Women's Medical University
2022-2024
Kyoto Prefectural University
2023
Nara Medical University
2019-2020
Yao Tokushukai General Hospital
2010-2019
Mizuho (Japan)
2014-2018
The University of Tokyo
2014
Fukushima Medical University
2014
No AccessJournal of UrologyInvestigative Urology1 Apr 2014Expression Profiling microRNA in Cryptorchid Testes: miR-135a Contributes to the Maintenance Spermatogonial Stem Cells by Regulating FoxO1 Yoshinobu Moritoki, Yutaro Hayashi, Kentaro Mizuno, Hideyuki Kamisawa, Hidenori Nishio, Satoshi Kurokawa, Shinya Ugawa, Yoshiyuki Kojima, and Kenjiro Kohri MoritokiYoshinobu Moritoki Department Nephro-Urology, Graduate School Medical Sciences, Nagoya City University, Nagoya, Japan , HayashiYutaro...
To report our initial experience with robot-assisted laparoscopic extravesical ureteral reimplantation using the advancement technique.A total of 15 ureters from nine patients (age range 2-25 years) underwent for management vesicoureteral reflux. The reflux was classified as grade I in one ureter, II two ureters, III seven IV three and V ureters. One five female had a bilateral duplex system, observed all four da Vinci surgical system utilized. Ureteral carried out cases. We also compared...
ABSTRACT Background Clinical trials rarely focus on elder patients with castration‐resistant prostate cancer (CRPC), and data the outcomes of second‐generation androgen receptor signaling inhibitors (ARSIs) remain limited. Methods The ENABLE study for was an investigator‐initiated, multicenter, randomized controlled trial conducted in Japan to compare enzalutamide (ENZ) abiraterone plus prednisolone (ABI). This sub‐analysis performed evaluate efficacy safety profiles between aged ≥ 75...
Objectives: To investigate influence for the testicular development and to assess usefulness as an animal model, cryptorchid rats were induced by exposure flutamide during fetal period their testes examined histologically. Methods: Flutamide was injected into abdomen of pregnant 7 days from 14th 20th day gestation. The male offspring in which cryptorchidism observed at 28 after birth defined model rats. They divided four groups dosage (2.5 mg, 5 7.5 15 mg per day), weight, spermatogenesis...
To determine the effect of prostate weight on preoperative and postoperative outcomes robotic-assisted laparoscopic radical prostatectomy with a posterior approach to seminal vesicle. This retrospective study examined prospectively collected data 219 prostatectomies performed from May 2011 February 2013. Patients were divided into four groups based pathologic weight: <30 g, 30–49 50–79 ≥80 g. Continence sexual function assessed using validated questionnaires. Of patients, 19, 143, 51, 6 had...
Osteonecrosis of the jaw induced by administration bisphosphonates (BPs), BP-related osteonecrosis (BRONJ), typically develops after tooth extraction and is medically challenging. As BPs inhibit oral mucosal cell growth, we hypothesized that suppression wound healing-inhibiting effects could prevent BRONJ onset extraction. Since basic fibroblast growth factor (bFGF) promotes healing, but has a short half-life, examined whether initiation be prevented applying bFGF-containing gelatin hydrogel...
Urethrocutaneous fistula is a common complication of urethroplasty for severe hypospadias, even when microsurgical technique applied.From June 2001 to July 2003, we applied the scrotal dartos flap wrapping prevent occurrence urethrocutaneous in 14 patients with hypospadias.Hypospadias was repaired without formation all but one patient, who developed tiny which later closed successfully by simple procedure.We recommend covering neourethra well-vascularized because fewer complications,...
The most appropriate period for orchiopexy is controversial. We performed histological analyses of undescended testes to evaluate the influence timing in an experimental cryptorchid rat model. Furthermore, we extrapolated humans from our results.Experimental rats were induced with androgen blocker by injecting flutamide into abdomen pregnant Sprague-Dawley (Chubu Kagaku Shizai, Nagoya, Japan) 7 days 14 20 gestation. Approximately 90% male newborns had and on them 4, 5 weeks after birth....
<h3>BACKGROUND AND PURPOSE:</h3> Restenosis after CAS is a postoperative problem, with reported frequency of approximately 2%–8%. However differences in stent design, procedure, and the antiplatelet agent appear to affect incidence restenosis. We assessed restenosis effect CLZ preventing by standard procedure using CWS. <h3>MATERIALS METHODS:</h3> Between May 2010 October 2011, 62 lesions 60 consecutive patients underwent CWS at 4 medical institutions, all were followed clinically...
Objectives: In hypospadia patients, the urethral plate and underlying tissue were previously thought to be main cause of penile curvature and, because this, they used excised correct curvature. Currently, are preserved as not anymore. The aim present histology study was elucidate characteristic structure beneath plate. Methods: experimental group consisted 27 hypospadiac patients with moderately severe curvature, who underwent one‐stage urethroplasty after dividing Excised tissues observed...
No AccessJournal of UrologyPediatric Urology1 Aug 2014Elucidation Distinctive Genomic DNA Structures in Patients with 46,XX Testicular Disorders Sex Development Using Genome Wide Analyses Kentaro Mizuno, Yoshiyuki Kojima, Hideyuki Kamisawa, Yoshinobu Moritoki, Hidenori Nishio, Akihiro Nakane, Satoshi Kurokawa, Kenjiro Kohri, and Yutaro Hayashi MizunoKentaro Mizuno , KojimaYoshiyuki Kojima KamisawaHideyuki Kamisawa MoritokiYoshinobu Moritoki NishioHidenori Nishio NakaneAkihiro Nakane...
Robot-assisted radical prostatectomy (RARP) is commonly performed using the transperitoneal (TP) approach with six trocars over an 8-cm distance in steep Trendelenburg position. In this study, we investigated feasibility and benefit of extraperitoneal (EP) a 4-cm flat or 5° We also introduced four new steps to surgical procedure compared results complications between EP TP propensity score matching. Between August 2012 2016, 200 consecutive patients without any physical restrictions...
In cryptorchidism, germ cell development failure presents from infancy and may be reflected by altered hormonal levels produced Sertoli cells. Our object was to assess for associations between serum hormone testicular histopathology in cryptorchidism with an infertility risk according the pretreatment undescended positions.Prepubertal cryptorchid boys aged 7-91 (median 20) months who underwent orchidopexy 2014 2019 were included (122 unilateral [median 19 {range 7-91}], 23 bilateral [24...
Epidermal growth factor (EGF) is secreted mainly from the submandibular glands. Submandibular gland ablation causes a marked decrease in male fertility, which suggests that EGF influences spermatogenesis. We investigated effect of combination with orchiopexy on cryptorchid rat testes tubular deterioration had become partially irreversible.Unilaterally rats were obtained by daily administration 7.5 mg flutamide (Nihonkayaku, Tokyo, Japan), an androgen receptor antagonist, to pregnant rats. At...
Cryptorchidism is known to impair spermatogenesis. The blood-testis barrier (BTB) becomes defined in seminiferous tubules around puberty and provides a suitable environment for germ cells. Little about the BTB undescended testes (UDT).To determine role of during UDT using non-surgical cryptorchid rat model.Unilateral male rats were intraperitoneally injected with non-steroidal antiandrogen intrauterine development; harvested at 4, 5, 6 weeks after birth. Testicular histology, expression...
To restore fertility the current consensus suggests early orchiopexy for cryptorchidism. However, despite it is reported that transformation of gonocytes into adult dark spermatogonia already impaired at time surgery and consequently affects future fertility. elucidate biological processes occurring during germ cell maturation in cryptorchid testis, we identified genes affected by testicular maldescent using polymerase chain reaction based suppression subtractive hybridization, investigated...
Abstract Hemiscrotal agenesis is among the rarest anomalies in scrotal development disorders. As it has only been reported three cases, clinical manifestations remain unclear. We report a case of hemiscrotal with ipsilateral cryptorchidism. Based on thermal assessment scrotum, concurrent scrotoplasty and orchiopexy were carried out, improved environment fixed left testis. Furthermore, low expression androgen receptor steroid‐5‐alpha‐reductase, alpha polypeptide 2 affected side scrotum likely...
Abstract Background and Objectives We aimed to examine the effect of preoperative three‐dimensional (3D) computed tomography (CT)‐based resection process map (RPM) imaging on outcomes robot‐assisted partial nephrectomy (RAPN). Methods retrospectively analyzed 177 patients (RPM group, n = 92; non‐RPM 85) who underwent this surgery between November 2012 April 2022. Patient‐specific contrast‐enhanced CT images were used construct an RPM, a 3D representation kidney showing planned tumor 5 mm...