Yongfu Wu

ORCID: 0000-0002-1245-251X
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About
Contact & Profiles
Research Areas
  • Asthma and respiratory diseases
  • RNA modifications and cancer
  • Folate and B Vitamins Research
  • Cancer-related Molecular Pathways
  • Epigenetics and DNA Methylation
  • Alzheimer's disease research and treatments
  • Heterotopic Ossification and Related Conditions
  • Molecular Biology Techniques and Applications
  • Tendon Structure and Treatment
  • Respiratory Support and Mechanisms
  • Genetic Associations and Epidemiology
  • Pharmacological Effects of Natural Compounds
  • Dermatological and Skeletal Disorders
  • Sports injuries and prevention
  • Ginger and Zingiberaceae research
  • Hydrogen's biological and therapeutic effects
  • Drug-Induced Hepatotoxicity and Protection
  • Cancer Immunotherapy and Biomarkers
  • Chemical Reactions and Isotopes
  • Air Quality and Health Impacts
  • Genital Health and Disease
  • Nuclear Receptors and Signaling
  • Barrier Structure and Function Studies
  • Neonatal Respiratory Health Research
  • Peroxisome Proliferator-Activated Receptors

Gansu Agricultural University
2024

Longdong University
2024

Shantou University
2017-2024

Yue Bei People's Hospital
2017-2024

Southern Medical University
2024

Shantou University Medical College
2022-2024

Guangdong Medical College
2013-2020

Affiliated Hospital of Guangdong Medical College Hospital
2016-2019

The blood-brain barrier (BBB) is essential for the exchange of nutrient and ions to maintain homeostasis central nervous system (CNS). BBB dysfunction commonly associated with disruption endothelial tight junctions excess permeability, which results in various CNS diseases. Therefore, function crucial prevent or treat disorders. Here, we show that serum starvation disrupted as evidenced by decreased trans-endothelial resistance, increased redistribution junction proteins such Claudin-5...

10.3389/fphys.2019.00002 article EN cc-by Frontiers in Physiology 2019-01-17

Tendinopathy is mainly characterized by local pain, functional limitation and decreased athletic ability, which seriously affects the quality of life patients career athletes. Farrerol (FA), one main active compounds extracted from Rhododendron plants in family, has a wide range pharmacological activities, such as immunomodulatory, anti-inflammatory antiviral effects. However, effect FA on tendinopathy unclear. Here, we investigated mechanism tendon injury through collagenase-induced vivo...

10.1111/jcmm.17388 article EN cc-by Journal of Cellular and Molecular Medicine 2022-05-18

The pathogenesis of trauma-induced heterotopic ossification (HO) in the tendon remains unclear, posing a challenging hurdle treatment. Recognizing inflammation as root cause HO, anti-inflammatory agents hold promise for its management. Malvidin (MA), possessing properties, emerges potential agent to impede HO progression. This study aimed investigate effect MA treating and unravel underlying mechanisms. Herein, effectiveness preventing formation was assessed through local injection rat...

10.1111/jcmm.18349 article EN cc-by Journal of Cellular and Molecular Medicine 2024-04-30

The zebrafish (Danio rerio) has recently been shown to be an ideal model study bone disease including osteoporosis. osteoporosis could induced by glucocorticoid treatment with chemical staining for reflecting the level of mineralization. However, this methodology was unstable. Here, we developed a novel directly evaluate mass and density.We generated used transgenic Tg (ola.sp7:nlsGFP) density measuring areal extent integrated optical (IOD) enhanced green fluorescent protein (eGFP). This...

10.1002/ame2.12000 article EN cc-by-nc Animal Models and Experimental Medicine 2018-03-01

The mechanisms regulating airway remodeling changes remain poorly understood. Recently, a smooth muscle progenitor cell was identified in the peripheral circulatory system that plays an important role reconstruction of injured blood vessels. However, to best our knowledge, there is no report medical literature regarding cells (SPCs) asthma.The aim this study investigate relationship between SPCs and development remodelling murine model asthma.Chronic asthma with generated by sensitizing...

10.12932/ap0395.32.3.2014 article EN Asian Pacific Journal of Allergy and Immunology 2013-11-15
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