A5100737721- Retinal Diseases and Treatments
- Pharmacological Effects and Toxicity Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Ocular Surface and Contact Lens
- Epilepsy research and treatment
- Corneal surgery and disorders
- Diet and metabolism studies
- Diabetes Treatment and Management
- Corneal Surgery and Treatments
- Nutritional Studies and Diet
- Inflammatory Biomarkers in Disease Prognosis
- MXene and MAX Phase Materials
- Hepatitis C virus research
- Tea Polyphenols and Effects
- Trace Elements in Health
- Curcumin's Biomedical Applications
- Antioxidant Activity and Oxidative Stress
- Glaucoma and retinal disorders
- Acute Ischemic Stroke Management
- Urticaria and Related Conditions
- Vascular Malformations Diagnosis and Treatment
- Biochemical effects in animals
- Connexins and lens biology
- Mast cells and histamine
- Bipolar Disorder and Treatment
Sun Yat-sen University
2022-2025
Fifth Affiliated Hospital of Sun Yat-sen University
2022-2025
Shaanxi Normal University
2024
Shangqiu First People's Hospital
2024
Harbin Medical University
2019
Second Affiliated Hospital of Harbin Medical University
2019
Beijing Hospital
2018
Wenzhou Medical University
2016
Abstract Lacosamide was the first approved third-generation antiepileptic drug. However, real-world data regarding its adverse cardiac reactions in large samples still need to be completed. We evaluated safety profile of lacosamide using Food and Drug Administration Adverse Event Reporting System (FAERS). performed disproportionality analysis computing reporting odds ratio (ROR) as a quantitative metric assess signal lacosamide-related events (AEs) from 2013 Q1 2022 Q4. The considered...
Globally, approximately 2.2 billion people suffer from visual impairments or blindness. Dietary patterns are closely associated with the prevalence of multiple ocular diseases. This study aimed to explore association between Composite Antioxidant Index (CDAI) and disorders. The data were derived 1706 subjects aged 40 years older who participated in 2005–2008 National Health Nutrition Examination Survey (NHANES), which utilized undersampling techniques. Trained staff interviewed participants...
This study was designed to verify the anti-obesity effect of dietary turmeric powder (TP) as a traditional cooking spice and its underlying mechanism. The HFD-fed C57BL/6J mice were supplemented with or without TP (8%) for 12 weeks. results indicated that glucolipid metabolism disorder high-fat diet (HFD)-fed significantly ameliorated through supplementation TP. consumption also induced beige-fat development brown adipose tissue (BAT)-derived nonshivering thermogenesis in obese mice. 16S...
Flexible wearable sensors have attracted considerable attention in the applications of biomedical, human-computer interaction, and many other fields. hydrogel-based stand out because their excellent flexibility and...
Purpose: The study aims to assess the efficacy of integrating macular buckling (MB) with pars plana vitrectomy (PPV), inverted internal limiting membrane (ILM) flap technique, and air tamponade in treating hole retinal detachment (MHRD) patients high myopia. Methods: This retrospective included sixty-two eyes from consecutive diagnosed highly myopic MHRD. participants were categorized into two groups: PPV group (n=34) combination (n=28). Best-corrected visual acuity (BCVA), axial length...
Copper, zinc, and selenium are essential trace elements for human have important effects on sex hormones. There few studies the relationships between three Therefore, our study aimed to investigate serum copper, testosterone, estradiol, SHBG using data from National Health Nutrition Examination Survey (NHANES) 2013-2016 in participants 6-19 years. 1097 were enrolled stratified into male/female children adolescents. Weighted linear regression models combined diagnosis used estimate hormones...
To study the role of luteolin (LUT) in expression toll-like receptors 3 (TLR3) ligand polyI:C stimulated inflammatory factors human corneal fibroblasts (HCFs).HCFs cells were cultivated with or without LUT polyI:C. The levels interleukin (IL)-6, IL-8, monocyte chemotactic protein-1 (MCP-1), vascular cell adhesion molecule (VCAM)-1, as well intercellular (ICAM)-1 measured using enzyme-linked immunosorbent assay (ELISA), immunoblotting reverse transcription-quantitative polymerase chain...
To evaluate the urinary levels of 8-oxo-7,8-dihydro-2'deoxyguanosine (8-oxo-dGsn) and 8-oxo-7,8-dihydroguanosine (8-oxo-Gsn) in liver injury patients with hepatitis B virus (HBV) infection to explore relationship between 8-oxo-dGsn or 8-oxo-Gsn degree damage. We enrolled 138 HBV 169 age- sex-matched healthy controls this study. A sensitive accurate isotope-diluted liquid chromatograph mass spectrometer/mass spectrometer (LC-MS/MS) method was used measure 8-oxo-dGsn. Simultaneously,...
Abstract Background Inflammation is associated with the pathophysiology of diabetic retinopathy (DR). Within framework complete dietary patterns, Dietary Inflammatory Index (DII) was formulated to evaluate inflammatory properties inherent in a diet. The main purpose current study assess relationship between DII and DR using National Health Nutrition Examination Survey (NHANES). Methods original sample size included 1,148 diabetes patients out 2005–2008 NHANES surveys. Twenty-four-hour...
Corneal epithelial barrier function is important to maintain corneal homeostasis and impaired by inflammation. We aimed investigate the localization of semaphorin 4D (Sema4D) in cornea, its effects on cultured cells.The expressions semaphorin4 D receptor murine cornea were examined immunoblot, immunofluorescent staining confocal microscopy observations. Human (HCE) cells stimulated TNF-α or IL-1β with without Sema4D. Cell viability was CCK8, cell migration evaluated scratch wound assay,...
This study was for the first time to reveal anti-obesity effect of summer-autumn tea aqueous extract (SATE) and its underlying mechanism. High-fat diet (HFD)-fed C57BL/6J mice were treated with...