A5077496785- Urinary Bladder and Prostate Research
- Prostate Cancer Diagnosis and Treatment
- Pelvic floor disorders treatments
- Bladder and Urothelial Cancer Treatments
- Urological Disorders and Treatments
- Prostate Cancer Treatment and Research
- Urinary Tract Infections Management
- Hormonal and reproductive studies
- Radiopharmaceutical Chemistry and Applications
- Renal and related cancers
- Renal cell carcinoma treatment
- Ferroptosis and cancer prognosis
- Urologic and reproductive health conditions
- Cancer Immunotherapy and Biomarkers
- Cancer Cells and Metastasis
- Urinary and Genital Oncology Studies
- Testicular diseases and treatments
- Immunotherapy and Immune Responses
- Adrenal Hormones and Disorders
- Pediatric Urology and Nephrology Studies
- Cancer Mechanisms and Therapy
- Cancer, Hypoxia, and Metabolism
- Neuroendocrine Tumor Research Advances
- Ureteral procedures and complications
- Cytokine Signaling Pathways and Interactions
Fukushima Medical University
2016-2025
John Wiley & Sons (United States)
2018
Hudson Institute
2018
Tochigi Cancer Center
2009-2017
National Institutes of Health
2009
National Cancer Institute
2009
Tohoku University
2000
ABSTRACT Background Clinical trials rarely focus on elder patients with castration‐resistant prostate cancer (CRPC), and data the outcomes of second‐generation androgen receptor signaling inhibitors (ARSIs) remain limited. Methods The ENABLE study for was an investigator‐initiated, multicenter, randomized controlled trial conducted in Japan to compare enzalutamide (ENZ) abiraterone plus prednisolone (ABI). This sub‐analysis performed evaluate efficacy safety profiles between aged ≥ 75...
This study investigated whether preoperative patient characteristics and surgery-related factors affect postoperative de novo overactive bladder (OAB) after robot-assisted radical prostatectomy (RARP), identified three predictive markers. Patients without OAB who underwent RARP at our hospital between February 2013 October 2020 were included. At 12 months post-RARP, patients divided into OAB-free groups based on the presence of bladder. Preoperative compared two groups. A total 404 analyzed...
To identify predictors of prolonged severe urinary incontinence after robot-assisted radical prostatectomy (RARP), perioperative clinical parameters were investigated. Participants 299 patients who underwent RARP at our institute. Prolonged was defined as a 1-h (one-hour) pad test >50 g/h and/or use >3 pads/day 12 months RARP. The cohort divided into and non-severe groups according to this criterion. Perioperative compared between for Twenty-seven (9.0%) categorized the group. remaining 272...
ABSTRACT Introduction A case of muscle‐invasive bladder cancer and renal granulomatosis that developed after intravesical Bacillus Calmette‐Guérin therapy, in which a combination neoadjuvant gemcitabine‐cisplatin anti‐tuberculosis therapy was safely administered, radical cystectomy ultimately performed, is reported. Case Presentation 64‐year‐old man with non‐muscle‐invasive underwent transurethral resection every time recurred. However, the patient left during treatment. Anti‐tuberculosis...
ABSTRACT Introduction A case of bilateral high intra‐abdominal testes successfully treated with multistage Fowler–Stephens orchiopexy is reported. Case Presentation 6‐month‐old boy nonpalpable was diagnosed a left testis located immediately caudal to the spleen on magnetic resonance imaging and laparoscopy. At age 4 years, diffusion‐weighted detected structure liver, which suspected be right testis. With diagnosis testes, one‐stage performed at 5 years age. After confirming its development,...
We present our experience with a novel three-layer two-step posterior reconstruction (PR) technique using peritoneum during robot-assisted radical prostatectomy (RARP) to improve recovery of postoperative urinary continence.Forty-eight patients localized prostate cancer were enrolled in this study and divided randomly into two groups, which treated by the standard PR (standard group; n = 24) or (three-layer RARP. prospectively analyzed continence rate 1-hour pad test. All underwent...
Enzalutamide (ENZ) and abiraterone plus prednisolone (ABI) can improve the survival of patients with castration-resistant prostate cancer (CRPC). However, agent that is more effective against nonmetastatic CRPC remains unclear. To evaluate be used as first-line treatment for CRPC, an investigator-initiated, multicenter, randomized controlled trial (ENABLE Study PCa) including both metastatic was conducted in Japan. The prostate-specific antigen (PSA) response rate, overall survival, some...
Purpose:We assessed the stiffness of unilateral undescended testes after orchiopexy, examining its value in tracking histopathological changes and fertility potential during postoperative follow-up. Additionally, we explored optimal timing for surgery based on testicular stiffness.
Prostate-specific membrane antigen (PSMA)-targeted alpha therapy is considered a promising alternative treatment for metastatic castration-resistant prostate cancer (mCRPC). Though astatine-211 (211At) potentially useful alpha-emitter producible by cyclotrons, its clinical application has been limited instability and tendency to deastatination in vivo. To overcome these challenges, we developed [211At]At-NpG-PSMA, novel PSMA ligand with neopentyl-glycol structure that enhances vivo stability...
Background To investigate the possible pathogenesis of benign prostatic enlargement (BPE) induced by local atherosclerosis, association between atherosclerosis and was investigated, molecular biological analyses were performed using human prostatectomy specimens. Methods A total 69 consecutive patients who underwent robot‐assisted radical (RARP) participated in this prospective study. evaluate actual arteries removed during RARP. Microscopic assessment classified as one three degrees...
Objectives To elucidate the effect of postoperative urinary incontinence on nocturia‐related quality life after robot‐assisted radical prostatectomy. Methods A total 100 consecutive patients who underwent prostatectomy completed a nocturia questionnaire score and frequency‐volume chart before surgery. These were divided into two groups by continence status (continent incontinent) according to number pad exchanges per day 1‐h test Assessment was carried out surgery, then at 3 12 months...