- NF-κB Signaling Pathways
- Genital Health and Disease
- Inflammatory mediators and NSAID effects
- Tendon Structure and Treatment
- Osteoarthritis Treatment and Mechanisms
- RNA Research and Splicing
- Sports injuries and prevention
- Cancer-related molecular mechanisms research
- Natural product bioactivities and synthesis
Shantou University
2018-2023
Yue Bei People's Hospital
2018-2023
Shantou University Medical College
2022
Tendinopathy is mainly characterized by local pain, functional limitation and decreased athletic ability, which seriously affects the quality of life patients career athletes. Farrerol (FA), one main active compounds extracted from Rhododendron plants in family, has a wide range pharmacological activities, such as immunomodulatory, anti-inflammatory antiviral effects. However, effect FA on tendinopathy unclear. Here, we investigated mechanism tendon injury through collagenase-induced vivo...
Osteoarthritis (OA) is one of the most common diseases in orthopedic clinic, characterized by progressive cartilage degradation. RNA-binding proteins (RBPs) are capable binding to RNAs at transcription and translation levels, playing an important role pathogenesis OA. This study aims investigate diagnosis values RBP-related genes The RBPs were collected from previous studies, GSE114007 dataset (control = 18, OA 20) was downloaded Gene Expression Omnibus (GEO) as training cohort. Through...