A5067568881- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- NMR spectroscopy and applications
- MRI in cancer diagnosis
- Advanced NMR Techniques and Applications
- Electron Spin Resonance Studies
- Lanthanide and Transition Metal Complexes
- Medical Imaging Techniques and Applications
- Spine and Intervertebral Disc Pathology
- Cardiac Imaging and Diagnostics
- Photoacoustic and Ultrasonic Imaging
- Metabolomics and Mass Spectrometry Studies
- Electrocatalysts for Energy Conversion
- Atomic and Subatomic Physics Research
- Ultrasound and Hyperthermia Applications
- Musculoskeletal pain and rehabilitation
- Electrochemical Analysis and Applications
- Nutrition, Health and Food Behavior
- Food Quality and Safety Studies
- Advanced battery technologies research
- Ultrasound Imaging and Elastography
- Bone and Joint Diseases
- Intraoperative Neuromonitoring and Anesthetic Effects
- Genetic Neurodegenerative Diseases
- Inflammatory Biomarkers in Disease Prognosis
University of California, San Diego
2023-2025
Seoul National University
2025
University of California San Diego Medical Center
2024
Hyundai Motors (South Korea)
2023
University of California, Berkeley
2019-2022
Berkeley College
2020
National Cancer Center
2017-2019
Johns Hopkins University
2011-2016
Johns Hopkins Medicine
2016
Hanwha Techwin (South Korea)
2009-2012
Embryonic stem cells (ESCs) have attracted great interest in the fields of tissue engineering, regenerative medicine, and organogenesis for their pluripotency ability to self-renew. ESC aggregation, which produces an embryoid body (EB), has been widely utilized as a trigger vitro directed differentiation. In this paper, we propose novel method constructing large numbers deep concave wells PDMS microfluidic chips using meniscus induced by surface tension liquid prepolymer, applied chip mass...
Perfluorocarbon nanoemulsions (PFCNEs) have recently been undergoing rigorous study to investigate their ability improve the therapeutic efficacy of tumor ablation by high intensity focused ultrasound (HIFU).For precise control PFCNE delivery and thermal ablation, accumulation distribution in a should be quantitatively analyzed.Here, we used fluorine-19 ( 19 F) magnetic resonance imaging (MRI) track tumor, analyzed how intra-tumoral quantities affect HIFU treatment.Ablation outcomes were...
Purpose To investigate whether the magnitude of in vivo fluorine 19 (19F) magnetic resonance (MR) imaging signal is associated with subsequent development colitis-associated dysplasia after situ fluorination inflammatory macrophages a mouse model bowel disease (IBD). Materials and Methods Experiments were approved by institutional animal care use committee. Mice experimental group (n = 10) administered azoxymethane dextran sulfate sodium to induce dysplasia. Five mice noninduced control...
Myelin proton density fraction (MPDF) and myelin water (MWF) measured with short-TR adiabatic inversion-recovery (STAIR) sequences are potential biomarkers of aging neurodegeneration, but the effects on MPDF/MWF remain unknown. This study aims to assess relationships between age using 3D STAIR ultrashort echo time (STAIR-UTE) short (STAIR-STE) sequences, respectively. 42 volunteers (29 young (<55y), 13 old (>55y)), were recruited for MPDF MWF mapping white matter (WM) gray (GM) a 3 T...
The increasing need for scalable and efficient crop monitoring systems in industrial plant factories calls image-based deep learning models that are both accurate robust to domain variability. This study investigates the feasibility of CNN-based growth stage classification butterhead lettuce (Lactuca sativa L.) using two data types: raw images processed through GrabCut–Watershed segmentation. A ResNet50-based transfer model was trained evaluated on each dataset, cross-domain performance...
: The objective of this study was to assess the bi-exponential relaxation times and fractions short long components human patellar tendon ex vivo using three-dimensional ultrashort echo time T1ρ (3D UTE-T1ρ) imaging.
Purpose To investigate whether high-intensity focused ultrasound (HIFU)-induced macrophage infiltration could be longitudinally monitored with fluorine 19 (19F) magnetic resonance (MR) imaging in a quantitative manner. Materials and Methods BALB/c mice were subcutaneously inoculated 4T1 cells separated into three groups: untreated (control, n = 9), HIFU-treated (HIFU, HIFU- clodronate-treated (HIFU+Clod, 9). Immediately after HIFU treatment, all intravenously given perfluorocarbon (PFC)...
Direct imaging of semi-solid lipids, such as myelin, is great interest a noninvasive biomarker neurodegenerative diseases. Yet, the short T
Purpose Renal function is characterized by concentration of urea for removal in urine. We tested as a CEST‐MRI contrast agent measurement the concentrating capacity distinct renal anatomical regions. Methods The CEST was examined using phantoms with different concentrations and pH levels. Ten C57BL/6J mice were scanned twice at 7 T, once following intraperitoneal injection 2M 150 µL separately an identical volume saline. Kidneys segmented into regions encompassing cortex, outer medulla,...
The presence of tumor-associated macrophages (TAMs) is significantly associated with poor prognosis tumors. Currently, magnetic resonance imaging- (MRI-) based TAM imaging methods that use nanoparticles such as superparamagnetic iron oxide and perfluorocarbon nanoemulsions are available for quantitative monitoring burden in However, whether MRI-based measurements TAMs can be used prognostic markers has not been evaluated yet. In this study, we positron emission tomography (PET) 18...
Abstract Purpose To investigate the feasibility and application of a novel imaging technique, three-dimensional dual adiabatic inversion recovery prepared ultrashort echo time (3D DIR-UTE) sequence, for high contrast assessment cartilaginous endplate (CEP) with head-to-head comparisons between other UTE techniques. Method The DIR-UTE sequence employs two narrow-band full passage (AFP) pulses to suppress signals from long T 2 water (e.g., nucleus pulposus (NP)) bone marrow fat (BMF)...
Introduction: Many spine disorders are caused by disc degeneration or endplate defects. Because nutrients entering the avascular channeled through cartilaginous (CEP), structural and compositional changes in CEP may block this solute channel, thereby hindering cell function. Therefore, imaging region is important to improve diagnostic accuracy of disorders. Methods: A clinically available T1-weighted fat-suppressed spoiled gradient recalled-echo (FS-SPGR) sequence was optimized for...
Purpose Standardized blood tests often lack adequate sensitivity and specificity to capture the gradual progression of renal injuries. We suggest a multiparametric molecular MRI approach as noninvasive tool for monitoring function loss distinguishing different types Methods CEST quantitative magnetization transfer (qMT) imaging were performed on cisplatin ( n = 16) aristolochic acid (AA)‐induced nephropathy 22) mouse models at 7T with an infusion either saline or urea. Seven‐pool Lorentzian...
우리나라에서 유일하게 사용되고 있는 유기염소계 살충제 endosulfan을 미생물학적 방법으로 분해하기 위하여 총 182점의 토양, 퇴비 및 액상의 미생물 시료를 접종원으로 실시한 endosulfan 집식(enrichment) 실험으로부터 diol 형태로 경유하여 분해하는 균주를 선발하고 그 이름을 Bacillus sp. E64-2로 명명하였다. 분리균주는 7일만에 배지에 함유된 10 mg/L 농도의 99% 이상 분해하였다. 또한 분리균주 E64-2의 조효소액은 diol로 전환하는 활성을 가지고 있었으며 균주 자체는 생육 중에 배지의 pH를 배양 7일 만에 pH 7.0에서 8.4로 올릴 수 있었다. 이러한 효소활성과 증가 능력은 E64-2에 의한 분해의 주된 작용 인자인 것으로 판단되며 이 균주는 효소에 분해작용과 상승작용을 통하여 토양에 잔류는 난분해성 물질인 bioremediation하기 위한 연구의 기초 균주로서의 가치가있을 판단된다. A bacterium, which...
<TEX>$TiO_2$</TEX>가 첨가된 탄소복합전극을 제조 Capacitive deionization(CDI)에서의 제염효과에 대하여 고찰하였다. 본 연구에서는 탄소전극과 제조하여 순환전류전압법과 충전-방전 평가를 하였으며 이때의 이온제거율에 순환전류전압법으로 1 mV/s의 전위주사속도에서 측정한 결과 탄소전극은 125 F/g, 탄소복합전극의 축전용량은 243 F/g으로 2배 증가됨을 확인하였다. <TEX>$TiO_2$</TEX>의 함량은 10 wt.%로 고정하였으며 첨가됨에 따라 전기이중층 흡착량이 증가되어 이온제거율이 탄소전극보다 25% 증가되었다. Desalination effects of deionization(CDI) process using activated carbon <TEX>$TiO_2$</TEX> composite electrode. In this study, we made the electrod and electrode, which analysed at...