- Cardiac, Anesthesia and Surgical Outcomes
- Airway Management and Intubation Techniques
- COVID-19 and healthcare impacts
- Complementary and Alternative Medicine Studies
- Respiratory Support and Mechanisms
- Orthopedic Surgery and Rehabilitation
- Inflammatory mediators and NSAID effects
- Nausea and vomiting management
- Mechanical Circulatory Support Devices
- Pharmacogenetics and Drug Metabolism
- Soft Robotics and Applications
- Pharmacology and Obesity Treatment
- Trauma Management and Diagnosis
- Cancer Genomics and Diagnostics
- Appendicitis Diagnosis and Management
- Bipolar Disorder and Treatment
- Enhanced Recovery After Surgery
- Nerve Injury and Rehabilitation
- Poisoning and overdose treatments
- Pregnancy and Medication Impact
- Intraocular Surgery and Lenses
- Blood transfusion and management
- Surgical Simulation and Training
- Advanced Radiotherapy Techniques
- Anesthesia and Pain Management
Stony Brook University
2020-2025
Stony Brook University Hospital
2020-2025
Stony Brook School
2023
Stony Brook Medicine
2020-2021
University of Rochester Medical Center
2014
University of Michigan
2011-2012
Merck & Co., Inc., Rahway, NJ, USA (United States)
2006
KU Leuven
2000
Ziekenhuisnetwerk Antwerpen Stuivenberg
2000
Pharmaceutical Product Development (United States)
2000
Opioid-based anesthesia and analgesia is a traditional component of perioperative care for the cardiac surgery patient. Growing enthusiasm Enhanced Recovery Programs (ERPs) coupled with evidence potential harm associated high-dose opioids suggests that we reconsider role in surgery.An interdisciplinary North American panel experts, using structured appraisal literature modified Delphi method, derived consensus recommendations optimal pain management opioid stewardship patients. Individual...
The popularization of large language chatbots such as ChatGPT has led to growing utility in various biomedical fields. It been shown that can provide reasonably accurate responses medical exam style questions. On the other hand, have known limitations which may hinder their education. We conducted a pragmatically designed study evaluate accuracy and completeness generated styles prompts, based on entry-level anesthesiology topics. Ninety-five unique prompts were constructed using topics from...
Objective The objective of this study was to examine the effect 3 doses rofecoxib (12.5, 25, and 50 mg) on pharmacodynamics pharmacokinetics warfarin. Methods Two single-dose (12.5 or mg with 25 30 oral warfarin, respectively, day 7 each period) trials (N = 12 men) 1 steady-state warfarin trial (25 rofecoxib; N 15, 13 men 2 women) were completed as two-period, randomized, balanced, crossover, double-blind designs. prothrombin time international normalized ratio (INR) S(–) R(+) enantiomers...
Purpose: In prostate brachytherapy, accurate positioning of the needle tip to place radioactive seeds at its target site is critical for successful radiation treatment. During procedure, deflection leads seed misplacement and suboptimal dose cancerous cells. practice, oncologists commonly use high‐speed hand insertion minimize displacement as well deflection. Effects speed during stiffness trocar (a solid rod inside hollow cannula) on are studied. Methods: Needle experiments into phantom...
Purpose: In prostate brachytherapy, a grid is used to guide needle tip toward preplanned location within the tissue. During insertion, deflects en route resulting in target misplacement. this paper, 18‐gauge insertion experiments into phantom were performed test effects of three parameters, which include clearance between hole and needle, thickness grid, speed. Measurement apparatus that consisted two datum surfaces digital depth gauge was developed quantify deflections. Methods: The...
Abstract Background The global coronavirus disease 2019 (COVID-19) pandemic offers the opportunity to assess how hospitals manage care of hospitalized patients with varying demographics and clinical presentations. goal this study was demonstrate impact densely populated residential areas on hospitalization identify predictors length stay mortality in COVID-19 one hardest hit counties internationally. Methods This a single-center cohort 1325 sequentially New York between March 2, 2020, May...
Abstract Background Chamomile administration may have desirable effects in the perioperative setting. Current practice, however, discourages chamomile use due to a theoretical increase bleeding. Therefore, we evaluated if acutely (within 4 h of ingestion) prolongs coagulation assays. Methods Eight healthy volunteers were randomized receive 2 interventions crossover design: (a) single dose extract capsule (500 mg) and (b) tea (3 g 150 mL water). Interventions separated at least 3 days apart...
Abstract Background Chamomile is consumed worldwide for enjoyment and its potentially desirable properties. Widespread patient resource websites, however, discourage preoperative chamomile intake, lest bleeding could worsen. This precaution, though, stems largely from indirect evidence in one case report. To evaluate if ingestion impacts coagulation assays via coumarin-like substances, we designed a randomized, placebo-controlled, crossover study. Materials methods Healthy volunteers were...
Introduction: Delayed sternal closure (open-chest) with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) may occur due to central cannulation, bleeding, or intolerance cardiac compression. An open-chest be a risk factor for VA-ECMO in-hospital mortality; we tested this hypothesis using our hospital’s ECMO registry. Methods: This is single-center study of patients treated between 2011-2021. Pediatric patients, hospital transfers, and perfusion failures were excluded. Univariate...
Introduction Patients with atrial fibrillation (AF) have multiple confounders that could affect the reliability of non-invasive blood pressure (NIBP). We sought to investigate if AF and paced rhythms (PR) modify NIBP accuracy against an invasive (IBP) reference, as compared sinus rhythm (SR), impact validity for procedural monitoring. Hypothesis Changes in heart between AF, SR PR, within a patient would not alter NIBP. Methods conducted observational study patients undergoing ablation...