Carolina Oi Lam Ung

ORCID: 0000-0003-1915-5099
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About
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Research Areas
  • Complementary and Alternative Medicine Studies
  • Health Systems, Economic Evaluations, Quality of Life
  • Pharmaceutical Practices and Patient Outcomes
  • Heart Failure Treatment and Management
  • Diabetes Treatment and Management
  • Pharmaceutical Economics and Policy
  • Liver Disease Diagnosis and Treatment
  • Healthcare Systems and Reforms
  • Pharmacological Effects of Natural Compounds
  • Pharmaceutical studies and practices
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • COVID-19 and Mental Health
  • Chronic Disease Management Strategies
  • Workplace Health and Well-being
  • Cardiovascular Function and Risk Factors
  • Employment and Welfare Studies
  • Antibiotic Use and Resistance
  • Phytochemistry Medicinal Plant Applications
  • Vaccine Coverage and Hesitancy
  • Metabolism, Diabetes, and Cancer
  • Traditional Chinese Medicine Analysis
  • Traditional Chinese Medicine Studies
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Pharmacology and Obesity Treatment
  • Hepatitis C virus research

University of Macau
2016-2025

The University of Sydney
2018-2024

Quality Research
2015-2024

Macau University of Science and Technology
2024

China Academy of Chinese Medical Sciences
2024

Peking University
2022

Kiang Wu Hospital
2019

City University of Macau
2018

University of Benin
2014-2016

Chinese University of Hong Kong
2003

Although past reports have identified a variety of prognostic factors in patients with severe chronic heart failure, previous studies not evaluated the interaction variables and drug treatment. We analyzed association 30 clinical, hemodynamic, biochemical survival 203 consecutive failure; all were assessed just before initiation treatment vasodilator drugs, subsequently followed for 6 to 94 months. By regression analysis, pretreatment serum sodium concentration was most powerful predictor...

10.1161/01.cir.73.2.257 article EN Circulation 1986-02-01

To evaluate possible mechanisms underlying the development of nitrate tolerance, we treated 35 patients who had severe chronic heart failure with a prolonged (48-hour) intravenous infusion nitroglycerin (6.4 micrograms per kilogram body weight minute) given either continuously or intermittently (12-hour infusions separated by intervals 12 hours). Intravenous produced immediate hemodynamic benefits in all patients, but magnitude this improvement was greatly diminished after 48 hours...

10.1056/nejm198709243171304 article EN New England Journal of Medicine 1987-09-24

To evaluate the concept that long duration of action is an advantageous property angiotensin-converting enzyme inhibitors in treatment severe heart failure, we randomly assigned 42 patients to therapy with either a short-acting inhibitor (captopril, 150 mg daily) or long-acting (enalapril, 40 for one three months while concomitant digoxin and diuretics was kept constant. The groups had similar hemodynamic clinical characteristics at base-line evaluation initial responses converting-enzyme...

10.1056/nejm198610023151402 article EN New England Journal of Medicine 1986-10-02

Renal function was evaluated in 104 patients with severe chronic heart failure whom we treated Captopril or enalapril. Seventy showed no change an improvement renal (group A)1 and 34 developed functional insufficiency B). Before converting-enzyme inhibition, group B received higher doses of furosemide (p< 0.02) had lower central venous pressures 0.05) than A patients. After 1 to 3 months excessive reduction left ventricular filling pressure (to less 15 mm Hg) mean arterial 60 noted 28 (82%)...

10.7326/0003-4819-106-3-346 article EN Annals of Internal Medicine 1987-03-01

Alzheimer's disease (AD) is a progressive brain disorder, and one of the most common causes dementia amnesia. Due to complex pathogenesis AD, underlying mechanisms remain unclear. Although scientists have made increasing efforts develop drugs for no effective therapeutic agents been found.Natural products their constituents shown promise treating neurodegenerative diseases, including AD. Thus, in-depth study medical plants, main active ingredients thereof against necessary devise agents.In...

10.1016/j.jare.2021.09.002 article EN cc-by-nc-nd Journal of Advanced Research 2021-09-08

Internet hospitals have been encouraged by the Chinese government to develop an innovative medical service model that mainly uses new internet-based technologies increase access health care and improve quality efficiency of delivery. However, academic exploration institutional sectoral development internet in China is scarce existing literature.This study aimed investigate policy interventions, trends, innovations China. It expected findings from this will contribute further innovation...

10.2196/22330 article EN cc-by Journal of Medical Internet Research 2021-05-25

Background The prevalence of transfusion-transmissible infections (TTIs) in blood donations is important for evaluating safety and potential risks to the population. This study investigated TTIs among donors Western China suggested measures policy-makers. Methods screening results 66,311 between 2005 2010 from a central center were analyzed. hepatitis B virus (HBV), C (HCV), human immunodeficiency (HIV), syphilis expressed percentages entire group as well groups by demographic...

10.1371/journal.pone.0094528 article EN cc-by PLoS ONE 2014-04-08

Introduction Burnout in healthcare providers (HPs) might lead to negative consequences at personal, patient-care and system levels especially during the COVID-19 pandemic. This study aimed investigate prevalence of burnout contributing variables, explore how, from health workforce management perspective, HPs’ experiences related carrying out duties would be associated with their burnout. Methods A cross-sectional, open online survey, informed by physical psychological attributes reportedly...

10.1371/journal.pone.0283239 article EN cc-by PLoS ONE 2023-03-16

When renal perfusion pressure is reduced in experimentally induced low-output states, glomerular filtration rate preserved by angiotensin II-mediated efferent arteriolar vasoconstriction, but available evidence man suggests that II supports function only to the extent it preserves systemic blood pressure. We performed simultaneous assessments of cardiac and 56 patients with severe chronic heart failure before after 1 3 months converting-enzyme inhibition. Among 29 a pretreatment under 70 mm...

10.1161/01.cir.74.4.766 article EN Circulation 1986-10-01

Real world evidence (RWE) and real-world data (RWD) are drawing ever-increasing attention in the pharmaceutical industry drug regulatory authorities (DRAs) all over due to their paramount role supporting development decision making. However, there is little systematic documentary analysis about how RWE was integrated for use by DRAs evaluating new treatment approaches monitoring post-market safety. This study aimed analyze discuss integration of into decision-making process from perspective...

10.3389/fmed.2021.669509 article EN cc-by Frontiers in Medicine 2021-05-31
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