A5072347158- HIV/AIDS Research and Interventions
- Plant Pathogens and Fungal Diseases
- Mycorrhizal Fungi and Plant Interactions
- HIV-related health complications and treatments
- Eating Disorders and Behaviors
- Children's Physical and Motor Development
- Hepatitis C virus research
- Yeasts and Rust Fungi Studies
- HIV Research and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Child Nutrition and Feeding Issues
- HIV/AIDS Impact and Responses
- Infant Development and Preterm Care
- Slime Mold and Myxomycetes Research
- Plant and Biological Electrophysiology Studies
- Attention Deficit Hyperactivity Disorder
- Statistical Methods and Inference
- Fungal and yeast genetics research
- Maternal Mental Health During Pregnancy and Postpartum
- Cerebral Palsy and Movement Disorders
- Statistical Methods and Bayesian Inference
- Obstructive Sleep Apnea Research
- Linguistics and Discourse Analysis
- Plant and animal studies
- Sleep and related disorders
Laboratoire Interdisciplinaire des Énergies de Demain
2020-2024
Université Paris Cité
2013-2024
Sorbonne Paris Cité
2014-2024
Centre National de la Recherche Scientifique
2023-2024
Délégation Paris 7
2015-2022
ORCID
2022
Fondation de France
2022
Fondation Santé des étudiants de France
2022
Hôpital Saint-Louis
2011-2019
Assistance Publique – Hôpitaux de Paris
2012-2017
Children with Developmental Coordination Disorder (DCD) are a group embracing clumsiness and developmental dyspraxia. Our study provides better understanding of the nature DCD its etiology, identifies subtypes Forty-three children (5-15 years) were enrolled on Diagnostic Statistical Manual Mental Disorders (4th ed. [DSM-IV-TR]; American Psychiatric Association, 2000) criteria. Extensive standardized evaluations conducted. We distinguished from two patterns "pure" dyspraxia: ideomotor...
As publishing is essential but competitive for researchers, difficulties in writing and submitting medical articles to biomedical journals are disabling. The DIAzePAM (Difficultés des Auteurs à la Publication d'Articles Médicaux) survey aimed assess the experienced by researchers AP-HP (Assistance Publique - Hôpitaux de Paris, i.e., Paris Hospitals Board, France), largest public health institution Europe, when preparing journals. also researchers' satisfaction perceived needs.A 39-item...
Direct oral anticoagulants (DOACs) have shown non-inferiority and ease of use compared to vitamin K antagonists (VKA) in the treatment venous thromboembolism (VTE). No study so far has been directed toward real-life experience outpatients receiving for VTE France.This is an observational descriptive epidemiological study, using three validated questionnaires (Morisky Medication Adherence Scale-8, EQ-5D, part 2 Perception Anticoagulant Treatment Questionnaire), assess adherence, quality life,...
Introduction: Direct oral anticoagulants (DOACs) have shown noninferiority to vitamin K antagonists (VKA) in stroke prevention patients with atrial fibrillation. DOAC treatment may be less demanding than VKA, improving quality of life. To date, there been no studies the real-life experience outpatients receiving anticoagulation therapy for fibrillation France. Methods: An observational descriptive epidemiological study used three validated questionnaires (EQ-5D, PACT-Q2, and MMAS-8 French...
This study reports the psychometric validation of a new HIV/AIDS-specific health-related quality life (HRQL) questionnaire, Patient Reported Outcomes Quality Life-HIV. The instrument was developed simultaneously across Europe, North and South America, Africa, Asia, Australia to assess multidimensional impairments in era highly active antiretroviral therapy.A cross-sectional performed 8 countries. pilot 70-item questionnaire co-administered with HIV symptoms index, EQ-5D Medical Study-HIV...
Background: Developmental Coordination Disorder (DCD) defines a heterogeneous class of children exhibiting marked impairment in motor coordination as general group deficits fine and gross motricity (subtype mixed group) common to all research studies, with variety other disorders that have been little investigated. No consensus about symptoms aetiology has established. Methods: Data from 58 aged 6 13 years DCD were collected on DSM-IV criteria, similar DSM- 5 criteria. They had no medical...
The order Sordariales is taxonomically diverse, and harbours many species with different lifestyles large economic importance. Despite its importance, a robust genome-scale phylogeny, associated comparative genomic analysis of the lacking. In this study, we examined whole-genome data from 99 Sordariales, including 52 newly sequenced genomes, seven outgroup taxa. We inferred comprehensive phylogeny that resolved several contentious relationships amongst families in order, cleared-up...
Recombination is often suppressed at sex-determining loci in plants and animals, self-incompatibility or mating-type fungi. In fungal ascomycetes, recombination suppression around the locus associated with pseudo-homothallism, i . e production of self-fertile dikaryotic sexual spores carrying two opposite mating types. This has been well studied species complexes from different families Sordariales : Podospora anserina Neurospora tetrasperma However, it unclear whether this intriguing...
Background: Electronic patient-reported outcomes (PRO) provide quick and usually reliable assessments of patients' health-related quality life (HRQL). Objective: An electronic version the Patient-Reported Outcomes Quality Life-human immunodeficiency virus (PROQOL-HIV) questionnaire was developed, its face validity reliability were assessed using standard psychometric methods. Methods: A sample 80 French outpatients (66% male, 52/79; mean age 46.7 years, SD 10.9) recruited. Paper-based...
Abstract Purpose Anorexia Nervosa (AN) is a severe chronic disorder and parents’ experience of caregiving usually marked by emotional distress burden. Severe psychiatric disorders are known to be linked with the concept grief. Grief has not been investigated in AN. The aim this study was explore adolescents’ characteristics that may related parental burden grief AN, link between these two dimensions. Methods Eighty mothers, 55 fathers their adolescents ( N = 84) hospitalized for AN...
Non-suicidal self-injury (NSSI) is frequent in eating disorders (ED). The aim of this study was to describe NSSI among subjects hospitalised for anorexia nervosa (AN) who self-harm and factors associated with population. This part a larger French longitudinal multi-centre study. Two hundred two women AN were recruited from inpatient treatment facilities ED 2009 2011. All participants fulfilled the DSM-5 diagnostic criteria AN. Subjects without compared clinical characteristics comorbidities...
Abstract Analyses of the genetic diversity well-studied fungi Sordariales order, such as Neurospora spp. and Podospora anserina (syn. Triangularia ), have shown that species classically defined by morphology are often complexes cryptic species. Here, we report on delimitation among 76 strains producing mycelium sexual reproductive structures identical to those pseudo-homothallic Schizothecium tetrasporum Neoschizothecium ). Their whole genomes were sequenced well six closely related but...
Recombination suppression often evolves around sex-determining loci and extends stepwise, resulting in adjacent regions with different levels of divergence between sex chromosomes, called evolutionary strata. In Ascomycota fungi, strata have been found the mating-type (MAT) locus only pseudo-homothallic species, i.e., a diploid-like lifecycle mycelia carrying nuclei both mating types. contrast, no recombination has observed fungi haploid-like lifecycle, such as heterothallic (with mycelial...
Parents with past and current eating disorders (ED) have been shown to report troubles nourishing their infants. This could increase the risk of infant feeding problems linked maternal anxiety depression. It is not clear how mothers' difficulties before pregnancy at time birth can affect infant's feeding. We aimed specify impact on adaptation sensitivity offspring during feeding, by comparing a population mothers controls. Twenty-eight women agreed participate in interviews filmed...
Hepatitis C virus (HCV) compromises Health-related Quality of Life (HRQL) with detriments to Physical, Mental and Social health domains. Treatment interferon ribavirin is associated side effects which further impair HRQL. New treatments appear potent, effective tolerable. However, Patient Reported Outcomes instruments that capture the impact on HRQL for people hepatitis are largely non-specific will be needed in new treatment era. Therefore, we developed a conceptually valid multidimensional...
We aimed to develop a new three-item assessment tool for daytime sleepiness in older adults, the Observation and interview-based Diurnal Sleepiness Inventory (ODSI) determine its validity, internal consistency, test-retest reliability, optimal cutoff score.A total of 133 elderly subjects including 73 patients with obstructive sleep apnea (OSA) (mean age, 79 y) 60 controls 80 were consecutively enrolled answered all questionnaires. The ODSI questionnaire was validated using Epworth Scale...
In their natural environment, fungi are subjected to a wide variety of environmental stresses which they must cope with by constantly adapting the architecture growing network. this work, our objective was finely characterize thallus development filamentous fungus Podospora anserina different constraints that simple implement in vitro and can be considered as relevant stresses, such nutrient-poor environment or non-optimal temperatures. At Petri dish scale, observations showed fungal is...
The filamentous fungus Podospora anserina is a good model to study the breakdown of lignocellulose, owing its ease culture and genetical analysis. Here, we show that able use wide range lignocellulosic materials as food sources. Using color assays, spectroscopy pyrolysis–gas chromatography mass spectrometry, confirm this ascomycete degrade lignin, primarily by hydrolyzing β–O-4 linkages, which facilitates nutrient uptake. We limited weight loss promoted when attacking Miscanthus giganteus...
Malgré l’intérêt suscité par le blues du post-partum dans la littérature scientifique, celui-ci reste un phénomène encore mal délimité sur plan clinique et nosographique. Notre objectif était d’en préciser les contours cliniques en comparant des femmes traversant ce à sans blues, de différences éventuelles styles interactifs mère-bébé leurs conséquences développement premier l’enfant. Le suivi longitudinal naissance aux deux mois vie l’enfant a concerné 22 dyades mère-bébé. Nos résultats...
To identify a simplified factor structure for the PROQOL-human immunodeficiency virus (HIV) questionnaire to improve measurement of health-related quality life (HRQL) HIV-positive patients in clinical care and research settings.HRQL data were collected using eight-dimension PROQOL-HIV from 2,537 (VESPA2 study). Exploratory analysis (EFA) confirmatory (CFA) validated simpler four-factor assessed invariance (MI). Multigroup effect sex, age, antiretroviral therapy (ART) on resulting scores....
In total, 679 HIV-positive patients from 4 clinics in Urumqi city were given structured questionnaires by the doctors or nurses treating them. Health-related quality of life (HRQL) was assessed using Chinese Patient-Reported Outcome Quality Life-HIV questionnaire versions Mandarin and Uyghur. This tool has been used other parts China several countries. Compared to France, Australia, United States, Brazil, Thailand, Cambodia, Senegal, Central-Southern (CS China), HRQL significantly lower...
Most studies on anesthesia focus the nervous system of mammals due to their interest in medicine. The fact that any life form can be anaesthetised is often overlooked although targets ion channel activities exist all living beings. This study examines impact lidocaine rice (
Based upon apical growth and hyphal branching, the two main processes that drive pattern of a fungal network, we propose here two-dimensions simulation based on binary-tree modelling allowing us to extract characteristics generic thallus growth. In particular, showed that, in homogeneous environment, can be optimized for exploration exploitation its surroundings with specific angular distribution branching. Two complementary methods extracting angle values have been used confront result...